A5012153028- Lung Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Tissue Engineering and Regenerative Medicine
- Pleural and Pulmonary Diseases
- Tracheal and airway disorders
- Pulmonary Hypertension Research and Treatments
- Advanced Radiotherapy Techniques
- Lung Cancer Treatments and Mutations
- Sarcoidosis and Beryllium Toxicity Research
- Cancer therapeutics and mechanisms
- Hepatocellular Carcinoma Treatment and Prognosis
- Vascular Anomalies and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Congenital Heart Disease Studies
- Occupational and environmental lung diseases
- Mechanical Circulatory Support Devices
- Radiopharmaceutical Chemistry and Applications
- Lung Cancer Research Studies
- Pneumonia and Respiratory Infections
- Sexual function and dysfunction studies
- Cardiac tumors and thrombi
- Salivary Gland Tumors Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Respiratory Support and Mechanisms
- Breast Cancer Treatment Studies
Helios Universitätsklinikum Wuppertal
2016-2024
Medizinische Hochschule Hannover
2004-2019
Helios Dr. Horst Schmidt Kliniken Wiesbaden
2012
Lungenklinik Hemer
2007
University Medical Center Freiburg
2007
Hannover Re (Germany)
2005
The emergence of multi-drug resistant bacteria threatens to end the era antibiotics. Drug have evolved mechanisms overcome antibiotics at therapeutic doses and further dose increases are not possible due systemic toxicity. Here we present a pilot study ex vivo lung perfusion (EVLP) with high antibiotic therapy followed by autotransplantation as new last resort for otherwise incurable multidrug infections. Severe Pseudomonas aeruginosa pneumonia was induced in lower left lungs (LLL) 18...
Due to therapeutic implications with regard both efficiency and safety of chemotherapy agents it is important differentiate between subtypes NSCLC. Up today we experience a continuous reservation regarding the use fine needle aspiration cytology. The aim present study estimate value cytologic criteria for lung cancer typing on small biopsies independent from all possible technique failures. Between January 1997 December 2008 760 intraoperative FNAC- (fine cytology) specimens 702 patients...
Abstract OBJECTIVES Solitary fibrous tumours of the pleura (SFTP) are historically considered to be benign soft tissue neoplasms. However, a clinical relevant number these neoplasms have malignant histological features. The objective this study was evaluate percentage SFTP presenting unfavourable behaviour in order predict negative long-term outcome. METHODS A retrospective review 74 patients treated at 4 hospitals between 1990 and 2013 performed. median follow-up 10 years (range: 1–20...
In many cases unresectable or recurrent pulmonary metastases do not respond to systemic chemotherapy the side-effects are acceptable. Based on results of our experiments isolated lung perfusion could improve option local chemotherapy. Parameters for edema formation (relative increase in weight, gas exchange, histopathology) were evaluated during extracorporal ventilation and reperfusion lobes resected cancer. Drug concentration was measured tissue, tumour hilar lymphnodes. Irinotecan...
<b>Background: </b>History, clinical presentation, lung function testing, radiographs including HRCT and nonsurgical biopsy techniques in most cases provide sufficient information for classification of interstitial disease (ILD). However, a small percentage it is not possible to establish the diagnosis so that may be required. We analyzed under which circumstances reduction invasive procedures reasonable. <b>Methods:</b> Between January 1997 December 2009 we examined 3399 specimens from 1299...
Lung auto-transplantation is the surgical key step in experiments involving ex vivo therapy of severe or end-stage lung diseases. Ex has become a clinical reality because systems such as Organ Care System (OCS) Lung, which only commercially available portable perfusion system. However, survival porcine pose special and anaesthesiological challenges. This current study was designed to describe development techniques aneasthesiological management strategies that facilitate surgery including...
Objectives: Optimal visualisation of distal branches during pulmonary endarterectomy (PEA) is essential for complete removal organised thrombo-embolic material. Herewith, we describe a modification the standard approach that improves surgical exposure PEA procedure. Methods: From January 2013 to March 2014, 25 patients with chronic hypertension (CTEPH) (NYHA class III and IV) underwent at Hannover Medical School using our modified technique (dislocation group). We compared this group...