A5091147333- Ethnobotanical and Medicinal Plants Studies
- Malaria Research and Control
- Diverse Scientific Research Studies
- Drug-Induced Hepatotoxicity and Protection
- Antibiotic Use and Resistance
- Pharmacological Effects of Natural Compounds
- Natural Antidiabetic Agents Studies
- Traditional and Medicinal Uses of Annonaceae
- Pneumonia and Respiratory Infections
- Pharmaceutical Practices and Patient Outcomes
- Atrial Fibrillation Management and Outcomes
- Insect Pest Control Strategies
- Complementary and Alternative Medicine Studies
- Advances in Cucurbitaceae Research
- Phytochemical and Pharmacological Studies
- Phytochemistry and Biological Activities
- Epilepsy research and treatment
- Cardiac Arrhythmias and Treatments
- Venous Thromboembolism Diagnosis and Management
- Neonatal and fetal brain pathology
- Pharmacological Effects and Toxicity Studies
- Herbal Medicine Research Studies
- Moringa oleifera research and applications
- Computational Drug Discovery Methods
- Natural product bioactivities and synthesis
University of Gondar
2016-2025
Pain and inflammation are the major devastating health problems commonly treated with traditional medicinal plants in Ethiopia. Echinops kebericho M. (Asteraceae) is one which frequently used to treat pain by healers Ethiopian folk medicine. However, plant has not been scientifically evaluated for its traditionally claimed use. The present study aimed at investigation of analgesic anti-inflammatory activities 80% methanol root extract mice model.Successive maceration was as a method...
Background Although diarrhea is a preventable disease, it continues to have significant impact on global health, with the burden being much greater in Sub-Saharan Africa. Medicinal plants represent affordable and locally available resources address many diseases, including diarrhea. Thus, this study aimed investigate antidiarrheal activities of 80% hydromethanolic crude extract solvent fractions Terminalia brownii Fresen (Combretaceae) leaves Swiss Albino mice. Methods This was carried out...
In addition to pharmacovigilance and pharmaco-economic concerns, resistance anti-malarial medicines has been documented in all classes of anti-malarials this is further worsened by common insecticides malaria vector, which a major threat control. As means facing the challenges searching for new agents, current study focused on evaluation activity root extract Indigofera spicata.Chloroquine-sensitive rodent parasite, Plasmodium berghei (ANKA strain) was used infect Swiss Albino mice 4-day...
Objective: The aim of this study was to assess the practice pharmacotherapy epilepsy and its treatment outcomes in adult epileptic outpatients at University Gondar Referral Teaching Hospital, Gondar, North West Ethiopia. Methods: An institution based, retrospective cross-sectional conducted from medical charts 336 patients outpatient clinic Neurology Department Hospital May 2014 April 2015. Reviewing follow-up information used evaluate antiepileptic drug (AED) prescribing patterns outcome....
Background: Self-medication practice is the use of medications without healthcare professional requests. It can lead to inappropriate medication usage, wastage resources, increased chance microbial resistance, and adverse drug reactions. Therefore, this study aimed at assessing prevalence associated factors self-medication among teachers’ education training college students in Amhara region, Ethiopia. Methods: A multicentre cross-sectional was conducted on 344 Ethiopia, from January 1...
The use of traditional medicinal plants in the management diarrhea has long been practiced Ethiopia. B. abyssinica fresen is one traditionally used to treat whereas an vivo study had not yet conducted. Thus, this aimed evaluate antidiarrheal activity crude extract and solvent fractions leaf mice.Cold maceration within 80% methanol was powder fractionated using n-hexane, chloroform, distilled water. extracts were tested experimental models castor oil-induced diarrhea, enteropooling,...
Background. The management and control of malaria has become gradually challenging due to the spread drug-resistant parasites, lack effective vaccine, resistance vector insecticides. Consequently, novel agents are urgently needed from different sources including medicinal plants. In Ethiopia Uganda, Myrica salicifolia root is traditionally claimed for treatment malaria. aim this study was evaluate in vivo antimalarial activity crude extract M salicifolia. Methods. parasite, Plasmodium...
Background. Malaria is a major public health problem in developing countries. In Ethiopian, the seeds of Schinus molle are used for management malaria. Therefore, current study aimed to evaluate vivo antimalarial activity hydro-alcoholic crude extract and solvent fractions Plasmodium berghei infected mice. Methods. An 80 percent methanolic were tested at 100, 200 400 mg/kg doses. The parasitemia level, packed cell volume, body weight, survival date rectal temperature anti-malarial extracts....
To evaluate the diuretic effects of aqueous (AQ) and hydromethanolic crude extract (HM) as well solvent fractions HM from Erica arborea flowers in mice.
Background. Current malaria treatment is associated with continued development of drug resistance. Thus, there a need to develop safe and effective new treatments from different sources. Solanum nigrum L. (Solanaceae) plant used for the in Ethiopian traditional medicine. This study was aimed at evaluating antimalarial activity crude extract fractions S. leaves against P. berghei infection mice. Method. Both prophylactic suppressive models were using ANKA Plasmodium strain. In these models,...
Despite the well-established effectiveness of anticoagulants, risk their hemorrhagic complications withheld many patients from being maintained on anticoagulant therapy. However, there is no sufficient data magnitude and factors associated with anticoagulant-related in resource-constrained settings. Thus this study aimed to assess related therapy among at University Of Gondar Comprehensive Specialized Hospital. A retrospective follow-up was done 154 individuals starting June 2018 2019 adult...
Introduction: Most parts of the plant Clutia abyssinica is traditionally used in different diseases because their medicinal properties. The roots are widely traditionally, as diuretic purpose, liver problems, enlarged spleen and kidney problems. present study was carried out to evaluate effect methanolic extracts rats comparison with standard drug furosemide. Methodology: Thirty either sex were randomly allocated into five groups six each. pretreated physiological saline (0.9% NaCl, po) at...
Malaria continues to be a global public health threat. In Africa, malaria accounts for substantial morbidity and mortality. The emergence of drug resistant parasites subsequent decrement in effectiveness current antimalarial medications have complicated control. This urged developing an effective alternative agent. Leaves root Stephania abyssinica (Dill. & A. Rich.) Walp. is traditionally used the treatment east African countries such as Ethiopia proved its vitro efficacy. Hence, this...
Abstract Background Self-medication practice is the use of medications without health care professional request. It leads to irrational medication usage, wastage resources, increased chance microbial resistance and adverse drug reaction. Therefore, this study aimed at assessing prevalence associated factors self-medication among students teacher’s education training college in Amhara region, Ethiopia. Methods A multicentre cross-sectional was conducted on 344 teacher's from January 1...
Abstract Background: Due to drug resistance and inefficient eradication techniques, malaria continues be a major public health issue in countries with low- middle-income. The seeds of Schinus molle are used the Ethiopian folklore medicine for treatment malaria. However, this claim is not yet supported scientific researches. Hence, current study aims investigate vivo, antimalarial activity hydro-alcoholic crude extract subsequent solvent fraction on Plasmodium berghe infected mice. Methods: A...