A5019561301- Thyroid and Parathyroid Surgery
- Parathyroid Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Pituitary Gland Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Hormonal Regulation and Hypertension
- Clinical practice guidelines implementation
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- Genetic Syndromes and Imprinting
- Head and Neck Anomalies
- Neuroblastoma Research and Treatments
- Global Healthcare and Medical Tourism
- COVID-19 and healthcare impacts
- Cancer Diagnosis and Treatment
- Sympathectomy and Hyperhidrosis Treatments
- Angiogenesis and VEGF in Cancer
- Lung Cancer Research Studies
- Multiple and Secondary Primary Cancers
- Glioma Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Cardiac, Anesthesia and Surgical Outcomes
- Laser Applications in Dentistry and Medicine
- COVID-19 Clinical Research Studies
Vanderbilt University Medical Center
2016-2025
Nashville Oncology Associates
2024
Vanderbilt University
2015-2024
Northwestern University
2018-2024
Hudson Institute
2024
Indianapolis Zoo
2024
West Los Angeles College
2024
Jackson College
2024
Kaiser Permanente Fontana Medical Center
2024
Ann Arbor Center for Independent Living
2024
Primary hyperparathyroidism (pHPT) is a common clinical problem for which the only definitive management surgery. Surgical has evolved considerably during last several decades.To develop evidence-based guidelines to enhance appropriate, safe, and effective practice of parathyroidectomy.A multidisciplinary panel used PubMed review medical literature from January 1, 1985, July 2015. Levels evidence were determined using American College Physicians grading system, recommendations discussed...
Abstract IL-1alpha and IL-1beta are potent inflammatory cytokines that contribute to a number of normal physiologic processes the development diseases. Two IL-1R, type I II receptors, have been identified. This work describes derivation characterization mice deficient in expression IL-1R (IL-1RI). IL-1RI-deficient were viable fertile, but failed respond IL-1 variety assays, including IL-1-induced IL-6 E-selectin fever. Similar IL-1beta-deficient mice, had reduced acute phase response...
Progress in the diagnosis, localization of abnormal parathyroids, and intraoperative management primary hyperparathyroidism has been observed over past 34 years. The goal this study is to report outcome patients undergoing 2 different operative approaches a single institution, showing evolution surgical sporadic (SPHPT).Parathyroidectomy was performed 890 (827 initial, 63 reoperative) with SPHPT using approaches: traditional bilateral neck exploration (BNE, n = 396) or limited...
The inability to accurately localize the parathyroid glands during parathyroidectomy and thyroidectomy procedures can prevent patients from achieving postoperative normocalcemia. There is a critical need for an improved intraoperative method real-time identification.The objective of study was test accuracy real-time, label-free technique that uses near-infrared (NIR) autofluorescence imaging parathyroid.The conducted at Vanderbilt University endocrine surgery center.Patients undergoing...
Adrenocortical carcinoma (ACC) is a rare but aggressive endocrine tumor, and the prognostic factors associated with long-term outcomes after surgical resection remain poorly defined.To define clinicopathological variables recurrence-free survival (RFS) overall (OS) curative of ACC to propose nomograms for individual risk prediction.Nomograms predict RFS OS were proposed using multi-institutional cohort patients who underwent curative-intent surgery at 13 major institutions in United States...
Abstract Background Surgery for catecholamine-producing tumours can be complicated by intraoperative and postoperative haemodynamic instability. Several perioperative management strategies have emerged but none has been evaluated in randomized trials. To assess this issue, contemporary outcome data from 21 centres were collected. Methods Twenty-one contributed patients who had surgery phaeochromocytoma paraganglioma between 2000 2017. The included the number of with without α-receptor...
Abstract Apoptosis is a physiologic process that serves to eliminate cells during development or in response immunologic regulation. In acute inflammation, however, apoptosis triggered by the overproduction of “death factors” such as TNF-α Fas ligand (FasL) may contribute tissue injury. Both and FasL are presumed convey an apoptotic signal activating cascade cysteine-aspartate proteases, which includes IL-1β-converting enzyme caspase-1. present study, we evaluated contribution FasL, well...
Abstract Vascular endothelial growth factor (VEGF) is the major pro‐angiogenic for most tumors. VEGF expression has been shown to be associated with a poor prognosis in human pancreatic cancer. The purpose of our study was determine effect blockade receptor‐2 activity or without gemcitabine on tumor and metastasis an orthotopic model cancer nude mice. Therapy DC101, antibody, resulted significant reduction primary compared untreated controls. combination DC101 inhibited lymphatic greater...