A5085297893- Bone Tissue Engineering Materials
- biodegradable polymer synthesis and properties
- Orthopaedic implants and arthroplasty
- Graphene and Nanomaterials Applications
- Dental materials and restorations
- Inorganic Chemistry and Materials
- Dental Implant Techniques and Outcomes
AGH University of Krakow
2019-2024
Jagiellonian University
2023-2024
Development of new composite materials for bone tissue engineering is a constantly growing field medicine. Therefore there continuous need in creating novel that can not only regenerate the defected but also nourish it while healing process progresses. Here we present type material fulfils these requirements. The study describes creation with macroporous bioceramic core infiltrated thin biopolymer layer. ceramic component, namely tricalcium phosphate (TCP), due to its mechanistic and...
Implantations in orthopedics are associated with a high risk of bacterial infections the surgery area. Therefore, biomaterials containing antibacterial agents, such as antibiotics, bactericidal ions or nanoparticles have been intensively investigated. In this work, silver decorated β tricalcium phosphate (βTCP)-based porous scaffolds were obtained and coated biopolymer—poly(3-hydroxybutyrate)-P(3HB). To best our knowledge, studies using silver-doped βTCP P(3HB), component ceramic-polymer for...
Nowadays, regenerative medicine faces a major challenge in providing new, functional materials that will meet the characteristics desired to replenish and grow new tissue. Therefore, this study presents ceramic-polymer composites which matrix consists of tricalcium phosphates covered with blends containing chemically bounded diclofenac biocompatible polymer—poly(3-hydroxyoctanoate), P(3HO). Modification P(3HO) oligomers was confirmed by NMR, IR XPS. Moreover, obtained their were subjected an...
The search for new materials bone regenerative purposes is still ongoing. Therefore, we present a series of newly constructed composites based on β tricalcium phosphate (βTCP) and poly(3-hydroxybutyrate) bacteria-derived biopolymer (P(3HB)) in the form 3D scaffolds with different pore sizes. To improve polymer attachment to βTCP surface, etching ceramic sinters, using citric acid, was applied. As expected, pre-treatment led increase surface roughness creation micropores facilitating...
Polyhydroxyalkanoates (PHAs) are biocompatible and biodegradable bacterial-origin polyesters, which have recently emerged as a potential prosperous coating for bioceramic scaffolds. However, biopolymers often properties inferior to commercially available polymers, thus blending seems be an efficient method tailor their characteristics. In our study poly(3-hydroxybutyrate) (P(3HB)) medium chain length PHA (mcl-PHA) blends were used coatings on β tricalcium phosphate (βTCP) The influence of...