A5078397712- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Economic and Financial Impacts of Cancer
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Global Cancer Incidence and Screening
- Pulmonary Hypertension Research and Treatments
- Cancer Genomics and Diagnostics
- 2D Materials and Applications
- Healthcare cost, quality, practices
- Advanced Breast Cancer Therapies
- Renin-Angiotensin System Studies
- Radiomics and Machine Learning in Medical Imaging
- Graphene research and applications
- Social Media in Health Education
- scientometrics and bibliometrics research
- Microbial Natural Products and Biosynthesis
- MXene and MAX Phase Materials
- Electronic and Structural Properties of Oxides
- Microbial Metabolism and Applications
- Cardiovascular Issues in Pregnancy
- Infection Control and Ventilation
- Cardiovascular Function and Risk Factors
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
Hainan University
2024
First Affiliated Hospital of Guangzhou Medical University
2022-2024
State Key Laboratory of Respiratory Disease
2022-2024
Guangzhou Medical University
2022-2024
National Clinical Research
2024
Vanderbilt University Medical Center
2022-2024
University of California, San Diego
2024
Peking University
2023
China Medical University
2023
Institute of Physics
2019-2023
Patients with cancer may be at high risk of adverse outcomes from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We analyzed a cohort patients and 2019 (COVID-19) reported to the COVID-19 Cancer Consortium (CCC19) identify prognostic clinical factors, including laboratory measurements anticancer therapies. active or historical laboratory-confirmed SARS-CoV-2 diagnosis recorded between 17 March 18 November 2020 were included. The primary outcome was severity measured...
Two-dimensional topological materials have attracted intense research efforts owing to their promise in applications for low-energy, high-efficiency quantum computations. Group-VA elemental thin films with strong spin–orbit coupling been predicted host topologically nontrivial states as excellent two-dimensional materials. Herein, we experimentally demonstrated the first time that epitaxially grown high-quality antimonene monolayer islands buckled configurations exhibit significantly robust...
Abstract The lattice geometry induced second-order topological corner states in breathing Kagome have attracted enormous research interests, while the realistic materials identified as insulators are still lacking. Here, we report by first-principles calculations emerging two-dimensional d -orbital crystals, i.e., monolayer niobium/tantalum chalcogenide halides M 3 QX 7 (M = Nb, Ta; Q S, Se, Te; X Cl, Br, I). We find that orbital degree of freedom orbitals can give rise to multiple sets...
Patients with B-lymphoid malignancies have been consistently identified as a population at high risk of severe COVID-19. Whether this is exclusively due to cancer-related deficits in humoral and cellular immunity, or whether COVID-19 increased by anticancer therapy, uncertain. Using data derived from the Cancer Consortium (CCC19), we show that patients treated for an compared control populations non-B-lymphoid malignancies. Among malignancies, those who received therapy within 12 months...
Charge density wave (CDW) strongly affects the electronic properties of two-dimensional (2D) materials and can be tuned by phase engineering. Among 2D transitional metal dichalcogenides (TMDs), VTe 2 was predicted to require small energy for its transition shows unexpected CDW states in T-phase. However, state H-VTe has been barely reported. Here, we investigate monolayer (ML) , induced phase-engineering from T-phase . The between T- is revealed with x-ray photoelectron spectroscopy (XPS)...
Chronic kidney disease (CKD) is a significant risk factor for pulmonary hypertension (PH), complication that adversely affects patient prognosis. However, the mechanisms underlying this association remain poorly understood. A major obstacle to progress in field lack of reliable animal model replicating CKD-PH. This study aimed establish stable rat We employed combined approach, inducing CKD through 5/6 nephrectomy and concurrently exposing rats high-salt diet. The model's hemodynamics were...
Aim: CDK4/6 have critical roles in the early stage of cell cycle. CDK2 acts later cycle and has a considerably broader range protein substrates, some which are essential for normal proliferation. Therefore, increasing selectivity cyclin-dependent kinase (CDK) inhibitors is critical. Methodology: In this study, we construct versatile, specific CDK4 pharmacophore model that not only matches well with 8119 reported 9349 but also differentiates from pharmacophore. Results & Conclusion:...
