Hugo Costa

ORCID: 0000-0002-0670-6560
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About
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Research Areas
  • Acute Myocardial Infarction Research
  • Cardiac Imaging and Diagnostics
  • Coronary Interventions and Diagnostics
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Arrhythmias and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac Structural Anomalies and Repair
  • Glycogen Storage Diseases and Myoclonus
  • Cardiac, Anesthesia and Surgical Outcomes
  • Lysosomal Storage Disorders Research
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Respiratory Support and Mechanisms
  • Coronary Artery Anomalies
  • Lipoproteins and Cardiovascular Health
  • Radiation Dose and Imaging
  • Maternal and Neonatal Healthcare
  • Cardiovascular Syncope and Autonomic Disorders
  • COVID-19 Impact on Reproduction
  • COVID-19 Clinical Research Studies
  • Cerebral Venous Sinus Thrombosis
  • Drug Solubulity and Delivery Systems
  • Health Systems, Economic Evaluations, Quality of Life
  • Acute Kidney Injury Research
  • Ultrasound in Clinical Applications

Algarve Biomedical Center
2020-2025

Amazon (United States)
2025

Universidade Federal do Pará
2025

Universidade Federal de São Paulo
2025

Immersion (United States)
2025

University of Algarve
2012

Ángela López‐Sainz Fernándo Domínguez Luís R. Lopes Juan Pablo Ochoa Roberto Barriales‐Villa and 95 more Vicente Climent Marijke Linschoten Coloma Tirón Chiara Chiriatti Nuno Marques Torsten B. Rasmussen María Ángeles Espinosa Roy Beinart Giovanni Quarta Sergi César Ella Field José Manuel García‐Pinilla Zofia T. Bilińska Alison Muir Angharad M. Roberts Enrique Santas Esther Zorio María Luisa Peña‐Peña Marina Navarro Peñalver Adrián Fernández Julián Palomino-Doza Olga Azevedo Massimiliano Lorenzini Ana García‐Álvarez Dina Bento Morten K. Jensen Irene Méndez Laura Pezzoli Geòrgia Sarquella-Brugada Óscar Campuzano Esther González-López Jens Mogensen Juan Pablo Kaski Michael Arad Ramón Brugada Folkert W. Asselbergs Lorenzo Monserrat Iacopo Olivotto Perry Elliott Pablo García‐Pavía Torsten B. Rasmussen Morten K. Jensen Roberto Barriales‐Villa José M. Larrañaga‐Moreira Diego Alonso-García Ivonne J. Cárdenas-Reyes Marcos Cicerchia German García-Ferro Soledad García-Hernández Lorenzo Monserrat María Nöel-Bröger Juan Pablo Ochoa Martín Ortiz Olga Azevedo Dina Bento João Bispo Teresa Mota R Fernandes Hugo Costa Nuno Marques Vicente Climent Ana García‐Álvarez Sergi César Geòrgia Sarquella-Brugada Alison Muir Laura Pezzoli Giovanni Quarta Adrián Fernández Ella Field Juan Pablo Kaski Olga Azevedo Enrique Santas Chiara Chiriatti Iacopo Olivotto Ramón Brugada Óscar Campuzano Coloma Tirón Olga Azevedo Julián Palomino Doza Rafael Salguero‐Bodes María Valverde-Gómez María Ángeles Espinosa Irene Méndez Marta Cobo Marcos Fernándo Domínguez Luis Escobar Pablo García‐Pavía Esther González-López Ángela López‐Sainz Javier Segovia Silvia Vilches José Manuel García‐Pinilla Ainhoa Robles Mezcua Miguel A. López-Garrido Luis Morcillo‐Hidalgo

10.1016/j.jacc.2020.05.029 article EN publisher-specific-oa Journal of the American College of Cardiology 2020-07-01

A análise de óbitos maternos do estado Pará é essencial para compreender os impactos da COVID-19 nessa população e propor intervenções adequadas. Este estudo teve como objetivo investigar aspectos epidemiológicos, considerando dados sociodemográficos, estimar Anos Potenciais Vida Perdidos (APVP) mulheres que evoluíram à óbito por no Pará. Realizou-se um transversal retrospectivo com base em 78 registrados pela Secretaria Saúde Estado (SESPA) entre 2020 2021. Os foram analisados estatística...

