A5068467736- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Aortic Disease and Treatment Approaches
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiovascular Disease and Adiposity
- Pulmonary Hypertension Research and Treatments
- Advanced X-ray and CT Imaging
- Cardiovascular Effects of Exercise
- Congenital Heart Disease Studies
- Aortic Thrombus and Embolism
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac pacing and defibrillation studies
- Aortic aneurysm repair treatments
- Cardiovascular Issues in Pregnancy
- Pericarditis and Cardiac Tamponade
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Chemotherapy-induced cardiotoxicity and mitigation
- Advanced MRI Techniques and Applications
- Cardiac electrophysiology and arrhythmias
Amsterdam University of Applied Sciences
2025
Amsterdam University Medical Centers
2025
Leiden University Medical Center
2014-2024
University Medical Center Utrecht
2022-2024
Utrecht University
2022-2024
Leiden University
2014-2023
Turku PET Centre
2017
Liverpool Hospital
2017
Netherlands Heart Institute
2017
UNSW Sydney
2017
Little is known about the association between bicuspid aortic valve (BAV) morphologic findings and degree of valvular dysfunction, presence aortopathy, complications, including surgery, dissection, all-cause mortality.To investigate BAV (raphe vs nonraphe) prognosis (including need for mortality).In this large international multicenter registry patients with treated at tertiary referral centers, 2118 were evaluated. Patients referred echocardiography from June 1, 1991, through November 31,...
The presence of hypo-attenuated leaflet thickening (HALT) and/or reduced motion on multi-detector row computed tomography (MDCT) has been proposed as a possible marker for early transcatheter aortic valve thrombosis. However, its association with abnormal haemodynamics echocardiography (another potential thrombosis) and clinical outcomes (stroke) remains unclear. present study evaluated the prevalence HALT MDCT echocardiography. In addition, occurrence ischemic stroke transient attack (TIA)...
Atrial fibrillation (AF) is an independent risk factor for ischaemic stroke. The CHA2DS2-VASc the most widely used stratification model; however, echocardiographic refinement may be useful, particularly in low AF patients. present study examined association between advanced parameters and stroke, of score.One thousand, three hundred sixty-one patients (mean age 65±12 years, 74% males) with first diagnosis baseline transthoracic echocardiogram were followed by chart review occurrence stroke...
Low gradient severe aortic stenosis (AS) with preserved left ventricular ejection fraction (LVEF) may be attributed to valve area index (AVAi) underestimation due the assumption of a circular shape outflow tract (LVOT) 2-dimensional echocardiography. The current study evaluated whether fusing Doppler and multidetector computed tomography (MDCT) data calculate AVAi results in significant reclassification inconsistently graded AS. In total, 191 patients < 0.6 cm2/m2 LVEF ≥ 50% (mean age 80 ± 7...
Percutaneous transcatheter tricuspid valve therapy is an evolving treatment option for patients with significant regurgitation (TR) deemed too fragile open heart surgery. The present study proposes comprehensive anatomical evaluation of the valve, right ventricle (RV), and vena cavae its spatial relationships coronary artery (RCA) using computed tomography (CT) investigates implications suitability current technologies. A total 250 (mean age 80 ± 7.2 years, 52.4% men) undergoing CT were...
Abstract Background and Aims Arrhythmic mitral valve prolapse (AMVP) is linked to life-threatening ventricular arrhythmias (VAs), young women are considered at high risk. Cases of AMVP in with malignant VA during pregnancy have emerged, but the arrhythmic risk unknown. The authors aimed describe features high-risk who developed perinatal period assess if postpartum were associated a higher VA. Methods This retrospective international multi-centre case series included experienced least one...
Multidetector row computed tomography (MDCT) may help to understand the underlying mechanisms of functional tricuspid regurgitation (TR), a highly prevalent valve disease with novel transcatheter therapies under development. The purpose present study was assess geometrical changes in patients TR using MDCT and correlate these grade assessed echocardiography. In 114 undergoing aortic implantation (47 men, age 81 ± 8 years), including 33 (28.9%) ≥ 3+, right ventricle (RV) were geometrically...
Transcatheter aortic valve replacement (TAVR) has been shown safe and feasible in patients with bicuspid (BAV) morphology. Evaluation of inter-ethnic differences morphology function root dimensions BAV is important for the worldwide spread this therapy subgroup patients. Comparisons between large European Asian cohorts have not performed, potential populations may implications TAVR.The present study evaluated two BAV.Aortic was defined on transthoracic echocardiography according to number...
Left atrial (LA) volume and LA epicardial fat are both substrates for fibrillation (AF), but may relate with AF at different (early vs. late) stages in the disease process. We evaluated associations between patients sinus rhythm (SR), paroxysmal (PAF), persistent/permanent AF.In total, 300 (100 SR, 100 PAF, AF) who underwent cardiac computed tomography angiography (CTA) were included. The mass posterior to quantified from CTA compared AF. Furthermore, four groups created by classifying into...
Epicardial adipose tissue located close to the atrial wall can change electric conduction of left atrium, potentially leading fibrillation (AF). The aim this study was assess whether an increased mass posterior atrium is related AF independent demographical and cardiovascular risk factors.Two hundred patients with 200 without who underwent computed tomographic angiography were included. quantified on images as Hounsfield Units between -195 -45. significantly larger in compared sinus rhythm:...
Quantitative mitral regurgitation (MR) grading remains challenging. This study evaluated the concept of integrating echocardiography and computed tomography for MR severity. Specifically, an integrated parameter was developed that combines true cross-sectional regurgitant orifice area (ROA) assessed with multi-detector row (MDCT) flow data from echocardiography.Systolic MDCT 73 patients, referred transcatheter aortic valve implantation (TAVI) who also had MR, were evaluated. The systolic...
The aim of this study was to compare the calcium burden aortic valve and coronary arteries with multidetector computed tomography (MDCT) in a propensity score-matched population patients bicuspid versus tricuspid valve. From an ongoing clinical registry who underwent MDCT, 70 210 were matched based on age, gender, cardiovascular risk factors, chest pain symptoms, MDCT indication. Aortic presence severity artery disease analyzed. Patients divided into age quintiles. median Agatston score (27...