A5024736595- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Neuroinflammation and Neurodegeneration Mechanisms
- Traumatic Brain Injury Research
- Cerebrospinal fluid and hydrocephalus
- Spinal Cord Injury Research
- Intensive Care Unit Cognitive Disorders
- Alzheimer's disease research and treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Palliative Care and End-of-Life Issues
- Nerve injury and regeneration
- Mesenchymal stem cell research
- Disaster Response and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Sphingolipid Metabolism and Signaling
- Cerebral Venous Sinus Thrombosis
- Heart Rate Variability and Autonomic Control
- Trauma and Emergency Care Studies
- Neurogenesis and neuroplasticity mechanisms
- Cardiac Ischemia and Reperfusion
- Organ Donation and Transplantation
- Thermal Regulation in Medicine
- EEG and Brain-Computer Interfaces
- Neurological Disease Mechanisms and Treatments
- Neurosurgical Procedures and Complications
University of Maryland, Baltimore
2020-2022
Columbia University
2021
New York College of Health Professions
2021
The pathological process of traumatic spinal cord injury (SCI) involves excessive activation microglia leading to the overproduction proinflammatory cytokines and causing neuronal injury. Sphingosine kinase 1 (Sphk1), a key enzyme responsible for phosphorylating sphingosine into sphingosine-1-phosphate (S1P), plays an important role in mediating inflammation, cell proliferation, survival, immunity.We aim investigate mechanism pathway Sphk1-mediated neuroinflammatory response rodent model...
Jia, Xiaofeng; Wang, Zhuoran; Zhang, Shuai; Du, Jian; Chen, Songyu; Lachance, Brittany Author Information