Stable gels can be obtained from water and organic solvents with bis(amino acid) oxalyl amides. In aqueous systems lipophilic interactions lateral hydrogen bonding dominate their self-organisation into gel fibres as depicted here. organic-solvent intermolecular governs the self-organisation. Gels were studied by 1H NMR, FTIR, TEM, SEM single crystal X-ray analysis. Bis(LeuOH) (1 a), bis(ValOH) (2 a) bis(PhgOH) (5 (Phg denotes (R)-phenylglycine) amides are efficient low molecular weight...

A non-covalent self-assembled chiral alanyl aminopyridine ligand exhibits supramolecular chirality in solution, independent of the organic solvent used. The assemblies is completely inverted by complexation to zinc ions. To date, such a metal-ligand system has not been reported literature.

Solvatomorphism has been found between two series of complexes the composition [M(bpy)3]2[NbO(C2O4)3]Cl·nH2O [M = Fe2+ (1, 2), Co2+ (3, 4), Ni2+ (5, 6), Cu2+ (7) and Zn2+ (8, 9); bpy 2,2′-bipyridine)], crystallizing in monoclinic space groupP21/c [3, 5, 8 (n 11)] or orthorhombic groupP212121 [2, 4, 6, 7 12)]. All structures contain symmetry independent [M(bpy)3]2+ cations, one [NbO(C2O4)3]3− anion, Cl− crystal water molecules. The cations possess a trigonally distorted octahedral geometry,...

Metal complexes of iminodiacetamide (imda) ligands and metal ions Zn(II), Cu(II), Ni(II), Co(II) were prepared using eight imda (L1–L8) substituted with groups different steric electronic properties on the central amine N atom (H atom, methyl, isopropyl, benzyl) para position phenyl rings (nitro dimethylamino). The effect these substituents stoichiometry (ML ML2), geometry, stereochemistry (mer, trans-fac, cis-fac) was studied in solid state, solution, by density functional theory...

A variety of structurally different complexes the isopropyl-bis(2-picolyl)amine (iPr-bpa) ligand were prepared with ZnA2 and CuA2 salts (A = Br–, Br–/PF6–, BF4–/F–, ClO4–). The choice counterion affected stoichiometry, coordination number, geometry, formation geometrical isomers. Crystal structures four Zn(II) complexes, namely, two monomers (mer-[Zn(iPr-bpa)Br2] fac-[Zn(iPr-bpa)Br2]), one F–-bridged dimer ([Zn2(μ-F)2(iPr-bpa)2](BF4)2), ML2 complex ([Zn(iPr-bpa)2](ClO4)2) determined, their...

Heterobimetallic Re( i ) ferrocene dipyridylamine complexes showed antiproliferative effects comparable to cisplatin on colon cancer cells, whereas the benzimidazo[1,2- a ]quinoline complex accumulated in lysosomes and interacted with biomolecules.

Chelating 1,4-disubstituted mono- (8a-8d) and bis-1,2,3-triazole-based (9a-11a) ligands were prepared by regioselective copper(i)-catalysed 1,3-dipolar cycloaddition of terminal alkynes with aromatic azides, together bioconjugate 13a synthesized amide coupling l-phenylalanine methyl ester to 11a. Cu(ii) Zn(ii) complexes single crystal structures determined for 8aCu, 8dCu, 9cCu 10cCu, as well the free 10a 10c. The in situ studied NMR spectroscopy, while stoichiometry solution was UV-Vis...

The influences of an oxygen ligand on the structural, magnetic and electronic properties octahedral niobium cluster-based oxides oxychlorides are reported. Nb6 metal cluster is edge-bridged by twelve inner ligands additionally bonded to six apical form Nb6Li12La6 units (L = Cl, O) wherein chlorine perfectly ordered. Oxygen favours interconnection clusters via double Oi–a/Oa–i bridges in a similar way Si–a/Sa–i found Chevrel phases based face capped Mo6Li8La6 units. Periodic density...

Triphenylphosphine–amino acid bioconjugates Ph 2 P‐ p C 6 H 4 ‐Aa‐OR [Lig; Aa = glycine ( 1G ), alanine 2A valine 3V isoleucine 4I proline 5P or phenylalanine 6F )] were synthesized and used as monodentate ligands for the preparation of twelve metal complexes, [MCl (Lig) ] (M Pd II Pt ). All prepared compounds characterized by spectroscopic methods, structures ligand complexes , determined X‐ray single‐crystal diffraction. The cis trans configurations square‐planar investigated solution NMR...

This paper describes the synthesis and characterization of 21 chiral monodentate ligands L , assembled three building blocks utilizing amide bonds: a metal binding triphenylphosphine, cyclic diamine an additional substituent for fine‐tuning steric and/or electronic properties. Cis square‐planar complexes Rh I Pt II with ML 2 stoichiometry have been prepared characterized by spectroscopic methods (NMR, IR, UV‐Vis, CD) DFT calculations. A key feature is prochiral coordination sphere “ backdoor...

Abstract Ferrocene derivatives with mono‐ ( 8a – c ) and bis‐1,2,3‐triazolyl 9 10a 13c chelating groups were synthesized by regioselective copper(I)‐catalysed 1,3‐dipolar cycloaddition of terminal alkynes ferrocene azides. Metal complexes the ligands prepared Cu(II) Zn(II) salts. Crystal structures 11a determined, as well [Cu( 2 ](CF 3 SO Cu 8c (CH OH) ](BF 4 ). In addition to NMR UV–Vis spectroscopy, metal characterized cyclic voltammetry. The cytotoxic effect conjugates their was explored,...

Modifications of the chiral side chains bpa and imda ligands lead to different metal ion coordination hydrogen bonding ability.

Oxazoline amino acid bioconjugates were synthesized; the relative stability of a supramolecular dimer tris-derivative was investigated using mean absolute error values (MAE), derived from 1 H NMR experiments and DFT calculations.

Among ruthenium complexes studied as anticancer metallodrugs, NKP-1339, NAMI-A, RM175, and RAPTA-C have already entered clinical trials due to their potent antitumor activity demonstrated in preclinical studies reduced toxicity comparison with platinum drugs. Considering the advantages of ruthenium-based drugs cytostatic organometallic triazole- coumarin-derived ligands, we set out synthesize Ru(II) coumarin-1,2,3,-triazole hybrids (L) general formula [Ru(L)(p-cymene)(Cl)]ClO

Abstract Magnetic interactions in solid‐state tantalum cluster compounds have been evidenced by using magnetic susceptibility measurements and corroborated broken‐symmetry DFT calculations. The three selected are based on [Ta 6 X 12 (H 2 O) ] 3+ (X=Cl or/and Br) units with edge‐bridged Ta octahedral clusters. Although two of them crystallise the tetragonal space group I 4 1 / a , all exhibit similar arrangement paramagnetic clusters related to diamond structural framework ( Fd m group)....

Heme and nonheme-type flavone synthase enzymes, FS I II are responsible for the synthesis of flavones, which play an important role in various biological processes, have a wide range biomedicinal properties including antitumor, antimalarial, antioxidant activities. To get more insight into mechanism this curious enzyme reaction, nonheme structural functional models were carried out by use mononuclear iron, [FeII(CDA-BPA*)]2+ (6) [CDA-BPA =...