A5038249799- Photoacoustic and Ultrasonic Imaging
- Nanoplatforms for cancer theranostics
- Ultrasound and Hyperthermia Applications
- Thermography and Photoacoustic Techniques
- Extracellular vesicles in disease
- Photodynamic Therapy Research Studies
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- MicroRNA in disease regulation
- Conducting polymers and applications
- Nanoparticle-Based Drug Delivery
- Immunotherapy and Immune Responses
- Supercapacitor Materials and Fabrication
- Luminescence and Fluorescent Materials
- Viral gastroenteritis research and epidemiology
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Ultrasound Imaging and Elastography
- Respiratory viral infections research
- Viral Infections and Immunology Research
- RNA modifications and cancer
- Immune cells in cancer
- MXene and MAX Phase Materials
- Pancreatic and Hepatic Oncology Research
- Optical Imaging and Spectroscopy Techniques
South China Normal University
2016-2025
Shanghai East Hospital
2020-2025
Wuhan University of Science and Technology
2017-2025
Qingdao University
2021-2024
Tongji University
2024
Wuhan University
2021-2024
Wuhan Children's Hospital
2023-2024
Heilongjiang University of Chinese Medicine
2024
South Central Minzu University
2022-2023
Changchun University of Science and Technology
2023
Gelatin biopolymer-supported deep eutectic solvent gels offer greatly enhanced mechanical properties and nonvolatility compared to their hydrogel analogues for devices that utilize ionically conducting soft materials.
Developing multifunctional phototheranostics with nanoplatforms offers promising potential for effective eradication of malignant solid tumors. In this study, we develop a phototheranostic by combining photothermal therapy (PTT) and photoacoustic (PAT) based on tumor-targeting nanoagent (DBCO-ZnPc-LP). The DBCO-ZnPc-LP was facilely prepared self-assembling single lipophilic near-infrared (NIR) dye zinc(II)-phthalocyanine (ZnPc) lipid-poly(ethylene glycol) (LP) following modified further...
The preparation of multifunctionalized luminophores with full-color emission based on an identical core skeleton is a significative but challenging research topic. In this work, eight donor-donor-acceptor (D-D-A)-type luminogens central carbazole bearing C6 hydrocarbon chain were designed by using different kinds donor and acceptor units the left right, synthesized in good yields. These D-D-A derivatives display deep-blue, sky-blue, cyan, green, yellow-green, yellow, orange red fluorescence...
Invited for the cover of this issue are Zhao Chen at Jiangxi Science and Technology Normal University Yue Sun Tiangong University. For picture, yellow ball containing character "D" represents donor, green "A" acceptor. The image depicts eight donor-donor-acceptor-type carbazole derivatives that display full-color emission, a luminogen shows red to near-infrared mechano-fluorochromism photodynamic therapy effect. Read full text article 10.1002/chem.202203797.
Hepatocellular carcinoma (HCC) is a serious global health concern, accounting for about 90% of all liver cancer instances. Surgical treatment fundamental aspect HCC management; however, the challenge postoperative recurrence significantly impacts mortality rates.
Abstract Nonvolatile, ion‐dense electrolytes, such as ionic liquids and deep eutectic solvents (DESs) are attractive candidates for safe, high‐performance electrochemical/electrostatic energy storage devices. In this report, an inexpensive eco‐friendly DES (1 : 2 mixture of choline chloride/ethylene glycol) has been incorporated into a solid‐state gel electrolyte using chemically cross‐linked polymer scaffold formed through in situ UV copolymerization 2‐hydroxyethyl methacrylate (HEMA)...
Discharge of antibiotic-containing wastewater causes environmental pollution and threatens biological human health. An efficient treatment method for this is urgently required. We prepared inorganic-organic hybrid MXene-pillararene nanosheets with a large lateral size (5-8 μm). The were stacked on supports via vacuum-assisted filtration to prepare membranes regular parallel slits an interlayer spacing 1.36 nm, which used purify water. Permeance through the membrane increased 100-fold...
