A5088158435- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Cardiovascular Disease and Adiposity
- Radiation Dose and Imaging
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Ultrasound in Clinical Applications
- Medical Imaging Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Failure Treatment and Management
- Chemotherapy-induced cardiotoxicity and mitigation
- Healthcare cost, quality, practices
- Cardiac Valve Diseases and Treatments
- Coronary Artery Anomalies
- Lipoproteins and Cardiovascular Health
- Cardiac tumors and thrombi
- Peripheral Artery Disease Management
- Cardiovascular Effects of Exercise
- Emergency and Acute Care Studies
- Venous Thromboembolism Diagnosis and Management
- Aortic aneurysm repair treatments
Oregon Health & Science University
2016-2025
Greyston
2025
Massachusetts General Hospital
2015-2024
Japan Society
2019-2024
Charité - Universitätsmedizin Berlin
2024
Harvard University
2014-2023
University of Portland
2020-2023
Imaging Center
2022
RELX Group (United States)
2020
Cardiovascular Institute of the South
2020
Background— We investigated the ability of multidetector spiral computed tomography (MDCT) to detect atherosclerotic plaque in nonstenotic coronary arteries. Methods and Results— In 22 patients without significant stenoses, contrast-enhanced MDCT (0.75-mm collimation, 420-ms rotation) intravascular ultrasound (IVUS) one artery were performed. A total 83 segments imaged by IVUS (left main, 19; left anterior descending, 51; circumflex, 4; right coronary, 9). data sets evaluated for presence...
Coronary computed tomographic angiography (coronary CTA) can characterize coronary artery disease, including high-risk plaque. A noninvasive method of identifying plaque before major adverse cardiovascular events (MACE) could provide practice-changing optimizations in disease care.To determine whether detected by CTA was associated with incident MACE independently significant stenosis (SS) and risk factors.This prespecified nested observational cohort study part the Prospective Multicenter...
In this study, we investigated the diagnostic value and limitations of multidetector computed tomography (MDCT)-based noninvasive detection significant obstructive coronary artery disease (CAD) in a consecutive high-risk patient population with inclusion all segments.In prospective, blinded, standard cross-sectional technology assessment, cohort 33 patients positive stress test result underwent 16-slice MDCT selective angiography for CAD. We assessed accuracy segment-based patient-based...
Optimal management of patients with stable chest pain relies on the prognostic information provided by noninvasive cardiovascular testing, but there are limited data from randomized trials comparing anatomic functional testing.
Background— Noninvasive assessment of coronary atherosclerotic plaque and significant stenosis by multidetector computed tomography (MDCT) may improve early accurate triage patients presenting with acute chest pain to the emergency department. Methods Results— We conducted a blinded, prospective study in department between May July 2005 who were admitted hospital rule out syndrome (ACS) no ischemic ECG changes negative initial biomarkers. Contrast-enhanced 64-slice MDCT angiography was...
Background: Coronary artery calcium (CAC) is an established predictor of future major adverse atherosclerotic cardiovascular events in asymptomatic individuals. However, limited data exist as to how CAC compares with functional testing (FT) estimating prognosis symptomatic patients. Methods: In the PROMISE trial (Prospective Multicenter Imaging Study for Evaluation Chest Pain), patients stable chest pain (or dyspnea) and intermediate pretest probability obstructive coronary disease were...
Importance Trials showing equivalent or better outcomes with initial evaluation using coronary computed tomography angiography (cCTA) compared stress testing in patients stable chest pain have informed guidelines but raise questions about overtesting and excess catheterization. Objective To test a modified cCTA strategy designed to improve clinical efficiency vs usual (UT). Design, Setting, Participants This was pragmatic randomized trial enrolling participants from December 3, 2018, May 18,...
Cardiac magnetic resonance (CMR) imaging permits early triage of patients presenting to the emergency department with acute chest pain but has been limited by inability differentiate new from old myocardial infarction. Our objective was evaluate a CMR protocol that includes T2-weighted and assessment left ventricular wall thickness in detecting coronary syndrome department.In this prospective cohort observational study, we enrolled pain, negative cardiac biomarkers, no ECG changes indicative...
Purpose: To prospectively compare 64-section multidetector computed tomography (CT) and cardiac magnetic resonance (MR) imaging for the early assessment of myocardial enhancement infarct size after acute reperfused infarction (MI). Materials Methods: The study was HIPAA compliant approved by institutional review board. All participants gave written informed consent. Twenty-one patients (18 men; mean age, 60 years ± 13 [standard deviation]) were examined with CT MR 5 days or fewer a first MI....
To evaluate the accuracy of 64-section multidetector computed tomography (CT) for assessment perfusion defects (PDs), regional wall motion (RWM), and global left ventricular (LV) function.All myocardial infarction (MI) patients signed informed consent. The IRB approved study it was HIPAA-compliant. Cardiac CT performed in 102 (34 with recent acute MI 68 without). Multidetector images were analyzed PD, RWM abnormalities, LV function. Global function compared transthoracic echocardiography...
Arterial calcium (Ca) deposition has been identified as an active inflammatory process. We sought to test the hypothesis that local vascular inflammation predisposes subsequent arterial in humans.From a hospital database, we 137 patients (age, 61 ± 13 years; 48.1% men) who underwent serial positron-emission tomography/computed tomography (1-5 years apart). Focal was prospectively determined by measuring 18F-flourodeoxyglucose uptake (using baseline tomography) within predetermined locations...