A5029174144- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Viral Infections and Immunology Research
- Advanced MRI Techniques and Applications
- Acute Myocardial Infarction Research
- Cardiovascular Effects of Exercise
- Infective Endocarditis Diagnosis and Management
- Heart Failure Treatment and Management
- ECG Monitoring and Analysis
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Disease and Adiposity
- Cardiovascular Syncope and Autonomic Disorders
- Ion channel regulation and function
- Electrostatic Discharge in Electronics
- Hematopoietic Stem Cell Transplantation
- Heart Rate Variability and Autonomic Control
- Microbial Inactivation Methods
- Cardiac Arrest and Resuscitation
- Coronary Interventions and Diagnostics
Sheba Medical Center
2016-2025
Tel Aviv University
2015-2024
Johns Hopkins University
2012-2022
Technion – Israel Institute of Technology
2022
Maastricht University
2018-2021
Alzheimer's Association of Israel
2018
Johns Hopkins Medicine
2013-2015
Harvard University
2010-2012
Johns Hopkins Hospital
2012
Massachusetts General Hospital
2011
Although clopidogrel reduces the risk of cardiovascular episodes after coronary events and stenting, a substantial number incidents continue to occur.The antiplatelet effect was studied prospectively in 60 consecutive patients who underwent primary angioplasty (percutaneous intervention [PCI]) with stenting for acute ST-segment-elevation myocardial infarction (STEMI) determine whether variability response affects clinical outcomes. Patients were stratified into 4 quartiles according...
Abstract Aims To estimate the prevalence, incidence, mortality, and risk factors for atrial fibrillation (AF) in 195 countries territories from 1990 to 2017. Methods results Following methodologies used Global Burden of Disease Study 2017, mortality AF were analysed by age, sex, year, socio-demographic index (SDI), location. The percentage contributions major age-standardized deaths measured population attributable fractions. In there 37.57 million [95% uncertainty interval (UI) 32.55–42.59]...
Risk of Stroke/TIA in Patients With Atrial Fibrillation.Most strokes patients with atrial fibrillation (AF) arise from thrombus formation left appendage (LAA). Our aim was to identify LAA features associated a higher stroke risk AF using magnetic resonance imaging and angiography (MRI/MRA).The study included 144 nonvalvular who were not receiving warfarin underwent MRI/MRA prior catheter ablation for AF. volume, depth, short long axes neck, numbers lobes measured.Of the patients, 18 had or...
Successful catheter ablation of atrial fibrillation (AF) requires the creation transmural lesions in left atrium (LA). In addition, cardiac perforation is more likely to occur areas thin walls. The LA wall thickness thus relevant both for procedural efficacy and safety. This study sought evaluate regional patients with AF.The muscular (excluding fat) was measured by 64 slice computed tomography (CT) 60 persistent AF prior procedures. Measurements were performed all at 12 distinct locations,...
Abstract Background and Aims Arrhythmic mitral valve prolapse (AMVP) is linked to life-threatening ventricular arrhythmias (VAs), young women are considered at high risk. Cases of AMVP in with malignant VA during pregnancy have emerged, but the arrhythmic risk unknown. The authors aimed describe features high-risk who developed perinatal period assess if postpartum were associated a higher VA. Methods This retrospective international multi-centre case series included experienced least one...
The diagnosis of acute myocarditis is challenging. Nonspecific clinical presentation and an overlap with the myocardial infarction present a diagnostic dilemma. purpose this article to describe role cardiac MRI transthoracic echocardiography (TTE) in myocarditis.Thirty-two sequential patients (all male; average age, 33 years) clinically suspected were included. All underwent sequences dedicated for evaluation delayed enhancement TTE wall motion abnormalities (WMAs). Nine excluded because...
Purpose Detecting variations in myocardial water content with T 2 mapping is superior to conventional ‐weighted MRI since quantification enables direct observation of complicated pathology. Most commonly used techniques are limited achievable spatial and/or temporal resolution, both which reduce accuracy due partial‐volume averaging and misregistration between images. The goal this study was validate a novel free breathing sequence that overcomes these limitations. Methods proposed technique...
Transoesophageal echocardiography (TEE) and multidetector computed tomography (MDCT) currently serve as imaging modalities for left atrial appendage (LAA) occlusion preprocedural planning. We assessed the feasibility of MDCT-based models to predict correct size device LAA procedures.Patients planned underwent MDCT before implantation, which was used creating printing 3D models. Three cardiologists evaluated predicted by manual manipulation. These predictions were compared with actual...
Anti-Ro/La autoantibodies are especially prevalent in autoimmune diseases but also relatively frequent healthy adults. Their arrhythmogenic effect on the immature cardiac conductive system is well established, with substantial evidence demonstrating an increased risk for congenital atrioventricular block neonates of seropositive mothers. Despite their wide distribution and potential effect, there no large population studies conducted Thus, this first population-based study to examine...
BACKGROUND: Electroporation is a promising nonthermal ablation method for cardiac arrhythmia treatment. Although initial clinical studies found electroporation pulsed-field (PFA) both safe and efficacious, there are significant knowledge gaps concerning the mechanistic nature electrophysiological consequences of cardiomyocyte electroporation, contributed by paucity suitable human in vitro models. Here, we aimed to establish characterize functional model based on human-induced pluripotent...
Abstract Background Limited and inconsistent data exist regarding the impact of kidney function on outcomes following ablation procedures in patients with atrial fibrillation (AF). This study aimed to evaluate effectiveness safety AF a large national cohort stratified by levels estimated glomerular filtration rates (eGFR). Methods The Israeli Catheter Ablation Registry (ICAR) is prospective, multicenter who underwent pulmonary vein isolation (PVI) for treatment between 2019 2021. primary...
Obesity and overweight are strongly associated with cardiovascular morbidity mortality. However, there limited data on the association between excess weight risk of ectopic ventricular activity. We investigated body mass index (BMI) for activity (defined as multiple premature beats (≥3), bigeminy, nonsustained tachycardia or sustained tachycardia) during exercise stress testing among 22,516 apparently healthy men women who attended periodic health screening examinations years 2000 2014. All...
Background The past decade has brought major advances in therapy of patients presenting with acute coronary syndromes ( ACS ). Hypothesis outcomes atrial fibrillation (AF) improved over the years. Methods We evaluated time‐dependent changes clinical characteristics, management strategies, and associated AF observed during hospitalization enrolled biannual Israeli Surveys ACSIS ) between 2000 2013. divided surveys into early (2000–2006) late (2008–2013) time periods. Results study population...
Background Atrial fibrillation (AF) is associated with diminished cardiac function, and exercise tolerance. Hypothesis We sought to investigate the role of rehabilitation program (CR) in patients AF. Methods The study included 2165 consecutive that participated our CR between years 2009 2015. All were evaluated by a standard stress test (EST) at baseline, upon completion least 3 months training. Participants dichotomized according baseline fitness degree functional improvement. combined...