10.55905/revconv.18n.1-223 article PT cc-by-nc Contribuciones a las Ciencias Sociales 2025-01-16

In May 2021, MPEG issued a call for proposals the specification of new coding format haptic data. Following this call, baseline reference design and associated software implementation were defined representation It resulted in standard that defines complete generic framework delivery signals, allowing development current future applications mobile, gaming, virtual reality domains. This paper introduces results first phase haptics standard. includes description codec architecture,...

10.1109/toh.2025.3539026 article EN IEEE Transactions on Haptics 2025-01-01

Abstract Introduction Acute aortic syndromes (AAS) are often the first form of presentation aorta artery diseases, especially classic acute dissection (AAD), with a high mortality rate. Distance to surgical center and consequently treatment time delay may influence prognosis this syndrome. Objective Characterize population that suffered an AAS at hospital without on-site cardiac surgery established emergent pathway in AAS. Analyze global gender differences in-hospital (primary outcome)...

10.1093/ehjacc/zuaf044.211 article EN European Heart Journal Acute Cardiovascular Care 2025-04-01

Abstract Introduction Electrical cardioversion (ECV) remains the most cost-effective and safest method for acute restoration of sinus rhythm (SR) in patients with atrial fibrillation (Afib). However, ECV is unsuccessful at least 25% cases, particularly those long-standing persistent (LSP-Afib). Recent data suggests that control should be goal these patients, antiarrhythmic pretreatment may improve success rate ECV. Objectives To characterize a modern cohort LSP-Afib undergoing identify...

10.1093/ehjacc/zuaf044.008 article EN European Heart Journal Acute Cardiovascular Care 2025-04-01

Abstract Introduction Patients with acute coronary syndrome (ACS) and diabetes mellitus (DM) are at a significantly higher risk of adverse cardiovascular (CV) outcomes compared to those without DM. Previous studies have suggested that insulin therapy in Type 2 DM is associated poorer ACS patients. Objective To evaluate whether insulin-treated patients who experience worse CV the current era advanced therapies for glycemic control. Methods This observational, retrospective study included...

10.1093/ehjacc/zuaf044.059 article EN European Heart Journal Acute Cardiovascular Care 2025-04-01

Abstract Introduction Acute coronary syndrome (ACS) continues to be a frequent and prevalent event worldwide. Although in recent years there has been tendency reduce mortality associated with this cause, ischemic heart disease the main cause of death within patients established cardiovascular diseases. Objective To determine predictors adverse outcomes who have history an ACS, order alert clinicians for need risk factor control enhance secondary prevention. Methods Observational...

10.1093/ehjacc/zuaf044.068 article EN European Heart Journal Acute Cardiovascular Care 2025-04-01

Abstract Introduction Atrial fibrillation (AF) shares numerous risk factors with acute coronary syndrome (ACS), making it a common comorbidity in these patients. Studies have shown that patients AF often worse prognosis compared to those sinus rhythm. However, the long-term impact of on clinical outcomes ACS remains poorly defined. Objective To assess effect cardiovascular (CV) during follow-up who experienced an ACS, comparing and without AF. Methods This observational, retrospective study...

10.1093/ehjacc/zuaf044.069 article EN European Heart Journal Acute Cardiovascular Care 2025-04-01

Abstract Introduction Secondary prevention after acute coronary syndrome (ACS) primarily focuses on aggressive LDL cholesterol reduction, with a target of <55 mg/dL and at least 50% reduction from baseline. While high-intensity statins are the cornerstone therapy, additional agents such as ezetimibe PCSK9 inhibitors (PCSK9i) may be required. In some countries, including Portugal, PCSK9i have been restricted to cases severe dyslipidemia (LDL >140 or >100 risk factors),...

