Jie Chen

ORCID: 0000-0002-2470-9159
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About
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Research Areas
  • Polysaccharides and Plant Cell Walls
  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Fungal Biology and Applications
  • PI3K/AKT/mTOR signaling in cancer
  • Enzyme Production and Characterization
  • Aquaculture disease management and microbiota
  • Renal cell carcinoma treatment
  • Immune Response and Inflammation
  • Pharmaceutical Economics and Policy
  • Phytochemical Studies and Bioactivities
  • Psoriasis: Treatment and Pathogenesis
  • Polysaccharides Composition and Applications
  • Dermatology and Skin Diseases
  • Biosimilars and Bioanalytical Methods
  • Ginkgo biloba and Cashew Applications
  • Inflammatory Bowel Disease
  • Antimicrobial Peptides and Activities
  • Biomedical Ethics and Regulation
  • Allergic Rhinitis and Sensitization
  • Biochemical and Structural Characterization
  • Invertebrate Immune Response Mechanisms
  • Tuberous Sclerosis Complex Research
  • Microbial Metabolites in Food Biotechnology
  • Aquaculture Nutrition and Growth

Wenzhou Medical University
2025

Ruian People's Hospital
2025

State Administration of Traditional Chinese Medicine of the People's Republic of China
2022-2024

Shanghai University of Traditional Chinese Medicine
2014-2024

Huazhong Agricultural University
2018

Yueyang Hospital
2014

Union Hospital
2013

Huazhong University of Science and Technology
2013

Renal cell carcinoma (RCC) is a frequent and aggressive type of kidney cancer with limited therapeutic options. Although phosphatase tensin homolog (PTEN) have been recognized as potential tumor suppressor in all kinds cancers, its function RCC remains to be thoroughly elucidated. This article was recruited examine the PTEN's role managing PI3K/AKT pathway impact on proliferation migration. study collected renal adjacent non-cancerous tissue samples from our hospital. HK-2 786-O cells were...

10.1186/s12957-025-03658-9 article EN cc-by-nc-nd World Journal of Surgical Oncology 2025-02-05

The ubiquitin proteasome system (UPS) is a highly regulated mechanism of intracellular protein degradation and turnover. To evaluate the effect crowding stress on UPS in fish, grass carp (Ctenopharyngodon idellus) were randomly reared at low stocking density (LSD, 0.9 kg m-2) or high (HSD, 5.9 for 70 days. expression genes regulating UPS, stress-related parameters, profiles amino acid white muscle as well growth rate fish two densities investigated. Fish exhibited significantly higher LSD...

10.3389/fphys.2018.00837 article EN cc-by Frontiers in Physiology 2018-07-05

Although Traditional Chinese medicine (TCM) is known to be effective for psoriasis patients, the responsible mechanisms still remain poorly understood. In this study, we aimed evaluate effect of one formula, named Jueyin granules (JYG) in mouse model vaginal epithelium and tail epidermis. Additionally, also determined anti-inflammatory effects JYG an imiquimod- (IMQ-) induced psoriasis-like skin model. Our results show that can attenuate IMQ-induced inflammation, accompanied with increased...

10.1155/2014/512562 article EN cc-by Evidence-based Complementary and Alternative Medicine 2014-01-01
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