Xi Chen

ORCID: 0000-0003-0165-6426
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About
Contact & Profiles
Research Areas
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Orthopedic Infections and Treatments
  • Knee injuries and reconstruction techniques
  • Spine and Intervertebral Disc Pathology
  • Cardiac, Anesthesia and Surgical Outcomes
  • Spinal Fractures and Fixation Techniques
  • Hip and Femur Fractures
  • Hip disorders and treatments
  • Acute Myocardial Infarction Research
  • Organ Transplantation Techniques and Outcomes
  • Anesthesia and Pain Management
  • Orthopedic Surgery and Rehabilitation
  • Venous Thromboembolism Diagnosis and Management
  • Bone Tumor Diagnosis and Treatments
  • Sarcoma Diagnosis and Treatment
  • Osteoarthritis Treatment and Mechanisms
  • Acupuncture Treatment Research Studies
  • Shoulder Injury and Treatment
  • Pelvic and Acetabular Injuries
  • Cardiac Ischemia and Reperfusion
  • Artificial Intelligence in Healthcare and Education
  • Medical Research and Treatments
  • Anesthesia and Sedative Agents
  • Oral and Maxillofacial Pathology

West China Hospital of Sichuan University
2022-2025

Sichuan University
2014-2025

Peking Union Medical College Hospital
2013-2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2014-2024

Central South University
2020-2024

Xiangya Hospital Central South University
2024

Hunan Provincial Center for Disease Control and Prevention
2024

Hunan University
2020-2024

Capital Medical University
2020-2024

Beijing Children’s Hospital
2020-2024

Coronary artery disease (CAD) is associated with gut microbiota alterations in different populations. Gut microbe-derived metabolites have been proposed as markers of major adverse cardiac events. However, the relationship between microbiome and stages CAD pathophysiology remains to be established by a systematic study.

10.1186/s40168-019-0683-9 article EN cc-by Microbiome 2019-04-26

The efficacy of large language models (LLMs) in domain-specific medicine, particularly for managing complex diseases such as osteoarthritis (OA), remains largely unexplored.

10.2196/58158 article EN cc-by Journal of Medical Internet Research 2024-06-04

Large Language Models (LLMs) show promise in healthcare tasks but face challenges complex medical scenarios. We developed a Multi-Agent Conversation (MAC) framework for disease diagnosis, inspired by clinical Multi-Disciplinary Team discussions. Using 302 rare cases, we evaluated GPT-3.5, GPT-4, and MAC on knowledge reasoning. outperformed single models both primary follow-up consultations, achieving higher accuracy diagnoses suggested tests. Optimal performance was achieved with four doctor...

10.1038/s41746-025-01550-0 article EN cc-by-nc-nd npj Digital Medicine 2025-03-13

Abstract Aims The instantaneous wave-free ratio (iFR) and whole-cycle Pd/Pa investigate coronary physiology during non-hyperaemic conditions. To test for unique physiologic properties of the period when making resting pressure measurements, we compared post hoc a diastolic (dPR) against iFR numerical similarity test/retest repeatability. Methods results Eight hundred ninety-three lesions from 833 subjects were included VERIFY 2 CONTRAST studies. Diastolic linear transform diagnostic...

10.1093/eurheartj/ehz230 article EN European Heart Journal 2019-04-01

Patient-reported outcome measures (PROMs) are being used increasingly in total knee arthroplasty (TKA). We conducted a systematic review aimed at identifying psychometrically sound PROMs by appraising their measurement properties. Studies concerning the development and/or evaluation of properties TKA population were systematically retrieved via PubMed, Web Science, Embase, and Scopus. Ratings for methodological quality according to updated COnsensus-based Standards selection health...

10.1302/2046-3758.103.bjr-2020-0268.r1 article EN cc-by-nc-nd Bone and Joint Research 2021-03-01

High-grade gliomas (HGG) pose significant challenges in modern tumour therapy due to the distinct biological properties and limitations of blood-brain barrier. This review discusses recent advancements HGG treatment, particularly context immunotherapy cellular therapy. Initially, treatment strategies focus on targeting cells guided by molecular characteristics various gliomas, encompassing chemotherapy, radiotherapy targeted for enhanced precision. Additionally, technological enhancements...

10.3389/fonc.2024.1287725 article EN cc-by Frontiers in Oncology 2024-04-10

Background Accurate preoperative planning is essential for successful total hip arthroplasty (THA). However, the requirements of time, manpower, and complex workflow accurate have limited its application. This study aims to develop a comprehensive artificial intelligent system THA (AIHIP) validate accuracy in clinical performance. Methods Over 1.2 million CT images from 3,000 patients were included an intelligence (AIHIP). Deep learning algorithms developed facilitate automatic image...

10.3389/fmed.2022.841202 article EN cc-by Frontiers in Medicine 2022-03-22

Water availability and nitrogen (N) supply are two major issues that affect plant productivity, however, the processes of water N utilization their hormone regulation not conclusive in response to varying water-N interaction. The objective this study was evaluate effects stress (WS) at different growth stages on maize development, root morphology, utilization, signaling accumulation under various conditions. A set controlled drought 60% field capacity conducted from bell (V12) tassel (VT)...

10.1016/j.agwat.2023.108570 article EN cc-by-nc-nd Agricultural Water Management 2023-10-31

Background The sivelestat is a neutrophil elastase inhibitor thought to have an effect against acute lung injury (ALI) in patients after scheduled cardiac surgery. However, the beneficial of undergoing emergent cardiovascular surgery remains unclear. We aim evaluate on pulmonary protection with ALI Methods Firstly, case-control study 665 from January 1 st , 2020 October 26 th 2022 was performed. 52 who received (0.2mg/kg/h for 3 days) and 613 age- sex-matched controls. Secondly,...

10.3389/fimmu.2023.1082830 article EN cc-by Frontiers in Immunology 2023-01-24

The quality difference of six varieties Ganoderma lucidum with different origins was investigated in this study by comparing the contents ganoderic acid A and B, polysaccharide, triterpenoids. B G. were analyzed ultra performance liquid chromatography (UPLC). There higher content Dabie Mountain Longquan. from Longquan has highest B. polysaccharide determined Anthrone-sulfuric method. is Liaocheng. triterpenoid quantified ultraviolet spectrophotometer at 548.1 nm using Ursolic as standard. In...

10.3389/fphar.2012.00057 article EN cc-by Frontiers in Pharmacology 2012-01-01

Abstract Background and Aim The aim of our study was to investigate the immunomodulatory effect short‐term efficacy long‐term prognosis decompensated liver cirrhosis patients caused by hepatitis B after a double transplantation with human umbilical cord mesenchymal stem cells (hUCMSCs). Methods Fifty inpatients were recruited given same medical treatments, receiving hUCMSCs injection intravenously. Fifty‐three (Group B) matched for age, sex, baseline alanine aminotransferase, aspartate...

10.1111/jgh.14081 article EN Journal of Gastroenterology and Hepatology 2018-01-02
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