- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Structural Anomalies and Repair
- Glycogen Storage Diseases and Myoclonus
- Cardiac, Anesthesia and Surgical Outcomes
- Lysosomal Storage Disorders Research
- Takotsubo Cardiomyopathy and Associated Phenomena
- Respiratory Support and Mechanisms
- Coronary Artery Anomalies
- Lipoproteins and Cardiovascular Health
- Radiation Dose and Imaging
- Maternal and Neonatal Healthcare
- Cardiovascular Syncope and Autonomic Disorders
- COVID-19 Impact on Reproduction
- COVID-19 Clinical Research Studies
- Cerebral Venous Sinus Thrombosis
- Drug Solubulity and Delivery Systems
- Health Systems, Economic Evaluations, Quality of Life
- Acute Kidney Injury Research
- Ultrasound in Clinical Applications
Algarve Biomedical Center
2020-2025
Amazon (United States)
2025
Universidade Federal do Pará
2025
Universidade Federal de São Paulo
2025
Immersion (United States)
2025
University of Algarve
2012
A análise de óbitos maternos do estado Pará é essencial para compreender os impactos da COVID-19 nessa população e propor intervenções adequadas. Este estudo teve como objetivo investigar aspectos epidemiológicos, considerando dados sociodemográficos, estimar Anos Potenciais Vida Perdidos (APVP) mulheres que evoluíram à óbito por no Pará. Realizou-se um transversal retrospectivo com base em 78 registrados pela Secretaria Saúde Estado (SESPA) entre 2020 2021. Os foram analisados estatística...
In May 2021, MPEG issued a call for proposals the specification of new coding format haptic data. Following this call, baseline reference design and associated software implementation were defined representation It resulted in standard that defines complete generic framework delivery signals, allowing development current future applications mobile, gaming, virtual reality domains. This paper introduces results first phase haptics standard. includes description codec architecture,...
Abstract Introduction Acute aortic syndromes (AAS) are often the first form of presentation aorta artery diseases, especially classic acute dissection (AAD), with a high mortality rate. Distance to surgical center and consequently treatment time delay may influence prognosis this syndrome. Objective Characterize population that suffered an AAS at hospital without on-site cardiac surgery established emergent pathway in AAS. Analyze global gender differences in-hospital (primary outcome)...
Abstract Introduction Electrical cardioversion (ECV) remains the most cost-effective and safest method for acute restoration of sinus rhythm (SR) in patients with atrial fibrillation (Afib). However, ECV is unsuccessful at least 25% cases, particularly those long-standing persistent (LSP-Afib). Recent data suggests that control should be goal these patients, antiarrhythmic pretreatment may improve success rate ECV. Objectives To characterize a modern cohort LSP-Afib undergoing identify...
Abstract Introduction Patients with acute coronary syndrome (ACS) and diabetes mellitus (DM) are at a significantly higher risk of adverse cardiovascular (CV) outcomes compared to those without DM. Previous studies have suggested that insulin therapy in Type 2 DM is associated poorer ACS patients. Objective To evaluate whether insulin-treated patients who experience worse CV the current era advanced therapies for glycemic control. Methods This observational, retrospective study included...
Abstract Introduction Acute coronary syndrome (ACS) continues to be a frequent and prevalent event worldwide. Although in recent years there has been tendency reduce mortality associated with this cause, ischemic heart disease the main cause of death within patients established cardiovascular diseases. Objective To determine predictors adverse outcomes who have history an ACS, order alert clinicians for need risk factor control enhance secondary prevention. Methods Observational...
Abstract Introduction Atrial fibrillation (AF) shares numerous risk factors with acute coronary syndrome (ACS), making it a common comorbidity in these patients. Studies have shown that patients AF often worse prognosis compared to those sinus rhythm. However, the long-term impact of on clinical outcomes ACS remains poorly defined. Objective To assess effect cardiovascular (CV) during follow-up who experienced an ACS, comparing and without AF. Methods This observational, retrospective study...
Abstract Introduction Secondary prevention after acute coronary syndrome (ACS) primarily focuses on aggressive LDL cholesterol reduction, with a target of <55 mg/dL and at least 50% reduction from baseline. While high-intensity statins are the cornerstone therapy, additional agents such as ezetimibe PCSK9 inhibitors (PCSK9i) may be required. In some countries, including Portugal, PCSK9i have been restricted to cases severe dyslipidemia (LDL >140 or >100 risk factors),...
Acute coronary syndrome (ACS) is less frequent in young adults, but it has become a significant health problem, associated with the increasing prevalence of modifiable risk factors.To characterize patients admitted premature ACS, comparing those nonpremature ACS.We performed retrospective study encompassing Portuguese Registry (ProACS), two groups: one composed men than 55 and women 65 years old; other ≥55 ≥65 old at ACS admission. The primary endpoint was composite in-hospital mortality,...
Concerns surrounding the consequences of ionizing radiation (IR) have increased in interventional cardiology (IC). Despite this, ever-growing complexity diseases as well procedures can lead to greater exposure radiation. The aim this survey, led by Portuguese Association Interventional Cardiology (APIC), was evaluate level awareness and current practices on IR protection among its members.
