A5080329288- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Health disparities and outcomes
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Global Health Care Issues
- Employment and Welfare Studies
- Migration, Health and Trauma
- Climate Change and Health Impacts
- Chronic Disease Management Strategies
- Labor market dynamics and wage inequality
- Youth Education and Societal Dynamics
- Frailty in Older Adults
- Education Systems and Policy
- Intergenerational and Educational Inequality Studies
- Mental Health Treatment and Access
- Suicide and Self-Harm Studies
- Food Security and Health in Diverse Populations
- Retirement, Disability, and Employment
- Infection Control and Ventilation
- COVID-19 Impact on Reproduction
- Health Systems, Economic Evaluations, Quality of Life
Office for National Statistics
2020-2025
University of Southampton
2025
London School of Economics and Political Science
2024
London School of Hygiene & Tropical Medicine
2020-2024
Government of the United Kingdom
2020-2023
Faculty of Public Health
2021-2023
University of London
2021-2023
King's College School
2019-2022
King's College London
2014-2022
Royal Society of Tropical Medicine and Hygiene
2021-2022
Abstract Objective To quantify rates of organ specific dysfunction in individuals with covid-19 after discharge from hospital compared a matched control group the general population. Design Retrospective cohort study. Setting NHS hospitals England. Participants 47 780 (mean age 65, 55% men) and discharged alive by 31 August 2020, exactly to controls pool about 50 million people England for personal clinical characteristics 10 years electronic health records. Main outcome measures Rates...
Abstract Objective To estimate associations between covid-19 vaccination and long covid symptoms in adults with SARS-CoV-2 infection before vaccination. Design Observational cohort study. Setting Community dwelling population, UK. Participants 28 356 participants the Office for National Statistics COVID-19 Infection Survey aged 18-69 years who received at least one dose of an adenovirus vector or mRNA vaccine after testing positive infection. Main outcome measure Presence 12 weeks over...
Objectives To estimate the impact of COVID-19 pandemic on cancer care services and overall (direct indirect) excess deaths in people with cancer. Methods We employed near real-time weekly data to determine adverse effect services. also used these data, together national death registrations until June 2020 model deaths, background (pre-COVID-19) mortality, Background mortality risks for 24 cancers without COVID-19-relevant comorbidities were obtained from population-based primary cohort...
Abstract Objective To assess the risk of covid-19 death after infection with omicron BA.1 compared delta (B.1.617.2). Design Retrospective cohort study. Setting England, United Kingdom, from 1 December 2021 to 30 2021. Participants 035 149 people aged 18-100 years who tested positive for SARS-CoV-2 under national surveillance programme and had an identified as or compatible. Main outcome measures The main measure was certification records. exposure interest variant NHS Test Trace PCR tests...
Abstract This paper provides novel evidence on how a sharp increase in labor force participation among older women affects the provision of informal care to their parents. Based data from Understanding Society – The UK Household Longitudinal Study, we use an instrumental variable approach that exploits unique reform increased female State Pension age by up six years. Our results provide trade‐off between intensive margin work and provided outside household: 10 hours per week reduces 2.1...
We investigated long COVID incidence by vaccination status in a random sample of UK adults from April 2020 to November 2021. Persistent symptoms were reported 9.5% 3090 breakthrough severe acute respiratory syndrome coronavirus 2 infections and 14.6% unvaccinated controls (adjusted odds ratio, 0.59 [95% confidence interval, .50-.69]), emphasizing the need for public health initiatives increase population-level vaccine uptake.
Abstract Aims Cardiovascular diseases (CVDs) increase mortality risk from coronavirus infection (COVID-19). There are also concerns that the pandemic has affected supply and demand of acute cardiovascular care. We estimated excess in specific CVDs, both ‘direct’, through infection, ‘indirect’, changes healthcare. Methods results used (i) national data for England Wales to investigate trends non-COVID-19 CVD deaths; (ii) routine hospitals (n = 2), Italy 1), China 5) assess indirect effects on...
Objectives To estimate occupational differences in COVID-19 mortality and test whether these are confounded by factors such as regional differences, ethnicity education or due to non-workplace factors, deprivation prepandemic health. Methods Using a cohort study of over 14 million people aged 40–64 years living England, we analysed death involving COVID-19, assessed between 24 January 2020 28 December 2020. We estimated age-standardised rates (ASMRs) per 100 000 person-years at risk...
Ethnic minorities have experienced disproportionate COVID-19 mortality rates in the UK and many other countries. We compared differences risk of related death between ethnic groups first second waves pandemic England. also investigated whether factors explaining changed two waves. Using data from Office for National Statistics Public Health Data Asset, a linked dataset combining 2011 Census with primary care hospital records registrations, we conducted an observational cohort study to...
