A5054429253- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Cardiac Ischemia and Reperfusion
- Nitric Oxide and Endothelin Effects
- Lipoproteins and Cardiovascular Health
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune Response and Inflammation
- Cell Adhesion Molecules Research
- Atherosclerosis and Cardiovascular Diseases
- Diabetes Treatment and Management
- Inflammation biomarkers and pathways
- Estrogen and related hormone effects
- Bone health and osteoporosis research
- Wound Healing and Treatments
- Phytoestrogen effects and research
- Menopause: Health Impacts and Treatments
- Vitamin C and Antioxidants Research
- Chronic Lymphocytic Leukemia Research
- Cardiovascular Function and Risk Factors
- Cancer, Lipids, and Metabolism
- Microscopic Colitis
- Systemic Lupus Erythematosus Research
- Pancreatitis Pathology and Treatment
University of Messina
2016-2025
Weatherford College
2022
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2002-2020
Creative Commons
2015
American Association for the Study of Liver Diseases
2015
Christie's
2015
American Physical Therapy Association
2010
Kyungpook National University
2009
Sapienza University of Rome
2005
United States Nuclear Regulatory Commission
2004
Hepatitis B virus (HBV) infections in patients who lack detectable hepatitis surface antigen (HBsAg) are called occult infections. Although such have been identified with chronic C liver disease, their prevalence and clinical significance not known.
Background— We investigated whether electrical stimulation (STIM) of efferent vagus nerves may suppress nuclear factor (NF)-κB activation and the inflammatory cascade in hemorrhagic (Hem) shock. Methods Results— Rats were subjected to bilateral cervical vagotomy (VGX) or sham surgical procedures. Hem shock was induced by intermittent withdrawing blood until mean arterial pressure stabilized within range 35 40 mm Hg. Application constant voltage pulses caudal ends (STIM; 5 V, 2 ms, 1 Hz for...
Impaired wound healing is a well-documented phenomenon in experimental and clinical diabetes. Experimental evidence suggests that defect vascular endothelial growth factor (VEGF) regulation might be associated with wound-healing disorders. We studied the involvement of lipid peroxidation pathogenesis altered VEGF expression diabetes-related deficit by using an incisional skin-wound model produced on back female diabetic C57BL/KsJ db+/db+ mice their normal (db+/+m) littermates. Animals were...
Occult HBV infection is characterized by the persistence of DNA in liver individuals negative for surface antigen (HBsAg). may exist hepatocytes as a free genome, although factors responsible very low viral replication and gene expression usually observed this peculiar kind are mostly unknown. Aims study were to investigate whether genomic variability might account HBsAg negativity inhibition occult carriers, verify vitro capability strains. We studied isolates from 17 patients, 13 with 4...
To evaluate whether hepatitis B virus (HBV) preS/S gene variability has any impact on serum surface antigen (HBsAg) levels and to analyze the replication capacity of naturally occurring variants, sera from 40 untreated patients with HBV-related chronic liver disease (hepatitis e [HBeAg]-positive, n = 11; HBeAg-negative, 29) were virologically characterized. Additionally, phenotypic analysis three different variant isolates (carrying a 183-nucleotide deletion within preS1 region, preS2 start...
The endothelium is thought to play an important role in the genesis of atherosclerosis, and several lines evidence suggest that effect intervention on endothelial function might predict its involvement coronary disease progression rate cardiovascular events. Estrogen has direct effects blood vessel wall, indicating vascular may a key protective hormone replacement therapy (HRT). Raloxifene relaxes arteries vitro by estrogen receptor–dependent NO-dependent mechanism, thus suggesting this...
Abstract BACKGROUND Occult hepatitis B virus (HBV) infection frequently occurs in patients with HBV surface antigen (HBsAg)‐negative chronic liver disease, and much evidence suggests that it is a risk factor for hepatocellular carcinoma (HCC) development. However, to the authors' knowledge, no follow‐up study has been performed date evaluating HCC occurrence over time or without occult infection. METHODS A cohort of 380 HBsAg‐negative attending institution between 1991–2000 were evaluated...
In Brief Objective: We evaluated and compared the effects of phytoestrogen genistein, estrogen-progestogen therapy (EPT), placebo on hot flushes endometrial thickness in postmenopausal women. Design: Ninety healthy, women, 47 to 57 years age, were randomly assigned receive for 1 year continuous EPT (n = 30; mg 17β-estradiol combined with 0.5 norethisterone acetate), genistein 54 mg/day), or 30). Endometrial safety was by intravaginal ultrasounds at baseline, 6 12 months. Results: By...
Hepatitis B virus (HBV) and hepatitis delta (HDV) interplay was investigated by examining liver serum samples from 21 coinfected 22 HBV-monoinfected patients with chronic disease. Different real-time PCR assays were applied to evaluate intrahepatic amounts of HBV DNA, covalently closed circular DNA (cccDNA), pregenomic RNA (pgRNA), pre-S/S RNAs, HDV RNA. Besides levels, HBsAg concentrations in the sera also determined. HDV-coinfected cases showed significantly lower median levels (-5 log),...
A comprehensive investigation of psychological features in chronic patients is very important for tailoring effective treatments. In this study we tested anxiety, depression, health related quality life (HR-QoL), alexithymia, coping styles, and defense mechanisms, eighty-four with Crohn disease (CD) ulcerative colitis (UC). Participants reported low to moderate HRQoL apart from alexithymia. Women experienced lower QoL higher levels anxiety depressive symptoms. Coping strategies were distress...
The cholinergic anti-inflammatory pathway has not yet been studied in splanchnic artery occlusion (SAO) shock. We investigated whether electrical stimulation (STIM) of efferent vagus nerves suppresses the inflammatory cascade SAO Animals were subjected to clamping arteries for 45 min, followed by reperfusion. This surgical procedure resulted an irreversible state shock (SAO shock). Sham-operated animals used as controls. Two minutes before start reperfusion, rats bilateral cervical vagotomy...