10.1093/ehjacc/zuaf044.220 article EN European Heart Journal Acute Cardiovascular Care 2025-04-01

Acute coronary syndrome (ACS) is less frequent in young adults, but it has become a significant health problem, associated with the increasing prevalence of modifiable risk factors.To characterize patients admitted premature ACS, comparing those nonpremature ACS.We performed retrospective study encompassing Portuguese Registry (ProACS), two groups: one composed men than 55 and women 65 years old; other ≥55 ≥65 old at ACS admission. The primary endpoint was composite in-hospital mortality,...

10.1097/mca.0000000000001141 article EN Coronary Artery Disease 2022-02-21

Concerns surrounding the consequences of ionizing radiation (IR) have increased in interventional cardiology (IC). Despite this, ever-growing complexity diseases as well procedures can lead to greater exposure radiation. The aim this survey, led by Portuguese Association Interventional Cardiology (APIC), was evaluate level awareness and current practices on IR protection among its members.

10.1016/j.repc.2023.07.008 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2023-11-10

Introduction and Objectives: Coronary chronic total occlusions (CTOs) of the right coronary artery (RCA) are a relatively common finding in context angiography. However, benefit revascularization remains controversial. Methods: A single-center retrospective cohort analysis prospectively collected outcomes CTO patients undergoing percutaneous intervention (PCI) 2019 2020. Patients were divided into two groups according to vessel treated (left [LCA]-CTO or RCA-CTO). The primary outcome was...

10.1016/j.repc.2023.07.011 article PT cc-by-nc-nd Revista Portuguesa de Cardiologia 2024-01-19

Introdução e Objetivos: A preocupação com as consequências da radiação ionizante (IR) aumentou entre a cardiologia de intervenção (IC). Ainda assim, os dados reportados sobre níveis referência dose (DRLs) são escassos nos laboratórios hemodinâmica em Portugal. Este estudo foi concebido para aceder às doses durante coronária percutânea complexa (PCI) definir respetivos DRLs futuras alcançar (ADs). Métodos: Estudo retrospetivo (2019 2020) doentes submetidos PCI complexa. Definiu-se como...

10.1016/j.repc.2023.10.010 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2024-02-08

Tuberculosis remains the leading cause of preventable deaths worldwide and unsuccessful therapy is mainly due to non-compliance with very prolonged treatments, often associated severe side-effects. Overcoming this problem demands introduction drug carriers releasing antimicrobial agents in a targeted sustained manner, allowing reduction frequency dosing numbers. Nano- microparticles have taken forefront approach, providing means for desired improvement therapeutic schedules. Natural polymers...

10.3109/02652048.2012.726283 article EN Journal of Microencapsulation 2012-09-19

Fabry disease is a rare lysosomal storage disorder caused by mutations in the GLA gene, resulting reduced or absent α-Gal A activity. Migalastat an oral chaperone therapy for patients with amenable variants. We previously reported case of 60-year-old male patient classic phenotype disease, presenting two variants: p.R356Q and p.G360R. Herein, we report that, although these missense variants are individually classified as to migalastat validated vitro human embryonic kidney-293 cell-based...

10.2217/fca-2022-0080 article EN Future Cardiology 2023-01-01

Coronary chronic total occlusions (CTOs) are relatively common findings in patients with type 2 diabetes mellitus (T2DM). However, the indication for percutaneous coronary intervention (PCI) and its clinical benefit these remain controversial.

10.1016/j.repc.2023.07.009 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2023-12-21

In ST-segment elevation myocardial infarction (STEMI) the benefit of dual antiplatelet therapy is unequivocal, but optimal time to administer loading dose (LD) a P2Y12 inhibitor subject debate and disagreement. The main aim this study was characterize current practice in Portugal assess prognostic impact LD administration strategy, before versus during or after primary percutaneous coronary intervention (PCI). This multicenter retrospective based on Portuguese National Registry Acute...

