A5079622958- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Ferroptosis and cancer prognosis
- Global Cancer Incidence and Screening
- Breast Implant and Reconstruction
- HER2/EGFR in Cancer Research
- BRCA gene mutations in cancer
- Reconstructive Surgery and Microvascular Techniques
- Inflammatory Biomarkers in Disease Prognosis
- Ovarian cancer diagnosis and treatment
- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Cancer Genomics and Diagnostics
- Sarcoma Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- AI in cancer detection
- Male Breast Health Studies
- Advanced Breast Cancer Therapies
- Cancer, Hypoxia, and Metabolism
- Bariatric Surgery and Outcomes
- PARP inhibition in cancer therapy
- Family Support in Illness
- Head and Neck Anomalies
- Nuclear Issues and Defense
Roswell Park Comprehensive Cancer Center
2020-2022
Saint Barnabas Medical Center
2011-2018
Blacktown & Mount Druitt Hospital
2018
Western Sydney University
2018
Memorial Sloan Kettering Cancer Center
2017
Kidwai Memorial Institute of Oncology
2007-2012
Triple negative breast cancer (TNBC) is the most aggressive subtype of with higher mortality than others. Pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) considered as a surrogate predict survival. Inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) regulator T cell activation, and reduction in ITPKC function known promote Kawasaki disease. Given role tumor infiltrating lymphocytes NAC since TNBC has abundant immune infiltration cancer, we hypothesized that expression...
Mild cold stress induced by housing mice with a 4T1 triple-negative breast cancer (TNBC) cell implantation model at 22 °C increases tumor growth rate pro-tumorigenic immune microenvironment (lower CD8 +T cells, higher myeloid-derived suppressor cells (MDSCs) and regulatory T-cells (Tregs)). Since also activates thermogenesis, we hypothesized that enhanced thermogenesis is associated more aggressive biology unfavorable (TME) in TNBC patients. A total of 6479 patients from METABRIC, TCGA,...
Breast cancer is the most commonly diagnosed and leading cause of cancer-related morbidity mortality in females worldwide. Significant disparities exist breast incidence mortalities between low- to middle- high-income countries. The purpose this study was analyze distribution prognostic predictive clinicopathological features invasive at a single institution Jamaica across three age groups.
Myeloid Sarcoma (MS), a rare extra hematopoietic carcinoma composed of blast cells, is located primarily in extramedullary sites such as skin, soft tissue, lymph nodes, and bone. MS usually presents the setting coexisting acute myeloid leukemia (AML) myeloproliferative disorders. Gastrointestinal involvement (GI) extremely from nonspecific abdominal symptoms to obstruction. Eight cases sarcoma involving duodenum including current case have been reported, overall mean age being 40 years...
Introduction: Multidisciplinary breast conference (BC) that discusses different clinicopathological aspects of disease creates a sound, complete and unique treatment plan for each patient. The aim this study was to investigate the role weekly tumor boards in patient management modifications. Methods: From June 2010 2011, 242 patients (Stage 0 Stage 4 cancer) were prospectively presented before multidisciplinary team. Presentation included clinical data, imaging pathological review followed...
Background: It is estimated that 2240 males in the United States will develop invasive breast cancer (BC) 2013, resulting 410 deaths. Overall, male cancers (MBCs) are diagnosed with larger tumor size, more frequent lymphatic invasion, and advanced stage compared to their female counterparts. Several risk factors have been elucidated for development of MBC, this paper aims critically review existing literature on at-risk populations provide screening recommendations. Methods: A comprehensive...
<b>Background:</b> Many patients with renal cell carcinoma (RCC) present disease involving the adjacent viscera. Although survival in such is poor, surgery remains only proven modality of treatment. We describe our experience radical nephrectomy for locally invasive RCC over a five-year period. <b> Study Design:</b> A retrospective analysis records all who had undergone between January 1999 and December 2004 at institute. Materials Methods:</b> During study period, 102 underwent institute,...