A5100755145- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- SARS-CoV-2 and COVID-19 Research
- Analytical Methods in Pharmaceuticals
- SARS-CoV-2 detection and testing
- Nanoparticle-Based Drug Delivery
- Advancements in Transdermal Drug Delivery
- Analytical Chemistry and Chromatography
- Hydrogels: synthesis, properties, applications
- Protein purification and stability
- Animal Virus Infections Studies
- Amoebic Infections and Treatments
- Virology and Viral Diseases
- Parasitic Diseases Research and Treatment
- COVID-19 epidemiological studies
- Lipid Membrane Structure and Behavior
- Healthcare and Venom Research
- Maternal and fetal healthcare
- Ectopic Pregnancy Diagnosis and Management
- Dendrimers and Hyperbranched Polymers
- Vaccine Coverage and Hesitancy
- Berberine and alkaloids research
- COVID-19 Impact on Reproduction
- Polymer Surface Interaction Studies
- Microbial infections and disease research
Korea Disease Control and Prevention Agency
2021-2024
CHA University
2023
Ewha Womans University Medical Center
2022
Seoul National University
2022
University College London
2022
Korea Center for Disease Control and Prevention
2022
Chungnam National University
2004-2019
National Veterinary Research and Quarantine Service
2009
Inje University
2008
Abstract To clarify transmissibility of the severe acute respiratory syndrome coronavirus 2 Omicron variant, we determined serial intervals and secondary attack rates among household contacts in South Korea. Mean interval for 12 transmission pairs was 2.9 days, rate 25 households 50.0%, raising concern about a rapid surge cases.
In November 2021, 14 international travel-related severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 (omicron) variant of concern (VOC) patients were detected in South Korea. Epidemiologic investigation revealed community transmission the omicron VOC. A total 80 SARS-CoV-2 VOC-positive identified until December 10, 2021 and 66 them reported no relation to travel. There may be more transmissions with this VOC Korea than reported.
The purpose of this study was to develop a buccal paclitaxel delivery system using the thermosensitive polymer Pluronic F127 (PF127) and mucoadhesive polyethylene oxide (PEO). anticancer agent is usually used treat ovarian, breast, non-small-cell lung cancer. To improve its aqueous solubility, incorporated into an inclusion complex with (2,6-di-O-methyl)-β-cyclodextrin (DMβCD). formation evaluated various techniques, including x-ray diffractometry (XRD), Fourier-transform infrared (FT-IR)...
The objective of this study was to improve the solubility albendazole and optimize preparation an oral nanoparticle formulation, using β-cyclodextrin (βCD) chitosan-tripolyphosphate (TPP) nanoparticles. in buffers, surfactants, various concentrations acetic acid solution investigated. To determine drug loading, cytotoxic effects concentration human hepatocellular carcinoma cells (HepG2) were formulations prepared by mixing Tween 20 with chitosan solution. TPP added dropwise sonication...
This study was performed to compare acid-phosphatase staining with polymerase chain reaction (PCR) analysis for the diagnosis of Dirofilaria repens infection. The infection D. confirmed in Korean reared German shepherd dogs. Knott's tests were carried out detection microfilaria 543 dogs (255 females and 288 males). Eighty four (15.5%) showed microfilaria-positive reactions modified test, test-positive microfilariae then examined by both acid phosphatase PCR analysis. Six (7.1%) 17 (20.2%) 84...
Abstract Enzyme-linked immunosorbent assay (ELISA) has been developed as the ancillary diagnosis of bovine tuberculosis at ante-mortem to overcome disadvantages intradermal skin test. In this study, antigenic proteins were purified, applied bTB ELISA, and identified through proteomic analysis. Culture filtrate protein Mycobacterium bovis was fractionated by MonoQ® column chromatography, examined antigenicity immunoblotting. The 20 kDa in-gel digested antigenome LTQ® mass spectrometer peptide...
Abstract As the coronavirus disease 2019 (COVID‐19) pandemic continues, reinfection is likely to become increasingly common. However, confirming COVID‐19 difficult because it requires whole‐genome sequencing of both infections identify degrees genetic differences. Since first reported case severe acute respiratory syndrome 2 (SARS‐CoV‐2) in Republic Korea April 2020, four additional cases were classified as suspected cases. We performed viral RNA extracted from swabs obtained at initial...
This study aimed to describe the characteristics and risk factors for severe disease in pregnant women infected with coronavirus 2019 (COVID-19) from early days of COVID-19 epidemic Korea predominant period Delta variant.