A5041943773- Musculoskeletal pain and rehabilitation
- Acupuncture Treatment Research Studies
- Computational Drug Discovery Methods
- Spine and Intervertebral Disc Pathology
- Synthesis and biological activity
- Crystallization and Solubility Studies
- Peroxisome Proliferator-Activated Receptors
- X-ray Diffraction in Crystallography
- Eicosanoids and Hypertension Pharmacology
- Crystallography and molecular interactions
- Medical Imaging and Analysis
- Crystal structures of chemical compounds
- Synthesis and Biological Evaluation
- Research on Leishmaniasis Studies
- Synthesis and Characterization of Heterocyclic Compounds
- Nanoparticle-Based Drug Delivery
- Advanced Drug Delivery Systems
- Antibiotics Pharmacokinetics and Efficacy
- Metal complexes synthesis and properties
- Graphene and Nanomaterials Applications
- Pharmacological Effects of Natural Compounds
- Cholinesterase and Neurodegenerative Diseases
- Birth, Development, and Health
- Rice Cultivation and Yield Improvement
- Toxin Mechanisms and Immunotoxins
King Khalid University
2020-2025
Queen Mary University of London
2024-2025
Hajee Mohammad Danesh Science and Technology University
2024
Bangladesh Agricultural University
2022-2024
Bangladesh Council of Scientific and Industrial Research
2023-2024
Birla Institute of Technology, Mesra
2012-2023
University of Chittagong
2013-2023
Bangladesh Livestock Research Institute
2023
Krea University
2022
University of Science and Technology Chittagong
2022
Abstract Protein oxidation sits at the intersection of multiple signalling pathways, yet magnitude and extent crosstalk between other post-translational modifications remains unclear. Here, we delineate global changes in adipocyte networks following acute oxidative stress reveal considerable cysteine phosphorylation-based signalling. Oxidation key regulatory kinases, including Akt, mTOR AMPK influences fidelity rather than their absolute activation state, highlighting an unappreciated...
Breast cancer is a challenging health issue in women and the second-leading cause of mortality around world. In this review, we addressed beneficial role siRNA to control breast cancer. Various limitations based therapeutic approaches, innate challenges delivery, vitro vivo findings have been highlighted focus recent advancement The current approaches comparative assessment against conventional chemotherapeutics methods thoroughly investigated for conclusive outcomes. nanocomposites...
An effective and sensitive analytical method was developed to quantify the most common pesticide residues (difenoconazole, dimethoate, pymetrozine, chlorantraniliprole) used for brinjal cultivation in Bangladesh. The quantification of analytes done using liquid chromatography-tandem mass spectrometry (LC-MS/MS). samples were extracted a modified QuEChERS followed by purification with dispersive solid phase extraction (d-SPE) sorbents (PSA, GCB, C18). Matrix-matched calibration regression...
Neurodegeneration is a term describing an irreversible process of neuronal damage. In recent decades, research efforts have been directed towards deepening our knowledge numerous neurodegenerative disorders, with particular focus on conditions such as Alzheimer's disease (AD). Human transferrin (htf) key player in maintaining iron homeostasis within brain cells. Any disturbance this equilibrium gives rise to the emergence diseases and associated pathologies, particularly AD. Limonene,...
This work aimed to investigate the effect of edible coatings on shelf life and quality tomato fruits. Aloe vera (AL) gel tulsi leaf extract (TE), a combination aloe (ALTE) coating, were applied surface fresh tomatoes stored at ∼26 °C 75–82 % relative humidity for 25 days. Tomato fruits evaluated periodically after application coating materials. Results showed that coated with AL TE maintained better than uncoated Among various treatments, resulted in delayed weight loss (3.25 %), ripening...
Correct classification of type 1 (T1D) and 2 diabetes (T2D) is challenging due to overlapping clinical features the increasingly early onset T2D, particularly in South Asians. Polygenic risk scores (PRSs) for T1D T2D have been shown work relatively well Asians, despite being derived from largely European-ancestry samples. Here we used PRSs investigate rate potential misclassification amongst British Bangladeshis Pakistanis. Using linked health records Genes & Health cohort (n = 38,344)...
Background: In recent years, transdermal drug delivery systems (TDDS) have gained popularity as a non-invasive, patient-friendly medication method. Objective: This review article examines the latest developments and breakthroughs. The begins with brief summary of administration, stressing skin's barrier role permeation methods. Novel materials methods improve solubility, stability, skin permeability in formulation technologies. Methods: A literature most innovations TDDS, such nano-based...
In search of potential therapeutics for cancer, we described herein the synthesis, characterization, and in vitro anticancer activity a novel series curcumin analogues. The effects were evaluated on panel 60 cell lines, according to National Cancer Institute (NCI) screening protocol. There 10 tested compounds among 14 synthesized compounds, which showed potent both one-dose 5-dose assays. most active compound was 3,5-bis(4-hydroxy-3-methylstyryl)-1 H -pyrazole-1-yl(phenyl)methanone ( ) mean...
Peroxisome proliferator-activated receptor γ (PPARγ) has received significant attention as a key regulator of glucose and lipid homeostasis. In this study, we synthesized tested library novel 5-benzylidene-thiazolidin-2,4-dione (BTZD) derivatives bearing substituent on nitrogen TZD nucleus (compounds 1a-1k, 2i-10i, 3a, 6a, 8a-10a). Three compounds (1a, 1i, 3a) exhibited selectivity towards PPARγ were found to be weak moderate partial agonists. Surface Plasmon Resonance (SPR) results...