Shailendra Bhatt

ORCID: 0000-0001-6928-2331
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About
Contact & Profiles
Research Areas
  • Nanoparticle-Based Drug Delivery
  • Advancements in Transdermal Drug Delivery
  • Stress Responses and Cortisol
  • Nanoparticles: synthesis and applications
  • Graphene and Nanomaterials Applications
  • Tryptophan and brain disorders
  • Drug Solubulity and Delivery Systems
  • Advanced Drug Delivery Systems
  • Parathyroid Disorders and Treatments
  • Neuroendocrine regulation and behavior
  • RNA Interference and Gene Delivery
  • Phytochemistry and Bioactivity Studies
  • Thyroid and Parathyroid Surgery
  • Olfactory and Sensory Function Studies
  • Electrospun Nanofibers in Biomedical Applications
  • Cholinesterase and Neurodegenerative Diseases
  • Laser-Ablation Synthesis of Nanoparticles
  • Hydrogels: synthesis, properties, applications
  • Advanced Polymer Synthesis and Characterization
  • Crystallization and Solubility Studies
  • Advanced biosensing and bioanalysis techniques
  • Biosensors and Analytical Detection
  • Ocular Surface and Contact Lens
  • Moringa oleifera research and applications
  • Quantum Dots Synthesis And Properties

GD Goenka University
2021-2023

B.J. Medical College
2015-2016

Nanotechnology is indisputably a scientific technique that offers the prospect of new therapies, and hope, for treatment malignant illnesses. It novel technology approaches diagnosis management diverse diseases. Although discovery Quantum dots (QD) nano-transporters has already led to few positive developments, QD are still at their initial stage, though have yet proven valuable society. The excertion indicates conversion in natural imaging along with photograph established incredible...

10.3389/fmats.2021.798440 article EN cc-by Frontiers in Materials 2022-01-10

In the past, curcumin was go-to medication for diabetes, but recent studies have shown that tetrahydrocurcumin is more effective. The problem it's not very soluble in water or bioavailable. So, our research aims to increase bioavailability and anti-diabetic efficacy of streptozotocin-induced diabetic rats by synthesizing tetrahydrocurcumin-loaded solid lipid nanoparticles. Box Behnken Design employed optimization nanoparticles (THC-SLNs). optimal formulation determined doing an ANOVA examine...

10.1016/j.jsps.2023.101727 article EN cc-by-nc-nd Saudi Pharmaceutical Journal 2023-08-02

Low penetration efficiency and retention time are the main therapeutic concerns that make it difficult for most of drugs to be delivered intraocular tissues. These challenging issues often related those drugs, which have low or poor solubility permeability. The goal this study was designed develop nanostructured lipid carriers (NLCs) loaded with itraconazole (ITZ) objective enhancing topical ocular permeation thereby improving clinical efficacy.

10.1016/j.sjbs.2021.11.006 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2021-11-12

A large number of current studies indicate that inflammatory mediators may contribute to depression in experimental models as well human beings. Nevertheless, the subject, whether anti-inflammatory treatments can prevent still remains controversial. In present study, a chronic mild stress (CMS) model male Sprague Dawley rats was used investigate role drugs treatment depression. All animals different groups, except normal control group, were exposed CMS procedure for 28 days and concurrently...

10.1111/bcpt.12539 article EN Basic & Clinical Pharmacology & Toxicology 2015-12-09

Abstract: The green synthesis approach using plants for the formation of metal/metal oxide nanoparticles is biologically safe and environment-friendly as compared to various physical chemical methods. Various phytoconstituents present in plants, such phenols, flavonoids, alkaloids, tannins, proteins, act potential bioresources nanoparticles. most common metals/metal oxides used are silver (Ag), copper (Cu), zinc, iron, gold. Amongst them, a comparably cheap metal than gold silver. Copper...

10.2174/1574885518666230328150208 article EN Current Drug Therapy 2023-03-30

Accumulating data advocates that inflammatory mediators may contribute to depression in experimental models as well humans. Nonetheless, whether anti-inflammatory treatments can prevent still remains controversial. To substantiate our hypothesis, we used an interferon-α-2b model of using Sprague Dawley rats. Interferon-α-2b is a cytokine which activates immune response and also produces depression. The animals were treated for 21 days with aspirin (10 mg/kg, per oral (p.o.)) dexamethasone (1...

10.1111/1440-1681.12660 article EN Clinical and Experimental Pharmacology and Physiology 2016-08-25

Nanotechnology has gained enormous attention in pharmaceutical research. is used the development of nanoparticles with sizes ranging from 1-100 nm, several extraordinary features. Metallic (MNPs) are various areas, such as molecular biology, biosensors, bio imaging, biomedical devices, diagnosis, pharmaceuticals, etc., for their specific applications.

10.2174/1872210517666230901114421 article EN Recent Patents on Nanotechnology 2023-09-08

Background: Nanotechnology has been considered an auspicious approach over the last twenty years and numerous researchers are making efforts to extend its applications in pharmaceuticals. Recently, various nano-based drug delivery systems, such as nanoparticles, nanoemulgel, nanosuspension, nanoemulsion, have developed deliver varieties of hydrophobics target sites. Rosuvastatin is a competitive inhibitor 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase enzyme. The application rosuvastatin...

10.2174/1574885517666220822104652 article EN Current Drug Therapy 2022-08-23

Background: Microspheres are controlled drug delivery systems (CDDS) because they have the potential to encapsulate various drugs, nucleic acids, and proteins. Their benefits include biocompatiblity, greater bioavailability, release. Presently, existing antiulcer agents suffer from severe side effects which restricted their utility encouraged requirement of a harmless proficient new agent. The rationale present research work was absorb in stomach for better fewer effects. Objective: current...

10.2174/2210303112666220602123548 article EN Drug Delivery Letters 2022-06-03

Background: Rivastigmine Tartrate belongs to the class of cholinesterase inhibitors in Anti-alzheimer’s disease with optimum therapeutic efficacy. Till now no validated method its quantification has been reported simulated nasal fluid. Objective: The current research investigation aims develop a rapid, simple, and reliable UV spectrophotometric for quantitative determination pure form SNF. Method: A suitable was developed by using double beam spectrophotometer selection solvent system...

10.13005/bpj/2314 article EN Biomedical & Pharmacology Journal 2021-12-30
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