- Dental Implant Techniques and Outcomes
- Dementia and Cognitive Impairment Research
- Periodontal Regeneration and Treatments
- Dental Radiography and Imaging
- Sinusitis and nasal conditions
- Oral microbiology and periodontitis research
- Oral and gingival health research
- Head and Neck Surgical Oncology
- Folate and B Vitamins Research
- Oral and Maxillofacial Pathology
- Alzheimer's disease research and treatments
- Functional Brain Connectivity Studies
- Phytochemicals and Antioxidant Activities
- Health and Wellbeing Research
- Parkinson's Disease Mechanisms and Treatments
- Cleft Lip and Palate Research
- dental development and anomalies
- Bone Tissue Engineering Materials
- Endodontics and Root Canal Treatments
- Orthodontics and Dentofacial Orthopedics
- Natural Products and Biological Research
- Health and Well-being Studies
- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Autophagy in Disease and Therapy
Hanyang University
2016-2025
University of British Columbia
2024
British Columbia Children's Hospital
2024
Pukyong National University
2024
Anyang University
2023-2024
RBio (South Korea)
2021
Kyung Hee University
2004-2020
Seoul National University Hospital
1997-2020
Columbia University
2018
Silla University
2014-2016
In order to develop a new skin whitening agent, safflower (Carthamus tinctorius L.) seeds were evaluated for melanogenesis inhibitory activity and its active principles identified following activity-guided isolation. The 80% aqueous methanol extract ethyl acetate fraction from showed significant inhibition mushroom tyrosinase. Three compounds, N-feruloylserotonin, N-(p-coumaroyl)serotonin, acacetin, isolated the as principles. Compared with arbutin (IC50=0.223 mM), IC50 values of these...
We aimed to identify and characterize subtypes of Alzheimer’s disease (AD) exhibiting different patterns regional brain atrophy on MRI using age- gender-specific norms volumes. AD subjects included in the Alzheimer's Disease Neuroimaging Initiative study were classified into based standardized values (Z-scores) hippocampal cortical volumes with reference obtained from 222 cognitively normal (CN) subjects. Baseline longitudinal changes clinical characteristics over 2 years compared across...
An optically controlled energy-harvesting smart window that incorporates a semitransparent solar cell with photosensitive liquid crystal (LC) layer is demonstrated. The LC can switch between transparent (day mode) and an opaque (night state depending upon the incident radiation. Combined photovoltaic cell, this provides template for future systems.
Mer signaling participates in a novel inhibitory pathway TLR activation. The purpose of the present study was to examine role down-regulation TLR4 activation-driven immune responses mice, i.t.-treated with LPS, using specific Mer-blocking antibody. At 4 h and 24 after LPS treatment, expression protein alveolar macrophages lung tissue decreased, sMer BALF increased significantly, activation increased. Pretreatment anti-Mer antibody did not influence levels levels. Anti-Mer significantly...
We present a nonconventional membrane surface modification approach that utilizes topography to manipulate the tribology of foulant accumulation on water desalination membranes via imprinting submicron titanium dioxide (TiO2) pillar patterns onto molecularly structured, flat surface. This versatile overcomes constraint conventional relying interfacial polymerization inevitably leads formation ill-defined topography. Compared nonpatterned membranes, patterned showed significantly improved...
Purpose: With the increasing prevalence of orthodontic treatment in adults, clear aligner treatments are becoming more popular.The aim this study was to evaluate effect on periodontal tissue and compare with fixed appliances (FA) (CAT) periodontitis patients.Methods: A total 35 patients who underwent Department Periodontology were included study.After meticulous oral hygiene education, FA or CAT, analyzed patient outcomes depending strategy.Clinical parameters assessed at baseline after...
To evaluate the long-term influence of residual bone height (RBH), sinus membrane perforation and presence voids on survival implants placed simultaneously with lateral maxillary floor augmentation (MSFA).A total 207 patients (613 implants) who underwent MSFA from 1999 to 2003 followed up until 2018 were included in this study. RBH marginal loss assessed using a series panoramic periapical radiographs. Cumulative rates (CSR) log-rank tests hazard ratios implant failure according RBH,...
Abstract Background The aim of this comparative study was to evaluate the clinical outcome nonrepair perforated maxillary sinus membrane compared nonperforated cases. Materials and Methods A retrospective performed by identifying all lateral window augmentation procedures, which were done during a defined period. Demographic data, systemic diseases, smoking habits patients recorded. Thickness Schneiderian amount residual bone before surgery measured cone‐beam computed tomography (CBCT). In...
This study aimed to investigate the association between genetic burden of systemic lupus erythematosus (SLE) and loss tolerance self-nuclear antigens in preclinical stage. We analysed data from 349 Korean individuals who tested positive for autoantibodies stage, along with 33,596 healthy controls 2057 patients SLE. Genome-wide pathway-specific polygenic risk scores (PRSs) SLE were calculated based on 180 known non-human leukocyte antigen (non-HLA) loci, HLA-DRB1 classical alleles, predefined...
Enterococcus faecalis is one of the most common opportunistic pathogens responsible for nosocomial infections, and its LTA known as an important virulence factor causing inflammatory responses. As chemokines play a key role in diseases by triggering leukocyte infiltration into infection site, we purified EfLTA investigated effect on expression chemokines, IP-10, MIP-1α, MCP-1, murine macrophages. induced these at mRNA protein levels. TLR2, CD14, MyD88 were involved EfLTA-induced chemokine...
Abstract Objectives: This study was designed to evaluate the effect of bone graft materials and collagen membranes in ridge splitting procedures with immediate implant placement using a dog model. Materials methods: Mandibular premolars were extracted five beagle dogs. After 3 months, three OsseoSpeed ™ implants performed bilaterally. The gaps between allocated according following eight treatment modalities; Group 1(no graft), 2 (autogenous bone), (Bio‐Oss ® Collagen), 4 ), 5 (no...
Purpose:The aim of this study is to evaluate the buccal and lingual bone thickness in anterior teeth relationship between tissue biotype.Methods: Three male two female human cadaver heads (mean age, 55.4 years) were used study.First, biotype periodontium was evaluated categorized into a thick or thin group.Next, full reflections mandible maxilla expose underlying for accurate measurements regions performed.After removal half alveolar bone, probe with stopper measure plate at crest (AC), 3 mm...
Despite potential implications for the early detection of impending AD, very little is known about differences large scale brain networks between amnestic MCI (aMCI) with high cerebral amyloid beta protein (Aβ) deposition (i.e., aMCI+) and aMCI no or Aβ aMCI-). We first aimed to extend current literature on altering intrinsic functional connectivity (FC) default mode network (DMN) salience (SN) from CN AD dementia. Second, we further examined DMN SN aMCI-, aMCI+, CN. Forty-three older adult...
Rheumatoid arthritis (RA) and periodontitis are common chronic inflammatory diseases is known to be more severe in patients with RA. Based on a paucity of studies about the relationship between conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) periodontitis, this prospective study aimed evaluate adjunctive effect csDMARDs response nonsurgical periodontal treatment Thirty-two RA (RA group) 32 systemically healthy (control were included study. The group treated csDMARDs,...