Rohini Mathur
A5014459421- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Chronic Disease Management Strategies
- Health disparities and outcomes
- Migration, Health and Trauma
- Genetic Associations and Epidemiology
- Long-Term Effects of COVID-19
- Diabetes Management and Education
- SARS-CoV-2 and COVID-19 Research
- Primary Care and Health Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- Global Health Workforce Issues
- Liver Disease Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- COVID-19 epidemiological studies
- Climate Change and Health Impacts
- COVID-19 and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Vaccine Coverage and Hesitancy
- Clinical practice guidelines implementation
- Atrial Fibrillation Management and Outcomes
- Chronic Kidney Disease and Diabetes
- Influenza Virus Research Studies
Queen Mary University of London
2016-2025
Wolfson Medical Center
2025
University of London
2011-2024
London School of Hygiene & Tropical Medicine
2015-2024
University College London
2021-2024
Universidad de Londres
2011-2024
Primary Health Care
2023
William Harvey Research Institute
2014-2023
Landscape Research Group
2023
Wellcome Sanger Institute
2023
The Clinical Practice Research Datalink (CPRD) is an ongoing primary care database of anonymised medical records from general practitioners, with coverage over 11.3 million patients 674 practices in the UK.With 4.4 active (alive, currently registered) meeting quality criteria, approximately 6.9% UK population are included and broadly representative terms age, sex ethnicity.General practitioners gatekeepers specialist referrals UK.The CPRD therefore a rich source health data for research,...
Abstract Background Establishing who is at risk from a novel rapidly arising cause of death, and why, requires new approach to epidemiological research with very large datasets timely data. Working on behalf NHS England we therefore set out deliver secure pseudonymised analytics platform inside the data centre major primary care electronic health records vendor establishing coverage across detailed for substantial proportion all patients in England. The following results are preliminary....
<h2>Summary</h2><h3>Background</h3> COVID-19 has disproportionately affected minority ethnic populations in the UK. Our aim was to quantify differences SARS-CoV-2 infection and outcomes during first second waves of pandemic England. <h3>Methods</h3> We conducted an observational cohort study adults (aged ≥18 years) registered with primary care practices England for whom electronic health records were available through OpenSAFELY platform, who had at least 1 year continuous registration start...
Abstract The frequency of, and risk factors for, long COVID are unclear among community-based individuals with a history of COVID-19. To elucidate the burden possible causes in community, we coordinated analyses survey data from 6907 self-reported COVID-19 10 UK longitudinal study (LS) samples 1.1 million diagnostic codes electronic healthcare records (EHR) collected by spring 2021. Proportions presumed cases LS reporting any symptoms for 12+ weeks ranged 7.8% 17% (with 1.2 to 4.8%...
BackgroundEthnicity recording across the National Health Service (NHS) has improved dramatically over past decade. This study profiles completeness, consistency and representativeness of routinely collected ethnicity data in both primary care hospital settings.
Objectives UK Biobank is a UK-wide cohort of 502,655 people aged 40–69, recruited from National Health Service registrants between 2006–10, with healthcare data linkage. Type 2 diabetes key exposure and outcome. We developed algorithms to define prevalent incident for Biobank. The will be implemented by their results made available researchers on request. Methods used self-reported medical history medication assign type, tested this against linked primary secondary care in Welsh...
<ns4:p><ns4:bold>Background</ns4:bold>: International and UK data suggest that Black, Asian Minority Ethnic (BAME) groups are at increased risk of infection death from COVID-19. We aimed to explore the in minority ethnic England using reported by NHS England.</ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>: used on patients with a positive COVID-19 test who died hospitals published 28th April, deaths ethnicity available 1st March 2020 up 5pm 21 April 2020. undertook indirect standardisation...
BackgroundThere are concerns that the response to COVID-19 pandemic in UK might have worsened physical and mental health, reduced use of health services. However, scale problem is unquantified, impeding development effective mitigations. We aimed ascertain what has happened general practice contacts for acute outcomes during pandemic.MethodsUsing de-identified electronic records from Clinical Research Practice Datalink (CPRD) Aurum (covering 13% population), between 2017 2020, we calculated...
BackgroundTo effectively prevent, detect, and treat health conditions that affect people during their lifecourse, health-care professionals researchers need to know which sections of the population are susceptible at ages. Hence, we aimed map course human by identifying 50 most common in each decade life estimating median age first diagnosis.MethodsWe developed phenotyping algorithms codelists for physical mental involve intensive use resources. Individuals older than 1 year were included...
