A5038428719- Advanced Glycation End Products research
- S100 Proteins and Annexins
- Metabolism, Diabetes, and Cancer
- Epigenetics and DNA Methylation
- T-cell and B-cell Immunology
- Computational Drug Discovery Methods
- Phytochemistry and Bioactivity Studies
- Fungal Biology and Applications
- Cancer Treatment and Pharmacology
- Esophageal Cancer Research and Treatment
- Immune Cell Function and Interaction
- Cancer-related Molecular Pathways
- Advanced Breast Cancer Therapies
- Immune cells in cancer
- Immunotherapy and Immune Responses
Chulalongkorn University
2022-2023
Mahidol University
2014-2017
Siriraj Hospital
2014-2017
Cancer-associated fibroblasts and high mobility group box 1 (HMGB1) protein have been suggested to mediate cancer progression chemotherapy resistance. The role of such in HMGB1 production breast is unclear. This study aimed investigate the effects cancer-associated on expression cells its chemotherapeutic response. Breast (BCFs) non-tumor-associated (NTFs) were isolated from human cancers or adjacent normal tissues established as primary cultures vitro. After confirmation activated status...
High-mobility group box 1 (HMGB1) is increased in breast cancer cells as the result of exposure to secreted substances from cancer-associated fibroblasts and plays a crucial role progression drug resistance. Its effect, however, on expression programmed death ligand (PD-L1) has not been investigated. This study aimed investigate mechanism HMGB1 through receptors for advanced glycation end products (RAGE) cell migration/invasion PD-L1 cells.A 3-dimensional (3-D) migration invasion assay...
Pleurotus pulmonarius is an affordable edible fungus extensively utilized in food and traditional medicine. This study aims to comprehensively profile the water-soluble bioactive compounds P. identify those responsible for modulating monocyte immune response. The crude extract, prepared through hot water extraction, was analyzed its biological activities using untargeted LC/MS-MS analysis molecular docking. potential compound-targeted proteins monocytes were investigated further identified...
IntroductionThe influence of cancer-associated fibroblasts (CAFs) and high mobility group box 1 (HMGB1) has been recognized in several cancers, although their roles breast cancer are unclear. The present study aimed to determine the levels prognostic significance α-smooth muscle actin-positive (ASMA+) CAFs, plus HMGB1 receptor for advanced glycation end products (RAGE) cells.Materials MethodsA total 127 samples, including 96 malignant 31 benign, were examined ASMA, HMGB1, RAGE by...
Abstract STAT4 (Signal Transducer Activator of Transcription factor 4) polymorphisms are risk factors contributed to autoimmune disease. While has a dominant role in promoting interferon-gamma (IFN-g) production T and NK cells, its existence function exert human dendritic cells (DCs) still unknown. To characterize the expression peripheral DCs, we isolated DCs from buffy coat health blood donors (n = 4). The ex vivo were enriched sorted into 3 subtypes including plasmacytoid (pDCs, CD123 +),...