A5083064751- Adipokines, Inflammation, and Metabolic Diseases
- Biomarkers in Disease Mechanisms
- Bone Metabolism and Diseases
- Antioxidant Activity and Oxidative Stress
- Viral Infections and Vectors
- Cancer, Lipids, and Metabolism
- Lipoproteins and Cardiovascular Health
- Insect symbiosis and bacterial influences
- Vector-borne infectious diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adipose Tissue and Metabolism
Universiti Teknologi MARA
2017-2024
The role of oxidized high- density lipoprotein (oxHDL) and the protective effects adiponectin in terms vascular calcification is not well-established. This study was conducted to investigate oxHDL with regard inflammation determine attenuating detrimental oxHDL. Cell viability, mineralization, assays were optimize concentration Then, human smooth muscle cells (HAoVSMCs) incubated β-glycerophosphate, HDL, oxHDL, adiponectin, or combination for 24 h. Protein expression IL-6, TNF-α, osterix,...
Low mineralization activity by human osteoblast cells (HOBs) indicates abnormal bone remodeling that potentially leads to osteoporosis. Oxidation, the most prominent form of high-density lipoprotein (HDL) modification, is suggested affect through inflammatory pathway. Adiponectin, which possesses anti-inflammatory activity, postulated have ability suppress detrimental effects oxidized HDL (oxHDL). This study aimed investigate before and after oxidation on markers inflammation. The protective...
Diseases caused by Rickettsiales are often overlooked, although they pose important public health concerns. The family comprises a broad range of intracellular bacteria with distinct evolutionary adaptations, making the development treatment measures to combat infections, such as vaccines or antibiotics, challenge. Interestingly, outer membrane protein A (OmpA) was found exist in cell surface most human pathogenic order Rickettsiales. However, knowledge about OmpA each species and strain is...
Obesity activates inflammation causing dysfunction of adipocytes. Increasing high-density lipoprotein (HDL) levels in obesity may be beneficial overcoming this effect. However, not much data is available on the effects HDL and its subpopulations inflamed The objective study was to investigate total (tHDL) comparison between (HDL2 & HDL3) protein gene expression cholesterol transporters, inflammation, adipokines TNF-α stimulated 3T3-L1 mature TNFα alone had lower adiponectin higher IL-6...