Introduction and Objectives: Coronary chronic total occlusions (CTOs) of the right coronary artery (RCA) are a relatively common finding in context angiography. However, benefit revascularization remains controversial. Methods: A single-center retrospective cohort analysis prospectively collected outcomes CTO patients undergoing percutaneous intervention (PCI) 2019 2020. Patients were divided into two groups according to vessel treated (left [LCA]-CTO or RCA-CTO). The primary outcome was...
Introdução e Objetivos: A preocupação com as consequências da radiação ionizante (IR) aumentou entre a cardiologia de intervenção (IC). Ainda assim, os dados reportados sobre níveis referência dose (DRLs) são escassos nos laboratórios hemodinâmica em Portugal. Este estudo foi concebido para aceder às doses durante coronária percutânea complexa (PCI) definir respetivos DRLs futuras alcançar (ADs). Métodos: Estudo retrospetivo (2019 2020) doentes submetidos PCI complexa. Definiu-se como...
Tuberculosis remains the leading cause of preventable deaths worldwide and unsuccessful therapy is mainly due to non-compliance with very prolonged treatments, often associated severe side-effects. Overcoming this problem demands introduction drug carriers releasing antimicrobial agents in a targeted sustained manner, allowing reduction frequency dosing numbers. Nano- microparticles have taken forefront approach, providing means for desired improvement therapeutic schedules. Natural polymers...
Fabry disease is a rare lysosomal storage disorder caused by mutations in the GLA gene, resulting reduced or absent α-Gal A activity. Migalastat an oral chaperone therapy for patients with amenable variants. We previously reported case of 60-year-old male patient classic phenotype disease, presenting two variants: p.R356Q and p.G360R. Herein, we report that, although these missense variants are individually classified as to migalastat validated vitro human embryonic kidney-293 cell-based...
Coronary chronic total occlusions (CTOs) are relatively common findings in patients with type 2 diabetes mellitus (T2DM). However, the indication for percutaneous coronary intervention (PCI) and its clinical benefit these remain controversial.
In ST-segment elevation myocardial infarction (STEMI) the benefit of dual antiplatelet therapy is unequivocal, but optimal time to administer loading dose (LD) a P2Y12 inhibitor subject debate and disagreement. The main aim this study was characterize current practice in Portugal assess prognostic impact LD administration strategy, before versus during or after primary percutaneous coronary intervention (PCI). This multicenter retrospective based on Portuguese National Registry Acute...
No enfarte agudo do miocárdio com supradesnivelamento segmento ST (EAMcST) é inequívoco o benefício uso de dupla antiagregação plaquetar. O tempo ideal para administrar a dose carga inibidor recetor P2Y12 (DC‐iP2Y12) pouco consensual e motivo debate. principal objetivo trabalho foi caracterizar prática usada em Portugal avaliar impacto prognóstico da estratégia administração DC-iP2Y12, se antes ou durante/após angioplastia primária (AP). Estudo multicêntrico, retrospetivo, baseado no Registo...
Abstract Background Atherosclerotic cardiovascular disease (ASCVD) is a global health challenge, prompting widespread use of conventional risk assessment tools (SCORE2 in Europe and the ASCVD Risk calculator United States) to guide preventive strategies. Emerging evidence indicates that NTproBNP may help refine stratification. We investigate whether measuring primary prevention correlates with mortality enhances prediction compared score Methods Utilizing National Health Nutrition...
Abstract Background Atherosclerotic cardiovascular disease (ASCVD) is a global health challenge, prompting widespread use of conventional risk assessment tools (SCORE2 in Europe and the ASCVD Risk calculator United States) to guide preventive strategies. Emerging evidence indicates that high-sensitivity cardiac troponin (hsTn) may refine stratification. Objective We investigate whether measuring hsTnT primary prevention correlates with mortality enhances prediction compared score Methods...
A infecção por COVID-19 em gestantes tornou-se um problema de saúde pública, uma vez que contribuiu ao aumento da mortalidade materna no mundo e áreas Amazônia. Através geotecnologia foi analisada a distribuição dos óbitos maternos Estado do Pará, através estudo descritivo tipo ecológico, retrospectivo com uso dados secundários oficiais notificados entre 2020 2021 obtidos banco Secretaria Saúde Estado. Ocorreram na maioria 144 municípios compõem área sob estudo. Em cinco destes...
Abstract Introduction Acute kidney injury (AKI) due to contrast induced nephropathy (CIN) is a common complication after percutaneous coronary intervention (PCI) in patients with acute syndrome (ACS), and associated prolonged hospitalizations elevated cardio renovascular morbidity. Scientific evidence demonstrates that the mean volume of (VolC) ratio creatinine clearance (CrCl) (VolC/CrCl) are independent predictors CIN, but accepted optimal value remains controversial. Objective Population...
Abstract Introduction The use of aspirin in primary prevention (PP) remains a matter international debate. In type 2 diabetes mellitus (DM2) patients with high/very high cardiovascular (CV) risk, low dose may be considered for PP (class IIb, evidence level A) european guidelines the absence hemorrhagic contraindication. Objectives Our aim was to analyze in-hospital and one year follow-up (FU) outcomes acute coronary syndrome (ACS) DM2 without previous atherosclerotic CV disease (ASCVD)...