A5005427020- Neutrino Physics Research
- Particle physics theoretical and experimental studies
- Astrophysics and Cosmic Phenomena
- Epigenetics and DNA Methylation
- Acute Myeloid Leukemia Research
- RNA modifications and cancer
- Diversity and Career in Medicine
- COVID-19 and healthcare impacts
- Immunotherapy and Immune Responses
- Global Cancer Incidence and Screening
- COVID-19 Clinical Research Studies
- Innovations in Medical Education
- Cancer-related molecular mechanisms research
- Surgical Simulation and Training
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Immunotherapy and Biomarkers
- Hospital Admissions and Outcomes
- Breast Cancer Treatment Studies
- Chronic Myeloid Leukemia Treatments
- CAR-T cell therapy research
- Gastric Cancer Management and Outcomes
- Cutaneous Melanoma Detection and Management
- Algal biology and biofuel production
- Virus-based gene therapy research
- Advances in Oncology and Radiotherapy
Loma Linda University
2016-2025
Jacksonville College
2025
Mayo Clinic in Florida
2025
VA Loma Linda Healthcare System
2016-2024
Loma Linda University Medical Center
2014-2023
Emory University
2023
Royal Manchester Children's Hospital
2023
Jerry L. Pettis Memorial VA Medical Center
2023
Tenwek Hospital
2022
Loma Linda University Health Care
2010-2022
Patients with cancer may be at high risk of adverse outcomes from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We analyzed a cohort patients and 2019 (COVID-19) reported to the COVID-19 Cancer Consortium (CCC19) identify prognostic clinical factors, including laboratory measurements anticancer therapies. active or historical laboratory-confirmed SARS-CoV-2 diagnosis recorded between 17 March 18 November 2020 were included. The primary outcome was severity measured...
Dendritic cells (DCs) are bone marrow-derived leukocytes that function as potent antigen presenting capable of initiating T cell-dependent responses from quiescent lymphocytes. DC pulsed with tumor-associated (TAA) peptide or protein have recently been demonstrated to elicit antigen-specific protective antitumor immunity in a number murine models. Transduction DCs TAA genes may allow stable, prolonged expression well the potential for presentation multiple, unidentified, epitopes association...
We sought to determine whether US Medical Licensing Examination (USMLE) Step 1 score, American Board of Surgery (ABS) In-Training (ABSITE) and other variables are associated with failing the ABS qualifying certifying examinations. Identifying such factors may assist in early implementation an academic intervention for at-risk residents.Retrospective review.Seventeen general surgery training programs western United States.Six hundred seven residents who graduated 2000-2007.First-time pass...
General surgical residency continues to experience attrition. To date, work hour amendments have not changed the annual rate of attrition.To determine how often categorical general surgery residents seriously consider leaving residency.At 13 programs, an anonymous survey 371 and 10-year attrition rates for each program. Responses from those who considered were compared with did not.Factors associated desire leave residency.The response was 77.6%. Overall, 58.0% training. The most frequent...
This study compares survival rates, recurrence patterns, toxicity, and treatment cost in patients with hepatocellular carcinoma (HCC) treated either transarterial chemoembolization (TACE) or proton beam radiotherapy (PBT).Subjects untreated HCC meeting Milan San Francisco transplant criteria were recruited. Subjects randomized to receive PBT (n = 36) TACE 40). Proton therapy was administered 15 fractions over 3 weeks a total dose of 70.2 Gy. repeated until complete maximal response. The...
Pseudomonas aeruginosa strain CSU, a nongenetically engineered bacterial known to bind dissolved hexavalent uranium (as UO(2) (2+) and/or its cationic hydroxo complexes), was characterized with respect sorptive activity (equilibrium and dynamics). Living, heat-killed, permeabilized, unreconstituted lyophilized cells were all capable of binding uranium. The biosorption equilibrium could be described by the Langmuir isotherm. rate adsorption increased following permeabilization outer...
RASSF1C up-regulates important genes involved in lung cancer cell growth, including a stem self-renewal gene, piwil1. In this article, we report the identification of small noncoding PIWI-interacting RNAs (piRNAs) cells over-expressing RASSF1C. A piRNA microarray screen was performed using RNA isolated from line H1299 stably and corresponding control. The identified several piRNAs that are regulated by have validated expression two up-regulated (piR-34871 piR-52200) down-regulated (piR-35127...
Pseudomonas aeruginosa CSU, a nongenetically engineered bacterial strain previously shown to bind dissolved hexavalent uranium (as UO22+ and/or its cationic hydroxy complexes), shows promise as the basis of an immobilized-cell process for removal from contaminated wastewaters. A number polymeric materials, including calcium alginate, polyacrylamide, polysulfone, and polyurethane, were evaluated possible immobilization matrices lyophilized biomass P. CSU. Polyurethane-based materials such...
The T2K experiment studies oscillations of an off-axis muon neutrino beam between the J-PARC accelerator complex and Super-Kamiokande detector. Special emphasis is placed on measuring mixing angle theta_13 by observing electron appearance via sub-dominant to oscillation, searching for CP violation in lepton sector. includes a sophisticated, off-axis, near detector, ND280, situated 280 m downstream production target order measure properties understand better interactions at energy scale below...
<h3>Objective</h3>To determine the rates and predictors of remediation attrition among general surgery residents.<h3>Design, Setting, Participants</h3>Eleven-year retrospective analysis 348 categorical residents at 6 West Coast programs.<h3>Main Outcome Measures</h3>Rates attrition.<h3>Results</h3>Three hundred forty-eight were included. One seven (31%) required remediation, which 27 remediated more than once. Fifty-five (15.8%) left their programs, although only 2 owing to failed...
The 80-hour work-week limit for all residents was instituted in 2003 and studies looking at its effect have been mixed. Since the advent of 16-hour mandate postgraduate year 1 July 2011, no data published regarding this additional work-hour restriction.To determine whether intern work limit, implemented has adversely affected operative experience.A retrospective review categorical Accreditation Council Graduate Medical Education case logs from class (N = 52) (with limit) compared with 4...
<h3>Importance</h3> In general surgery, women earn less money and hold fewer leadership positions compared with their male counterparts. <h3>Objective</h3> To assess whether differences exist between the perspectives of female surgery residents on future career goals, salary expectations, negotiation that may contribute to disparity later in careers. <h3>Design, Setting, Participants</h3> This study was based an anonymous voluntary survey sent 19 US programs. A total 606 categorical at...
Abstract Background Perry syndrome (PS) is a rare and fatal hereditary autosomal dominant neurodegenerative disorder caused by mutations in dynactin ( DCTN1 ). PS brains accumulate inclusions positive for ubiquitin, transactive‐response DNA‐binding protein of 43 kDa (TDP‐43), to lesser extent dynactin. Objectives Little known regarding the contributions TDP‐43, an RNA binding that represses cryptic exon inclusion, PS. Therefore, we sought identify degree TDP‐43 dysfunction two regions...
Biologic therapy (BT) (eg, bevacizumab or cetuximab) is increasingly used to treat metastatic colorectal cancer (mCRC). Recent investigations have suggested that right- left-sided primary tumor origin affects survival and response BT.To evaluate the association of with mortality in a diverse population-based data set patients receiving systemic chemotherapy (SC) cetuximab for mCRC.This nonconcurrent cohort study statewide California Cancer Registry included all aged 40 85 years diagnosed...