A5071889869- Advanced Drug Delivery Systems
- Graphene and Nanomaterials Applications
- Chemical Synthesis and Analysis
- Drug Solubulity and Delivery Systems
- Nanoparticle-Based Drug Delivery
- Computational Drug Discovery Methods
- Advancements in Transdermal Drug Delivery
- Protein Hydrolysis and Bioactive Peptides
- Pharmacological Effects of Natural Compounds
- Antimicrobial Peptides and Activities
- Biological Research and Disease Studies
- Analytical Methods in Pharmaceuticals
- Phytochemistry and biological activities of Ficus species
- Carbon and Quantum Dots Applications
- Biochemical and Structural Characterization
- COVID-19 Digital Contact Tracing
- Click Chemistry and Applications
- RNA Interference and Gene Delivery
- Crystallization and Solubility Studies
- Kidney Stones and Urolithiasis Treatments
- Peptidase Inhibition and Analysis
- Long-Term Effects of COVID-19
- Multicomponent Synthesis of Heterocycles
- Carbon Nanotubes in Composites
- ATP Synthase and ATPases Research
Maharishi Markandeshwar University, Mullana
2020-2025
Banasthali University
2023-2024
Background: In recent years, transdermal drug delivery systems (TDDS) have gained popularity as a non-invasive, patient-friendly medication method. Objective: This review article examines the latest developments and breakthroughs. The begins with brief summary of administration, stressing skin's barrier role permeation methods. Novel materials methods improve solubility, stability, skin permeability in formulation technologies. Methods: A literature most innovations TDDS, such nano-based...
The lipid-based drug delivery system (LBDDS) is a well-established technique that anticipated to bring about comprehensive transformations in the pharmaceutical field, impacting management and administration of drugs, as well treatment diagnosis. Various LBDDSs verified be an efficacious mechanism for monitoring hypertension systems are SEDDS (self-nano emulsifying delivery), nanoemulsion, microemulsions, vesicular (transferosomes liposomes), solid lipid nanoparticles. overcome shortcomings...
In this manuscript we report the development of multiwalled carbon nanotubes-docetaxel conjugate by covalent interaction, involving nucleophilic substitution reaction mechanism. The surface functionalization nanotubes was carried out enrichment carboxylic groups with optimized oxidation treatment. carboxyl were converted to acyl followed attachment docetaxel a cleavable ester linkage. drug nanotube characterized Fourier Transform Infra red, UV-Visible, Raman spectroscopy, Scanning and...
Integerrimide-A (IG-A) is a cyclic heptapeptide that was recently synthesized after being recovered from the latex of Jatropha integerrima tree. This achieved by first coupling tetrapeptide unit (Boc-Gly-L-Leu-L-Leu-L-Leu-OMe) with tripeptide (L-Thr-L-Pro-L-Trp-OMe). The characterization done using spectral techniques like FT-IR, 1H-NMR, mass spectrometry, and elemental analysis newly molecule. Antimicrobial anticancer properties IG-A were tested biological screening. Gram +ve bacteria (B....
Fast dispersible tablets (FDTs) get dispersed very fast due to which the discrimination of in vitro drug release and their evaluation is difficult. Hence present study a new discriminatory dissolution method was developed validated for FDTs domperidone BCS class II.FDTs were prepared by direct compression method. The studies performed an eight-station Electrolab TDT-082 testing apparatus, analyzed ultraviolet spectrophotometer evaluated different mediums i.e. sodium lauryl sulphate (0.5%,...
Background: Cancer is a leading cause of death for people worldwide, in addition to the rise mortality rates attributed Covid epidemic. This allows scientists do additional research. Here, we have selected Integerrimide A, cordy heptapeptide, and Oligotetrapeptide as three cyclic proteins that will be further studied investigated this context. Methods: Docking research was carried out using protein complexes 1FKB 1YET, downloaded from PDB database used docking investigations. Cyclopeptides...
Abstract: Considering that cancer is a disease affects people all over the world, there has been movement in focus of scientific and research efforts towards substances are acquired from natural sources. This shift occurred as result fact people. It demonstrated identification pharmaceuticals originating plants proven to be particularly beneficial process producing anticancer therapies such vincristine, vinblastine, paclitaxel, irinotecan. Additionally, marine sources have provided...
Abstract: GA (Gallic acid) belongs to the phenolic molecule that is naturally present in plants, and has an assortment of medicinal benefits on inflammation, obesity, cancer, heart, neurological system, proliferation cells. In more recent research, anti-cancer effects via biological mechanisms such as angiogenesis, migration, metastasis, cell cycle arrest, apoptosis have been demonstrated. Anti-cancer activities gallic acid are affected through methods which involve reluctance tumor etc....
The synthesis of biologically active molecules carried out by using Aminothiazole nuclei and their various derivatives as precursors. In present work, Schiff's bases (27-36) were prepared reacting amino group thiazole moiety (26) with aromatic aldehydes. titled, novel 2-substituted aminothiazoles (37-46) obtained reaction these benzil providing excess amount ammonium acetate (NH4OAc). Structure elucidation all the newly synthesized compounds was employing elemental analysis, FT-IR, 1H NMR...
Abstract Plant derived compounds are drawing attention in curing and treating variety of ailment diseases. This increase popularity natural products has renewed interest garlic, which been used by human for centuries. It found that garlic pulp contains more than 200 chemical numerous molecules can still be explored, extracted, synthesized optimized. As market various preparations available include tablets made from dried powdered clove, oils liquid extracts however, it would also interesting...
The incidence of nephrolithiasis, commonly known as kidney stone, is increasing worldwide with significant health and economic burden. Approximately 2 million people every year in India are affected by stones. It affects all ages, genders, races, but between the ages 20 49 years, it most frequently men than women. Different types stones include calcium stones, cysteine struvite or magnesium ammonium phosphate uric acid drug-induced This review article provides information about general...
The nature and magnitude of genetic parameters like components variance (additive, dominance epistatic), coefficient variation, heritability advance may vary from character to for the same population, population environment character. An abiotic stress be major cause such variations. variation relatively much more if there is simultaneous occurrence two or stresses as drought, salt heat coupled with high seasonal interannual variability environment. High temperature affects wheat crop yield...