10.1016/j.repce.2020.09.001 article PT cc-by-nc-nd Revista Portuguesa de Cardiologia (English Edition) 2020-10-01

No enfarte agudo do miocárdio com supradesnivelamento segmento ST (EAMcST) é inequívoco o benefício uso de dupla antiagregação plaquetar. O tempo ideal para administrar a dose carga inibidor recetor P2Y12 (DC‐iP2Y12) pouco consensual e motivo debate. principal objetivo trabalho foi caracterizar prática usada em Portugal avaliar impacto prognóstico da estratégia administração DC-iP2Y12, se antes ou durante/após angioplastia primária (AP). Estudo multicêntrico, retrospetivo, baseado no Registo...

10.1016/j.repc.2020.09.001 article PT cc-by-nc-nd Revista Portuguesa de Cardiologia 2020-10-01

Abstract Background Atherosclerotic cardiovascular disease (ASCVD) is a global health challenge, prompting widespread use of conventional risk assessment tools (SCORE2 in Europe and the ASCVD Risk calculator United States) to guide preventive strategies. Emerging evidence indicates that NTproBNP may help refine stratification. We investigate whether measuring primary prevention correlates with mortality enhances prediction compared score Methods Utilizing National Health Nutrition...

10.1093/eurheartj/ehae666.2705 article EN European Heart Journal 2024-10-01

Abstract Background Atherosclerotic cardiovascular disease (ASCVD) is a global health challenge, prompting widespread use of conventional risk assessment tools (SCORE2 in Europe and the ASCVD Risk calculator United States) to guide preventive strategies. Emerging evidence indicates that high-sensitivity cardiac troponin (hsTn) may refine stratification. Objective We investigate whether measuring hsTnT primary prevention correlates with mortality enhances prediction compared score Methods...

10.1093/eurheartj/ehae666.2731 article EN European Heart Journal 2024-10-01

A infecção por COVID-19 em gestantes tornou-se um problema de saúde pública, uma vez que contribuiu ao aumento da mortalidade materna no mundo e áreas Amazônia. Através geotecnologia foi analisada a distribuição dos óbitos maternos Estado do Pará, através estudo descritivo tipo ecológico, retrospectivo com uso dados secundários oficiais notificados entre 2020 2021 obtidos banco Secretaria Saúde Estado. Ocorreram na maioria 144 municípios compõem área sob estudo. Em cinco destes...

10.55905/oelv22n12-215 article PT cc-by-nc OBSERVATÓRIO DE LA ECONOMÍA LATINOAMERICANA 2024-12-27

Abstract Introduction Acute kidney injury (AKI) due to contrast induced nephropathy (CIN) is a common complication after percutaneous coronary intervention (PCI) in patients with acute syndrome (ACS), and associated prolonged hospitalizations elevated cardio renovascular morbidity. Scientific evidence demonstrates that the mean volume of (VolC) ratio creatinine clearance (CrCl) (VolC/CrCl) are independent predictors CIN, but accepted optimal value remains controversial. Objective Population...

10.1093/eurheartj/ehac544.1403 article EN European Heart Journal 2022-10-01

Abstract Introduction The use of aspirin in primary prevention (PP) remains a matter international debate. In type 2 diabetes mellitus (DM2) patients with high/very high cardiovascular (CV) risk, low dose may be considered for PP (class IIb, evidence level A) european guidelines the absence hemorrhagic contraindication. Objectives Our aim was to analyze in-hospital and one year follow-up (FU) outcomes acute coronary syndrome (ACS) DM2 without previous atherosclerotic CV disease (ASCVD)...

10.1093/eurheartj/ehad655.2564 article EN European Heart Journal 2023-11-01
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