National and global recommendations for BMI cutoffs to trigger action prevent obesity-related complications like type 2 diabetes among non-White populations are questionable. We aimed prospectively identify ethnicity-specific obesity based on the risk of that risk-equivalent cutoff White (≥30 kg/m2).In this population-based cohort study, we used electronic health records across primary care (Clinical Practice Research Datalink) linked secondary (Hospital Episodes Statistics) from a network...
<ns4:p><ns4:bold>Background</ns4:bold>: International and UK data suggest that Black, Asian Minority Ethnic (BAME) groups are at increased risk of infection death from COVID-19. We aimed to explore the in minority ethnic England using reported by NHS England.</ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>: used on patients with a positive COVID-19 test who died hospitals published 28th April, deaths ethnicity available 1st March 2020 up 5pm 21 April 2020. undertook indirect standardisation...
The SARS-CoV-2 B.1.1.7 variant of concern (VOC) is increasing in prevalence across Europe. Accurate estimation disease severity associated with this VOC critical for pandemic planning. We found increased risk death compared non-VOC cases England (hazard ratio: 1.67; 95% confidence interval: 1.34–2.09; p < 0.0001). Absolute by 28 days age and comorbidities. This has potential to spread faster higher mortality than the date.
Background Long COVID describes new or persistent symptoms at least 4 weeks after onset of acute COVID-19. Clinical codes to describe this phenomenon were recently created. Aim To the use long-COVID codes, and variation by general practice, demographic variables, over time. Design setting Population-based cohort study in English primary care. Method Working on behalf NHS England, OpenSAFELY data used encompassing 96% population between 1 February 2020 25 May 2021. The proportion people with...
The risk of severe COVID-19 outcomes in people with immune-mediated inflammatory diseases and on immune-modifying drugs might not be fully mediated by comorbidities vary factors such as ethnicity. We aimed to assess the adults those therapies.
Globally, there is a paucity of multimorbidity and comorbidity data, especially for minority ethnic groups younger people. We estimated the frequency common disease combinations identified non-random associations all ages in multiethnic population.In this population-based study, we examined patterns stratified by ethnicity or race, sex, age 308 health conditions using electronic records from individuals included on Clinical Practice Research Datalink linked with Hospital Episode Statistics...
Social prescribing is targeted at isolated and lonely patients. Practitioners patients jointly develop bespoke well-being plans to promote social integration or reactivation. Our aim was investigate: whether a service could be implemented in general practice (GP) setting evaluate its effect on primary care resource use.We used mixed method evaluation approach using patient surveys with matched control groups qualitative interview study. The study conducted socio-economic, multi-ethnic, inner...
<h3>Objectives</h3> To describe trends in the incidence and prevalence of diabetic retinopathy (DR) UK by diabetes type, age, sex, ethnicity, deprivation, region calendar year. <h3>Design</h3> Cohort study using Clinical Practice Research Datalink (CPRD). <h3>Setting</h3> primary care. <h3>Participants</h3> 7.7 million patients ≥12 contributing to CPRD from 2004 2014. <h3>Primary secondary outcome measures</h3> Age-standardised diabetes, DR severe (requiring photocoagulation) year population...
Abstract Objective To assess the association between learning disability and risk of hospital admission death from covid-19 in England among adults children. Design Population based cohort study on behalf NHS using OpenSAFELY platform. Setting Patient level data were obtained for more than 17 million people registered with a general practice that uses TPP software. Electronic health records linked Office National Statistics Secondary Uses Service. Participants Adults (aged 16-105 years)...
Background The "healthy obese" hypothesis suggests the risks associated with excess adiposity are reduced in those higher muscle quality (mass/strength). Alternative possibilities include loss of as people become unwell (reverse causality) or unmeasured confounding. Methods and Results We conducted a cohort study using UK Biobank (n=452 931). Baseline body mass index ( BMI) was used to quantify handgrip strength HGS ) for quality. Outcomes were fatal non-fatal cardiovascular disease,...
Ethnic minorities have experienced disproportionate COVID-19 mortality rates in the UK and many other countries. We compared differences risk of related death between ethnic groups first second waves pandemic England. also investigated whether factors explaining changed two waves. Using data from Office for National Statistics Public Health Data Asset, a linked dataset combining 2011 Census with primary care hospital records registrations, we conducted an observational cohort study to...