A5082602778- Berberine and alkaloids research
- Phytochemicals and Antioxidant Activities
- Phytochemical Studies and Bioactivities
- Natural product bioactivities and synthesis
- Essential Oils and Antimicrobial Activity
- Phytoestrogen effects and research
- Natural Antidiabetic Agents Studies
- Plant-based Medicinal Research
- Ethnobotanical and Medicinal Plants Studies
- Phytochemistry and Biological Activities
- Potato Plant Research
- Food Quality and Safety Studies
- Biological and pharmacological studies of plants
- Seed and Plant Biochemistry
- Pharmacology and Obesity Treatment
- Medicinal Plants and Neuroprotection
- Pharmacological Effects of Natural Compounds
- Synthesis and Characterization of Heterocyclic Compounds
- Analytical Methods in Pharmaceuticals
- Animal Nutrition and Physiology
- African Botany and Ecology Studies
- Gout, Hyperuricemia, Uric Acid
- Complementary and Alternative Medicine Studies
- Food Science and Nutritional Studies
- Traditional and Medicinal Uses of Annonaceae
National Botanical Research Institute
2019-2025
This work deals with the development of a greener RP-HPLC method and chemical pattern recognition for identification Acorus calamus L. collected from different natural sources samples traded as ‘ Vacha ’ in Indian herbal drug markets.
Malnutrition and hunger is a serious global issue, however, wild fruits possess the potential of combatting it being rich in nutrients.
The genus Berberis has high significance in Indian and other traditional systems of medicine due to the presence iso-quinoline alkaloids. This study was conducted record metabolic variation eight spp. collected from Western Himalayan region. RP-HPLC-PDA chromatogram separates markers jatrorrhizine, palmatine berberine at specific retention time, 11.45, 16.41 18.15 min respectively. method validated on linearity, precision recovery indices as per International Conference Harmonisation (ICH)...
Abstract Gloriosine, the predominant metabolite of Gloriosa superba L., shares chemical properties with colchicine. We analyze microtubule-binding affinity gloriosine at colchicine binding site (CBS) using an in silico-in vivo approach. The In silico docking showed a score (−) 7.5 kcal/Mol towards β-tubulin CBS and was validated by overlapping coupling pose docked ligand co-crystallized 2D plots (Ligplot +) > 85% overlap between ADMET profile accordance Lipinski’s rule five. Gloriosine...
The present study has been planned to evaluate the impact of seasonal variation in labdane-type diterpenoids namely isoforskolin, forskolin, 1,9-dideoxyforskolin and 1-deoxyforskolin Coleus forskholii (roots). plant samples were harvested different seasons from our experimental field located at CSIR-NBRI garden, Lucknow (India) metabolite contents estimated through validated high performance thin layer chromatography (HPTLC) method. HPTLC plate was developed tertiary mobile phase...
Coscinium fenestratum (Goetgh.) Colebr. is widely used for urinary disorders and kidney stones by ethnic communities in southern India. The species documented various ancient Indian Ayurvedic literatures having therapeutic use 'Ashmari' i.e., urolithiasis. present study aims at validation of in-vitro anti-urolithiatic potential extracts C. stem along with identification quantification major bioactive alkaloids, berberine palmatine through HPTLC LC-MS/MS. Water extract showed maximum activity...
Gloriosa superba is a valuable Ayurvedic medicinal plant and in high demand the world market for its colchicine content, which used to treat gout.The study aims (1) record metabolic variations major bioactive metabolites, gloriosine, natural populations of G. from Western Ghats adjoining areas India (2) develop HPTLC protocol identification elite chemotypes species regulation quality raw material, extract, finished material.Simultaneous quantification gloriosine 22 through validated as per...
The metabolic variation of berberine and palmatine content in the roots Berberis lycium was analyzed by HPTLC–UV for identification quality raw material (QRM) used industry. Ten natural population(s) were mapped, samples collected from different parts Western Himalayas. Pharmacognostical parameters each evaluated as per Ayurvedic pharmacopoeia India (API) quality. HPTLC chromatogram developed n-propanol-water-formic acid (9:1:0.1 v/v/v) quantified at λmax 350 nm. Rf 0.2 ± 0.08 0.33 0.03,...
Background Costus speciosus (J. Koenig) Sm. (Syn. Cheilocostus speciosus) is an ethnic anti-diabetic plant, used for its high diosgenin content. Objectives This study aimed to evaluate the seasonal variation of content in rhizome, quantified through validated RP-HPLC method. Materials and Methods The rhizomes were collected four different seasons, such as rainy (August), autumn (October), winter (February) summer (May), from Lucknow, India. HPLC method validation was done terms linearity,...