A5064248231- Dermatology and Skin Diseases
- Urticaria and Related Conditions
- Vascular Malformations Diagnosis and Treatment
- Allergic Rhinitis and Sensitization
- Vascular Malformations and Hemangiomas
- Stress Responses and Cortisol
- Polyomavirus and related diseases
- Advancements in Transdermal Drug Delivery
- Nerve injury and regeneration
- Ion Channels and Receptors
- Noise Effects and Management
- Nicotinic Acetylcholine Receptors Study
- Planarian Biology and Electrostimulation
- Air Quality and Health Impacts
- Genital Health and Disease
- Ion channel regulation and function
- Tissue Engineering and Regenerative Medicine
- Inflammasome and immune disorders
- Herpesvirus Infections and Treatments
- Neuroscience and Neuropharmacology Research
- SARS-CoV-2 and COVID-19 Research
- Vascular Tumors and Angiosarcomas
- Hereditary Neurological Disorders
- Pluripotent Stem Cells Research
- Lipid Membrane Structure and Behavior
Université de Bretagne Occidentale
2016-2024
Laboratoire des Sciences et Techniques de l’Information de la Communication et de la Connaissance
2022
Laboratoire Léon Brillouin
2022
CEA Paris-Saclay
2022
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2022
Centre Hospitalier Régional Universitaire de Brest
2019
Cliniques Universitaires Saint-Luc
2006-2016
UCLouvain
1994
Skin-derived precursor cells (SKPs) are neural crest stem that persist in certain adult tissues, particularly the skin. They can generate a large type of cell vitro, including neurons. SKPs were induced to differentiate into sensory neurons (SNs) by molecules previously shown be important for generation SNs: purmorphamine, CHIR99021, BMP4, GDNF, BDNF, and NGF. We showed differentiation upregulation neurogenins. At end protocol, transcriptional analysis was performed on BRN3A marker...
Itch is a common sensation which amenable to disabling patients' life under pathological and chronic conditions. Shared assertion easily limits itch chemical itch, without considering mechanical alloknesis, its counterpart. However, in recent years, our understanding of the pathway, particularly central nervous system, has been enhanced. In addition, Merkel complexes, conventionally considered as tactile end organs only responsible for light touch perception due Piezo2 expressed by both...
Skin, and epidermis, is innervated by sensory nerve fibres. Interactions between them signal transduction are only partially elucidated in physiological/pathological conditions, especially pruritus.To study the mechanisms involved pruritus vitro, we developed a skin explant model re-innervated neurons.This based on co-culture of human explants neurons from dorsal root ganglia rats. Innervation expression protease activated receptor 2 (PAR2), transient potential vanilloid 1 (TRPV1) ankyrin...
Abstract The effects of air pollution on health are gaining increasing research interest with limited data skin alterations available. It was suggested that is a trigger factor for sensitive (SS). However, this based surveys lack experimental data. SS related to altered nerve endings and cutaneous neurogenic inflammation. TTe present study assess the in vitro effect particulate matter (PM) epidermis ending homeostasis. PM samples were collected according validated protocol. Reconstructed...
The concept of pseudo-factitial dermatitis can be defined as follows: any skin condition which, by its clinical or histopathological profile, lead the clinician to an erroneous diagnosis factitial dermatitis. Therefore, does not exist such; intellectually, it is special interest for practising dermatologist, in terms differential diagnosis, either histopathological.