A5082281202- Computational Drug Discovery Methods
- Synthesis and biological activity
- Advanced Drug Delivery Systems
- Synthesis and Biological Evaluation
- Natural Antidiabetic Agents Studies
- Cholinesterase and Neurodegenerative Diseases
- Multicomponent Synthesis of Heterocycles
- Essential Oils and Antimicrobial Activity
- Advancements in Transdermal Drug Delivery
- Ethnobotanical and Medicinal Plants Studies
- Phytochemicals and Antioxidant Activities
- Synthesis and Characterization of Heterocyclic Compounds
- Drug Solubulity and Delivery Systems
- Curcumin's Biomedical Applications
- Research on Leishmaniasis Studies
- Free Radicals and Antioxidants
- Eicosanoids and Hypertension Pharmacology
- Click Chemistry and Applications
- Receptor Mechanisms and Signaling
- Nanoparticle-Based Drug Delivery
- Dermatology and Skin Diseases
- Advances in Cucurbitaceae Research
- Alzheimer's disease research and treatments
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
Banasthali University
2016-2025
Lala Lajpat Rai Memorial Medical College
2014-2024
Dr. D. Y. Patil Medical College, Hospital and Research Centre
2021
Graphic Era University
2020
Alembic Pharmaceuticals (India)
2019
Jamia Hamdard
2016
Oil and Natural Gas Corporation (India)
2006
University of California, Santa Barbara
2005
Rani Durgavati University
1997-1998
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMolecular Torsion Balance for Weak Molecular Recognition Forces. Effects of "Tilted-T" Edge-to-Face Aromatic Interactions on Conformational Selection and Solid-State StructureS. Paliwal, S. Geib, C. WilcoxCite this: J. Am. Chem. Soc. 1994, 116, 10, 4497–4498Publication Date (Print):May 1, 1994Publication History Published online1 May 2002Published inissue 1...
Ethosomes have been widely used in Transdermal Drug Delivery System (TDDS) as they increase the permeation of drug across skin.Flurbiprofen loaded vesicular ethosomes were formulated, optimized and characterized for particle size, entrapment efficiency, poly dispersive index (PDI), microscopy using Atomic force (AFM), Scanning electron microscope (SEM) Transmission (TEM) Interaction excipients studied Fourier transform infra-red (FTIR) spectroscopy, Differential scanning colorimetry (DSC),...
The chemistry of 1,3,4-thiadiazole is one the most interesting scaffolds for synthesizing new drug molecules due to their numerous pharmacological activities. Several modifications in thiadiazole ring have been made, proving it be more potent and highly effective with a less toxic scaffold various biological There are several marketed drugs containing structure. In this review article, we tried compile newly synthesized derivatives possessing important pharmaceutical significance since 2014.
Corneal diseases are a major cause of vision loss worldwide. Traditional methods like corneal transplants from donors effective but face challenges limited donor availability and the risk graft rejection. Therefore, new treatment essential. This review examines growing field bioprinting biofabrication in tissue engineering. We begin by discussing various such as stereolithography, inkjet, extrusion printing, highlighting their strengths weaknesses for eye-related uses. also explore how...
Abstract Pyrazole is a versatile lead compound to design potent bioactive molecules for drug discovery and development, particularly in cancer therapy. The aim of this review present the most recent deeds field synthetic route made functionalized pyrazole derivatives active against cell proliferation disease. article covers synthesis 1H-pyrazole, N-substituted pyrazoles, pyrazolopyrazoles, pyrazoles fused with naturally occurring moiety. Some these reported compounds have passed preclinical...
Abstract Alzheimer’s disease (AD) is a multifaceted neurodegenerative condition. The pathogenesis of AD highly intricate and the apparent in aged population ~ 50–70 years old. Even after > 100 research, root origin its unclear, complex multifaceted. Herein, we have designed synthesized 9 novel molecules with three different heterocyclic scaffolds namely pyrrolidone-2-one, quinoline & indoline-2-one to imitate explore chemical space around donepezil. were evaluated for their potential...
Persistent Organic Pollutants (POPs) enter into the environment through various anthropogenic activities and cause air, water soil pollution depending on their persistence in different matrices. POPs present all segments of are inherently toxic accumulate food products by atmospheric deposition from translocation plants contaminated soils seafood polluted water. Moreover, also get with during cooking processes including grilling roasting. settle down surface fallout air. The degradation...
The aim of the current investigation is to evaluate transdermal potential novel vesicular carrier, ethosomes, bearing aceclofenac, Non-steroidal anti-inflammatory drugs (NSAIDs) agents having limited permeation. Aceclofenac loaded ethosomal carriers were prepared, optimized and characterized for shape surface morphology,(SEM) scanning electronic microscopy, size, entrapment efficiency, stability, in- vitro release study. formulation (Etho5) 3% phospholipids contant 40% ethanol showing grater...
Abstract In the present investigation, proniosomes of risperidone were formulated, optimized and evaluated for effective transdermal delivery in order to overcome bioavailability issues orally administered risperidone. The prepared using various sorbitan esters with cholesterol soya lecithin in-vitro parameters, ex-vivo permeation in-vivo performance. Results indicated that vesicles spherical shape, their size ranged from 284.00 nm 941.40 nm they had high zeta potential. entrapment...
Background: Angelica glauca (AG) (family Apiaceae) is used by tribes as a spice and to treat various diseases. Before consumption, effective measures must be for quality control tests. This study establishes standards A. glauca. The analyses roots physico-chemical, pharmacognostic, phytochemical, heavy metals, pesticidal residue, microbial load, aflatoxin Methods: standard procedure was powder microscopy physiochemical parameters. Multiple culture media were measure load. Aflatoxins...
Abstract: Epilepsy is the second most typical chronic disorder, described by recurrent seizures and uncontrolled electrical signaling from neurons in cerebral cortex. Stimulated astrocytes, along with microglia, promote cytokines that cause neuroinflammation, leading to a chain reaction of subsequent steps involving as well endothelial cells blood-brain barrier. Inflammation brain’s neural network can convulsions epilepsy. The migration albumin proteins infiltration peripheral immune serum...