Manish Kumar

ORCID: 0000-0003-2042-1243
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About
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Research Areas
  • Advanced Drug Delivery Systems
  • Advancements in Transdermal Drug Delivery
  • Drug Solubulity and Delivery Systems
  • Nanoparticle-Based Drug Delivery
  • Essential Oils and Antimicrobial Activity
  • Analytical Methods in Pharmaceuticals
  • Computational Drug Discovery Methods
  • RNA Interference and Gene Delivery
  • Curcumin's Biomedical Applications
  • Natural Antidiabetic Agents Studies
  • Pharmacological Effects of Natural Compounds
  • Graphene and Nanomaterials Applications
  • Drug-Induced Hepatotoxicity and Protection
  • Lipid Membrane Structure and Behavior
  • Natural product bioactivities and synthesis
  • Ocular Surface and Contact Lens
  • Ethnobotanical and Medicinal Plants Studies
  • Nanoplatforms for cancer theranostics
  • Nanoparticles: synthesis and applications
  • Research on Leishmaniasis Studies
  • Phytochemistry and Biological Activities
  • Synthesis and biological activity
  • Antibiotics Pharmacokinetics and Efficacy
  • Phytochemicals and Antioxidant Activities
  • Polysaccharides Composition and Applications

Indo Soviet Friendship College of Pharmacy
2024-2025

NIMS University
2025

Central University of Haryana
2025

Banaras Hindu University
2008-2024

National Institute of Malaria Research
2024

Maharishi Markandeshwar University, Mullana
2017-2024

Indian Institute of Technology Indore
2014-2024

Jaipur National University
2024

Indian Institute of Technology Bhilai
2023-2024

King George's Medical University
2024

ABSTRACT The clinical value of amphotericin B, the mainstay therapy for visceral leishmaniasis in sodium antimony gluconate-nonresponsive zones Bihar, India, is now threatened by emergence acquired drug resistance, and a comprehensive understanding underlying mechanisms need hour. We have selected an B-resistant isolate which demonstrated 8-fold-higher 50% lethal doses (LD 50 ) than B-sensitive strain to explore mechanism B resistance. Fluorimetric analysis lower anisotropy motion...

10.1128/aac.00030-11 article EN Antimicrobial Agents and Chemotherapy 2011-11-30

Nanotechnology is indisputably a scientific technique that offers the prospect of new therapies, and hope, for treatment malignant illnesses. It novel technology approaches diagnosis management diverse diseases. Although discovery Quantum dots (QD) nano-transporters has already led to few positive developments, QD are still at their initial stage, though have yet proven valuable society. The excertion indicates conversion in natural imaging along with photograph established incredible...

10.3389/fmats.2021.798440 article EN cc-by Frontiers in Materials 2022-01-10

Silver nanoparticles induced alterations in multiple cellular targets, which are critical for drug susceptibilities and pathogenicity fungal pathogen (Candida albicans) Venkatraman Srinivasan Radhakrishnan,1,2 Mohana Krishna Reddy Mudiam,3 Manish Kumar,1,2 Surya Prakash Dwivedi,4 Surinder Pal Singh,5 Tulika Prasad1,2 1Advanced Instrumentation Research Facility (AIRF), Jawaharlal Nehru University (JNU), New Delhi, India; 2Special Centre Nano Sciences (SCNS), 3Analytical Chemistry Lab, Council...

10.2147/ijn.s150648 article EN cc-by-nc International Journal of Nanomedicine 2018-05-01

Journal Article Sensitivity of food pathogens to garlic (Allium sativum) Get access M. Kumar, Kumar Department Animal Products Technology, CCS Haryana Agricultural University, Hisar, India Search for other works by this author on: Oxford Academic Google Scholar J.S. Berwal Hisar‐125001, India. Applied Microbiology, Volume 84, Issue 2, 1 February 1998, Pages 213–215, https://doi.org/10.1046/j.1365-2672.1998.00327.x Published: 01 1998 history Received: 06 January 1997 Revision received: 30...

10.1046/j.1365-2672.1998.00327.x article EN Journal of Applied Microbiology 1998-02-01

High gold affinity impurities (halides, bases) in solvents, starting materials, filtration, or drying agents could affect the reactivity of catalyst adversely, which may significantly reduce TON cationic gold-catalyzed reactions. Use a suitable acid activator (e.g., HOTf, In(OTf)3) reactivates and makes reaction proceed smoothly at low loading.

10.1021/ol501663f article EN publisher-specific-oa Organic Letters 2014-06-17

Objective: The present work evaluated whether the prepared nanoparticles (NPs) would be able to target drug brain by a non-invasive nasal route enhancing its bioavailability.

10.1517/17425247.2014.894504 article EN Expert Opinion on Drug Delivery 2014-03-22

The 4-allyl guaiacol is a natural phenolic molecule that has been widely studied for its antioxidant capacity against reactive-oxygen-species-mediated cellular damage. Therefore, we hypothesized concomitant use of an and NSAID may decrease the risk gastrointestinal toxicity make therapy safer. To address conventional NSAIDs, new S-naproxen-4-allyl chimera (MAS-1696) was computationally developed, chemically synthesized, tested anti-inflammatory effectiveness safety. inhibitory potency...

10.3390/molecules27206905 article EN cc-by Molecules 2022-10-14

Alzheimer's disease (AD) is a neurodegenerative that affects wide range of populations and the primary cause death in various countries. The treatment AD still restricted to oral conventional medicines act only superficially. Fabrication intranasal solid lipid nanoparticulate system for uptake therapeutic agents will as convincing approach with limited off-site toxicity increased pharmacological activity. objective this study was formulate, optimize, evaluate efficiency rivastigmine tartrate...

10.3389/fnagi.2022.960246 article EN cc-by Frontiers in Aging Neuroscience 2022-08-11

In the past, curcumin was go-to medication for diabetes, but recent studies have shown that tetrahydrocurcumin is more effective. The problem it's not very soluble in water or bioavailable. So, our research aims to increase bioavailability and anti-diabetic efficacy of streptozotocin-induced diabetic rats by synthesizing tetrahydrocurcumin-loaded solid lipid nanoparticles. Box Behnken Design employed optimization nanoparticles (THC-SLNs). optimal formulation determined doing an ANOVA examine...

10.1016/j.jsps.2023.101727 article EN cc-by-nc-nd Saudi Pharmaceutical Journal 2023-08-02
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