- Forensic Toxicology and Drug Analysis
- Respiratory Support and Mechanisms
- Anesthesia and Sedative Agents
- Atrial Fibrillation Management and Outcomes
- Respiratory and Cough-Related Research
- Pharmacological Receptor Mechanisms and Effects
- Intensive Care Unit Cognitive Disorders
- Cannabis and Cannabinoid Research
- Asthma and respiratory diseases
- Poisoning and overdose treatments
UMass Memorial Medical Center
2020-2023
UMass Memorial Health Care
2020-2022
Purpose Previous studies analyzing neuromuscular blocking agents (NMBAs) in acute respiratory distress syndrome (ARDS) have evaluated the benefit of cisatracurium with conflicting results, and data evaluating other NMBAs remains limited. The objective this study was to compare efficacy safety vecuronium ARDS. Materials methods A single-center, retrospective, propensity matched review patients who received or continuous infusions between October 1, 2017 June 30, 2020 for ARDS conducted....
<h3>Introduction</h3> We have developed a novel cough challenge methodology and previously showed that evoked maximal responses, defined as E<sub>max</sub>, better discriminate health from disease than traditional endpoints.<sup>1</sup> It is unclear how other factors influence E<sub>max</sub> or it relates to the low rates observed in health. therefore aimed investigate variability, repeatability influences on larger group of healthy volunteers. <h3>Objective</h3> To assess maximum...
Introduction: New onset atrial fibrillation is common in sepsis. Norepinephrine, the first-line vasopressor for septic shock, can cause tachyarrhythmias. Limited data suggests switching norepinephrine to phenylephrine may decrease heart rate and improve control. This study compared effect of this transition on clinical interventions control patients who developed norepinephrine. Methods: A single-center, retrospective cohort shock admitted medical surgical intensive care units at UMass...
Critical Care Medicine: January 2022 - Volume 50 Issue 1 p 461 doi: 10.1097/01.ccm.0000810036.31911.63