A5002850853- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Polymer Surface Interaction Studies
- Titanium Alloys Microstructure and Properties
- Orthopaedic implants and arthroplasty
- 3D Printing in Biomedical Research
- Graphene and Nanomaterials Applications
- Neuroscience and Neural Engineering
- Tissue Engineering and Regenerative Medicine
- Nanofabrication and Lithography Techniques
- Anodic Oxide Films and Nanostructures
- Hemostasis and retained surgical items
- Surface Modification and Superhydrophobicity
- Nanocomposite Films for Food Packaging
- Marine Biology and Environmental Chemistry
- Metal and Thin Film Mechanics
- Additive Manufacturing and 3D Printing Technologies
- Dental materials and restorations
- Antimicrobial agents and applications
- biodegradable polymer synthesis and properties
- Cardiac Valve Diseases and Treatments
- Advanced Sensor and Energy Harvesting Materials
- Orthopedic Infections and Treatments
- Force Microscopy Techniques and Applications
- Wound Healing and Treatments
Colorado State University
2016-2025
George Mason University
2024-2025
Universidade Federal de Itajubá
2020
University of Colorado Boulder
2020
University of Florida
2019
University of California, San Francisco
2006-2017
North Carolina State University
2016
University of Portsmouth
2016
Clemson University
2016
Seoul National University
2016
We report for the first time fabrication of self-aligned hexagonally closed-packed titania nanotube arrays over 1000 μm in length and aspect ratio ≈10 000 by potentiostatic anodization titanium. describe a process which such thick array films can be transformed into self-standing, flat or cylindrical, mechanically robust, polycrystalline TiO2 membranes precisely controlled nanoscale porosity. The self-standing are characterized using Brunauer−Emmett−Teller surface area measurements, glancing...
A biosensor application of vertically coupled glass microring resonators with Q/spl sim/12 000 is introduced. Using balanced photodetection, very high signal to noise ratios, and thus sensitivity refractive index changes (limit detection 1.8/spl times/10/sup -5/ units), are achieved. Ellipsometry X-ray photoelectron spectroscopy results indicate successful modification surfaces. Experimental data obtained separately for a bulk change the medium avidin-biotin binding on ring surface reported....
Nanotubes for drug release: Titania nanotubes (see image) fabricated by an easy anodization process can be used as drug-eluting coatings implantable devices. The release rate of the drugs is controlled varying amount proteins loaded into nanotubes. Moreover, changing nanotube diameter, wall thickness, and length, kinetics altered each specific to achieve a sustained release.
Chemical modification of polysaccharides is an important route to enhance, develop or change polysaccharide properties. In this study, carboxymethylation kappa-carrageenan (KC) with monochloroacetic acid was performed achieve different degrees substitution (DS) carboxymethyl-kappa-carrageenan (CMKC). The degree ranged from 0.8 1.6 and calculated the 1H NMR spectra. chemical structure CMKCs further characterized by FT-IR, 13C NMR. FT-IR confirmed carboxymethylation. Carboxymethylation...
The periosteum is a membrane that surrounds bones, providing essential cellular and biological components for fracture healing bone repair. Tissue engineered scaffolds able to function as substitutes can significantly improve regeneration in severely injured tissues. Efforts develop more bioactive tunable periosteal are required the success of this tissue engineering approach. In work, chemical modification was performed chitosan, polysaccharide with osteoconductive properties, by...
Abstract Micro/nano scale surface modifications of titanium based orthopedic and cardiovascular implants has shown to augment biocompatibility. However, bacterial infection remains a serious concern for implant failure, aggravated by increasing antibiotic resistance over usage antibiotics. Bacteria cell adhesion on leads colonization biofilm formation resulting in morbidity mortality. Hence, there is need develop new surfaces with high antibacterial properties. Recent developments have that...
Nanoporous alumina surfaces have a variety of applications in biosensors, biofiltration, and targeted drug delivery. However, the fabrication route to create these nanopores results surface defects crystal lattice. This inherent charge on porous causing biofouling, that is, nonspecific adsorption biomolecules. Poly(ethylene glycol) (PEG) is known form biocompatible nonfouling films silicon surfaces. its application very limited has not been well investigated. In this study, we covalently...
Abstract A major goal in orthopedic biomaterials research is to design implant surfaces, which will enhance osseointegration vivo . Several microscale as well nanoscale architectures have been shown significantly affect the functionality of bone cells i.e., osteoblasts. In this work, nanoporous alumina surfaces fabricated by a two‐step anodization process were used. The nanostructure these can be controlled varying voltage used for process. Marrow stromal isolated from mice and seeded on...
Abstract An understanding of osteoblast response to surface topography is essential for successful bone tissue engineering applications. Alumina has been extensively used as a substrate constructs. However, current techniques do not allow precise and orientation the material. In this research, two‐step anodization process was optimized fabrication nanoporous alumina membranes with uniform pore dimension distribution. The voltage can be varied create sizes ranging from 30 80 nm in diameter....
Abstract Hemocompatibility is a key consideration for the long‐term success of blood contacting biomaterials; hence, there critical need to understand physiological response elicited from blood/nano–biomaterial interactions. In this study, we have investigated adsorption serum proteins, in vitro adhesion and activation platelets, clotting kinetics whole on titania nanotube arrays. Previous studies demonstrated improved mesenchymal stem cell functionality, osteoblast phenotypic behavior,...