Objective To estimate the proportion of ethnic inequalities explained by living in a multi-generational household. Design Causal mediation analysis. Setting Retrospective data from 2011 Census linked to Hospital Episode Statistics (2017-2019) and death registration (up 30 November 2020). Participants Adults aged 65 years or over private households England 2 March 2020 until (n=10,078,568). Main outcome measures Hazard ratios were estimated for COVID-19 people household compared with another...
To examine inequalities in COVID-19 vaccination rates among elderly adults England.Cohort study.People living private households and communal establishments England.6 655 672 aged ≥70 years (mean 78.8 years, 55.2% women) who were alive on 15 March 2021.Having received the first dose of a vaccine against by 2021. We calculated estimated unadjusted adjusted ORs using logistic regression models.By 2021, 93.2% people England 70 over had at least one vaccine. While differed across all factors...
Abstract Objectives The epidemiology of post-COVID syndrome (PCS) is currently undefined. We quantified rates organ-specific impairment following recovery from COVID-19 hospitalisation compared with those in a matched control group, and how the rate ratio (RR) varies by age, sex, ethnicity. Design Observational, retrospective, cohort study. Setting NHS hospitals England. Participants 47,780 individuals (mean age 65 years, 55% male) hospital discharged alive 31 August 2020, to controls on...
Background The UK began an ambitious COVID-19 vaccination programme on 8 December 2020. This study describes variation in uptake by sociodemographic characteristics between 2020 and August 2021. Methods Using population-level administrative records linked to the 2011 Census, we estimated monthly first dose rates age group among adults aged 18 years or over England. We also present a tool display results interactively. Results Our sample included 35 223 466 adults. A lower percentage of males...
Background We aimed to determine whether children and adults with poorly controlled or more severe asthma have greater risk of hospitalisation and/or death from COVID-19. Methods used individual-level data the Office for National Statistics Public Health Data Asset, based on 2011 census in England, General Practice Extraction Service pandemic planning research linked registration records Hospital Episode admission data. Adults were followed 1 January 2020 30 September 2021 For children, only...
Abstract Obesity and ethnicity are known risk factors for COVID-19 outcomes, but their combination has not been extensively examined. We investigate the association between body mass index (BMI) mortality across different ethnic groups using linked national Census, electronic health records data adults in England from start of pandemic (January 2020) to December 2020. There were 30,067 (0.27%), 1,208 (0.29%), 1,831 845 (0.18%) deaths white, Black, South Asian other minority groups,...
Abstract Several studies have reported associations between COVID-19 vaccination and risk of cardiac diseases, especially in young people; the impact on mortality, however, remains unclear. We use national, linked electronic health data England to assess positive SARS-CoV-2 tests all-cause mortality people (12 29 years) using a self-controlled case series design. Here, we show there is no significant increase or 12 weeks following compared more than after any dose. However, find an death...
Abstract Background Evidence on the long-term employment consequences of SARS-CoV-2 infection is lacking. We used data from a large, community-based sample in UK to estimate associations between Long Covid and outcomes. Methods This was an observational, longitudinal study using pre–post design. included survey participants 3 February 2021 30 September 2022 when they were aged 16–64 years not education. Using conditional logit modelling, we explored time-varying relationship status ≥12 weeks...
We estimated population-level associations between ethnicity and coronavirus disease 2019 (COVID-19) mortality using a newly linked census-based data set investigated how ethnicity-specific risk evolved during the pandemic.We conducted retrospective cohort study of respondents to 2011 Census England Wales in private households, death registrations adjusted for emigration (n = 47 872 412). The outcome interest was involving COVID-19 2 March 2020 15 May 2020. hazard ratios (HRs)...
Despite generally high coronavirus disease 2019 (COVID-19) vaccination rates in the UK, hesitancy and lower take-up have been reported certain ethnic minority communities.We used data from National Immunisation Management System (NIMS) linked to 2011 Census individual health records for subjects aged ≥40 years (n = 24 094 186). We estimated age-standardized rates, stratified by group key sociodemographic characteristics, such as religious affiliation, deprivation, educational attainment,...
Public policy measures and clinical risk assessments relevant to COVID-19 need be aided by prediction models that are rigorously developed validated. We aimed externally validate a algorithm (QCovid) estimate mortality outcomes from in adults England.We did population-based cohort study using the UK Office for National Statistics Health Linked Data Asset, of individuals aged 19-100 years, based on 2011 census linked Hospital Episode Statistics, General Practice Extraction Service data...
Background Exposure to SARS-CoV-2, subsequent development of COVID-19 and death from may vary by occupation, the risks be higher for those categorised as ‘essential workers’. Methods We estimated excess mortality occupational group sex separately each month in 2020 entire 12 months overall. Results Mortality all adults working age was similar annual average over previous 5 years. Monthly peaked April, when number deaths 54.2% than expected lowest December were 30.0% lower expected. Essential...
To assess the association between household size and risk of non-severe or severe COVID-19.