A5030752781- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Liver Diseases and Immunity
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
Loma Linda University
2016-2020
Loma Linda University Medical Center
2016-2020
Huntington Medical Research Institutes
2006-2007
Background & AimsCaspase-mediated apoptosis and inflammation contribute to progression of liver disease. Emricasan is a pan-caspase inhibitor that reduced serum markers in patients with hepatitis C non-alcoholic steatohepatitis (NASH).MethodsWe performed multicenter study 86 cirrhosis (Child-Pugh class A or B; mean score, 6.9; 38% alcohol-associated cirrhosis, 29% HCV-associated 23% NASH) model for end-stage disease (MELD) scores 11–18 (mean, 12.8). Patients were randomly assigned groups...
Chronic hepatitis B virus (HBV) infection is associated with hepatocellular carcinoma (HCC), and specific viral factors have been identified that may increase the risk for HCC development. However, differences in these chronic carriers who seldom develop compared patients not adequately evaluated.From 1989 to 2005, 101 surface antigen-positive presented our clinic HCC. Baseline basal core promoter (BCP) T1762/A1764 mutants, precore (PC) A1896 HBV genotypes DNA were 67 had followed a mean of...
OBJECTIVES To study the demographics, epidemiology, and natural history of chronic hepatitis C in Asian Americans. METHODS This retrospective survey describes 260 Americans with referred to one tertiary center. RESULTS Ninety-two percent patients were born Asia. Fifty-one reported a unsafe therapeutic injections, which was risk factor only those exposure outside United States (p < 0.0001). A transfusion 41% more frequent within Unites Only 3.8% intravenous drug abuse, Hepatitis genotype 1...
Multi-phase computed tomography (CT) or magnetic resonance imaging (MRI) has been the standard of care for hepatocellular carcinoma (HCC) diagnosis years.We report a case series four patients in whom positron emission tomography-computed (PET-CT) scan complemented conventional CT/MRI scans evaluating treatment response. In these cases multi-phase CT and MRI failed to identify residual HCC disease post-treatment, while PET-CT aided response evaluation. each case, addition identified located...