Photoacoustic imaging (PAI) and photoacoustic (PA) therapy have promising applications for treating tumors. It is known that the utilization of high‐absorption‐coefficient probes can selectively enhance PAI target contrast PA tumor efficiency in deep‐seated tissue. Here, design a probe with highest availability optical‐thermo conversion by using graphene oxide (GO) dyes via π–π stacking interactions reported. The GO serves as base material loading quenching dye fluorescence resonance energy...
Grb2-associated binder 2 (Gab2), a scaffolding adaptor protein, has recently been implicated in cancer progression. However, the role of Gab2 progression and metastasis colorectal (CRC) remains unclear. expression was assessed CRC patient specimens as well cell lines. Recombinant lentivirus vector containing gene its small interfering RNAs were constructed introduced into cells. Cell migration invasion ability evaluated by transwell assays vitro, vivo performed on nude mice model. Moreover,...
The distinctive role of Yes-associated protein (YAP) in the nervous system has attracted widespread attention. This comprehensive review strategically uses retina as a vantage point, embarking on an extensive exploration YAP's multifaceted impact from to brain development and pathology. Initially, we explore crucial roles YAP embryonic cerebral development. Our focus then shifts retinal development, examining detail regulatory influence pigment epithelium (RPE) progenitor cells (RPCs), its...
One of the features high-risk atherosclerotic plaques is preponderance macrophages. Gadolinium(III)-gold nanorods (Gd(III)-GNRs) have been developed as a dual-modality probe for MRI and photoacoustic imaging (PAI) to trace macrophages determining degree inflammation.Gd(III)-GNRs were utilized PAI detection in living mice ex vivo simulated macrophage-rich plaque.Gd(III)-GNRs shown be endocytosed by vitro. Macrophages labeled with Gd(III)-GNRs detected both MRI. With Gd(III)-GNRs, it possible...
Abstract Glioblastoma is an extremely difficult clinical indication with very few therapeutic choices. In this study, a nanoparticle constructed featuring high red absorbance and selective penetration of the blood–brain barrier (BBB) at tumor site. This can provide timely activation adenosine receptor on BBB to allow self‐passage accumulation in tumor. The converts pulsed laser energy into shockwave via photoacoustic (PA) cavitation achieve localized mechanical damage thus yields precision...
Abstract Discharge of antibiotic‐containing wastewater causes environmental pollution and threatens biological human health. An efficient treatment method for this is urgently required. We prepared inorganic–organic hybrid MXene–pillararene nanosheets with a large lateral size (5–8 μm). The were stacked on supports via vacuum‐assisted filtration to prepare membranes regular parallel slits an interlayer spacing 1.36 nm, which used purify water. Permeance through the membrane increased...
Fast focusing scan over a large depth range is challenging in photoacoustic microscopic imaging. In this paper, fast variable focus microscopy (VF-PAM) with of imaging was presented by using an electrically tunable lens (ETL). The ETL controlled the divergence angle laser beam for and continuous focus-shifting direction shifting time 15 ms, 2.82 mm 1 µm accuracy achieved combining 0.3 NA plan microscope objective lens. Carbon fibers verified ability system, vivo microvasculature mouse ear...
The development of functional nanomaterials that undergo renal clearance is fundamental importance to their in vivo biomedical applications. In this work, we report a one-pot method for the preparation ultrasmall copper sulfide nanodots capped with small natural tripeptide glutathione (GSH-CuS NDs). GSH-CuS NDs had hydrodynamic diameter 5.8 nm, smaller than reported polymer-coated CuS similar core sizes, and exhibited strong optical absorption conversion at near-infrared (NIR) region,...
Cancer stem cells (CSCs) are largely responsible for tumor relapse and metastatic behavior. Doublecortin-like kinase 1 (DCLK1) was recently reported to be a biomarker gastrointestinal CSCs involved in the epithelial-mesenchymal transition (EMT) progression. B cell-specific Moloney murine leukemia virus insertion site (Bmi-1) is crucial regulator of CSC self-renewal, malignant transformation EMT, previous study from our group showed that Bmi-1 upregulated pancreatic cancer progression...