Pregnant women with pulmonary hypertension (PH) have higher mortality rates and poor foetal/neonatal outcomes. Tools to assess these risk factors are not well established.Predictive prognostic nomograms were constructed using data from a "Development" cohort of 420 pregnant patients PH, recorded between January 2009 December 2018. Logistic regression analysis established models predict the probability adverse maternal events overall survival by Cox analysis. An independent "Validation"...
Real-space access of the orbital degree freedom in complex oxides is still challenging due to intricate electronic hybridization. Here, we report a direct observation reproducible orbital-selective tunneling on novel SrTiO3(001) surface by scanning microscopy. The structures reversibly switch between two different sets symmetries depending sample bias, which accompanied remarkable change energy-dependent spectroscopy data. Tunneling spectrum combined with density functional theory...
In this study, chemical profiles for two co-existing deep-sea-derived Penicillium fungal strains were thoroughly investigated. Two new compounds and 11 known identified from sp. LXY140-R, while one compound 12 isolated LXY140-3. Their structures elucidated by extensive 1D 2D NMR experiments, which supported HR-ESI-MS data. The antiproliferative activities of all isolates against HCT-116, A549 Bel-7402 cell lines also evaluated. Compounds 2, 5, 6, 10 13 showed potent activity. To reveal the...
Abstract Introduction COVID-19 particularly impacted patients with co-morbid conditions, including cancer. Patients melanoma have not been specifically studied in large numbers. Here, we sought to identify factors that associated severity among melanoma, assessing outcomes of on active targeted or immune therapy. Methods Using the and Cancer Consortium (CCC19) registry, identified 307 diagnosed COVID-19. We used multivariable models assess demographic, cancer-related, treatment-related a...
Under the global aging trend, re-employment of elderly has become a hot topic full controversy. This paper uses case study method to influence on mental health and finds that benefits elderly. On one hand, can subsidize family expenditures through re-employment. They do not want be burden their children best for family. other older adults also yearn better life. hope obtain higher incomes, meet consumption demands, realize self-worth spiritual satisfaction Therefore, society must more open,...
Background: More than 50% of patients with lung cancer are admitted to the hospital while receiving treatment, which is a burden and healthcare system. This study characterizes risk factors outcomes who were hospital. Methods: A multidisciplinary oncology care team conducted retrospective medical record review in 2018. Demographics, disease admission characteristics, end-of-life utilization recorded. Following consensus process, admissions determined be either “avoidable” or “unavoidable.”...
Background: Limited information is available for patients with breast cancer (BC) and coronavirus disease 2019 (COVID-19), especially among underrepresented racial/ethnic populations. Methods: This a COVID-19 Cancer Consortium (CCC19) registry-based retrospective cohort study of females active or history BC laboratory-confirmed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection diagnosed between March 2020 June 2021 in the US. Primary outcome was severity measured on...
Abstract Clinical trials establish the standard of cancer care, yet evolution and characteristics social dynamics between people conducting this work remain understudied. We performed a network analysis authors publishing chemotherapy-based prospective from 1946 to 2018 understand how influences, including role gender, have influenced growth development network, which has expanded exponentially fewer than 50 in 29,197 2018. While 99.4% were directly or indirectly connected by 2018, our...
Abstract Background Pulmonary hypertension (PH) is a common complication in patients with chronic kidney disease (CKD), affecting prognosis. However, the pathogenesis not clear, and lack of stable animal model significant factor. Methods In this study, rat pulmonary (CKD-PH) was developed through 5/6 nephrectomy combined high-salt diet. The model’s hemodynamics pathological changes multiple organs were dynamically assessed. Lung tissues serum collected from rats to measure expression ACE2,...
Abstract Background： Pulmonary hypertension (PH) is a common complication in patients with chronic kidney disease (CKD), affecting prognosis. However, the pathogenesis not clear, and lack of stable animal model significant factor. Methods： In this study, rat pulmonary (CKD-PH) was developed through 5/6 nephrectomy combined high-salt diet. The model's hemodynamics pathological changes multiple organs were dynamically assessed. Lung tissues serum collected from rats to measure expression ACE2,...
<title>Abstract</title> With the rapid advancement of artificial intelligence (AI) and deep learning, AI-driven models are increasingly being used in medical field for disease classification diagnosis. However, robustness these against adversarial attacks is a critical concern, as such can significantly distort diagnostic outcomes, leading to potential clinical errors. This study investigates various convolutional neural network (CNN) models, including MobileNet, Resnet-152, Vision...