A5019457030- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Cardiovascular Syncope and Autonomic Disorders
- Hemodynamic Monitoring and Therapy
- Effects of Vibration on Health
- Cardiovascular and exercise physiology
- Ergonomics and Musculoskeletal Disorders
- Nerve injury and regeneration
- Alzheimer's disease research and treatments
- Neuroscience and Neuropharmacology Research
- Cholinesterase and Neurodegenerative Diseases
- Parkinson's Disease Mechanisms and Treatments
- Noise Effects and Management
- Pregnancy and preeclampsia studies
- Cardiovascular Health and Disease Prevention
- Cancer Risks and Factors
- Spaceflight effects on biology
- Muscle activation and electromyography studies
- Gestational Diabetes Research and Management
- Blood Pressure and Hypertension Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Cardiac Health and Mental Health
- Nuclear Receptors and Signaling
- Neurological disorders and treatments
- Balance, Gait, and Falls Prevention
Mossakowski Medical Research Institute, Polish Academy of Sciences
2014-2024
Polish Academy of Sciences
2013-2024
Central Clinical Hospital
2020
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego
2011-2019
Podhale State Higher Vocational School in Nowy Targ
2017-2019
Warsaw University of Technology
2012
Medical University of Warsaw
2009
Determination and Prediction of One Repetition Maximum (1RM): Safety Considerations Strength training is recommended for slowing age-dependent deterioration muscular strength rehabilitating patients with muscle weakening illnesses. Reliable assessment important proper design regimes prevention, rehabilitation, sport. repetition maximum (1RM) an established measure defined as the value resistance against which a given movement can be performed only once. Proper 1RM time consuming, may lead to...
In clinical trials for Alzheimer's disease (AD), hydromethylthionine mesylate (HMTM) showed reduced efficacy when administered as an add-on to symptomatic treatments, while it produced a significant improvement of cognitive function taken monotherapy. Interference cholinesterase inhibition with HMTM was observed also in tau transgenic mouse model, where rivastigmine the pharmacological activity at multiple brain levels including hippocampal acetylcholine release, synaptosomal glutamate...
Wingate test is short anaerobic exercise, performed with maximal power, whereas aerobic exercise at 85% heart rate (HR(max)) may be for long period. Sustained HR elevations and changes in autonomic activity indices have been observed after latter kind of exercise. Several studies reported reduction mean interval between consecutive R peaks ECG (RRI) 1 h test; however, underlying remain elusive. In eight young males, RRI variability (HRV) were measured daily over two 5-day trials. Subjects...
Summary Strength training is a recommended measure against loss of strength and muscle mass because age‐ or illness‐induced inactivity. exercises may impose heavy cardiovascular load by increasing heart rate blood pressure. To increase efficiently, has to be applied; this, however, leads spontaneous Valsalva manoeuvre, which additionally raises Avoidance this manoeuvre recommended. If the additional rise in arterial pressure caused smaller than intrathoracic intracranial pressures during...
Physical training confers protection to dopaminergic neurons in rodent models of parkinsonism produced by neurotoxins. The sparing effect physical on can be tested with applied during chronic MPTP treatment, while the neurorestorative when is after completing such treatment. In this study, onset respective treatment was specifically addressed. Three groups mice were injected 10 doses (12.5 mg/kg/injection) over 5 weeks. first group remained sedentary; second one underwent early training,...
Background: Little is known about the influence of dynamic training on hemodynamic and neurohormonal responses to static exercise inflammatory markers in optimally treated post-coronary artery bypass grafting (CABG) patients. Methods Results: One hundred twenty male patients, aged 55±6 years, 3 months after receiving CABG, were randomized either 6 weeks aerobic a cycloergometer, times week, at 70-80% maximum tolerated heart rate (HR) (training group, n=60) or control group (n=60). At...
Background: Little is known about the influence of aerobic training on neurohormonal and hemodynamic responses to head-up tilt (HUT) autonomic balance at rest after exercise in optimally treated, low risk post-coronary artery bypass grafting (CABG) patients. Methods: One hundred male patients, mean age 56 ± 6 years, 3 months CABG, were randomized either 6-week cycloergometer, times a week, 70–80% max tolerated heart rate (HR) (training group, n = 50) or control group (n 50). At...
Our aim was to evaluate the differences in early hemodynamic response tilt test (HUTT) patients with and without syncope using impedance cardiography (ICG).One hundred twenty-six (72 female/48 male; 37 ±17 years) were divided into a group (HUTT(+), n = 45 patients) (HUTT(-), 81 patients). ECG ICG signals continuously recorded during whole examination, allowing calculation of heart rate (HR), stroke volume (SV), cardiac output (CO) for every beat. The parameters (averaged over 1 min) analyzed...
Interaction was examined of nitric oxide (NO) and cytochrome P-450 (CYP-450)-dependent arachidonic acid derivatives, 20-HETE EETs, in control arterial pressure (MABP) renal function. Modification this interaction by changing sodium intake also studied.On low, standard or high Na diet (LS, STD HS rats respectively) effects sequential blockade NO synthases (NOS) CYP-450 enzyme activity on MABP, blood flow (RBF, Transonic probe), medullary perfusion (MBF, laser-Doppler technique), tissue...
The aim of our work was to assess the usefulness maternal factors, ultrasound and placental function parameters during early pregnancy as predictors birth weight in populations healthy pregnant women suffering from pregestational diabetes.A study group comprised 97 160 with diabetes (PGDM, type 1), all singleton pregnancy. Ultrasound examination performed between weeks 11 14, 20 30 gestation, based on recommendations Polish Society Gynecologists Obstetricians, Ultrasonography Division. We...
Abstract In rodents, detection and quantification of motor impairments is difficult. The traction test (inverted grid with mice clinging to the underside) currently has no objective rating system. We here developed validated semi-automatic MATLAB script TracMouse for unbiased video-recorded movement patterns. High precision videos were analyzed by: (i) principal identification anatomical paw details frame-by-frame by an experimentally blinded rater; (ii) automatic retrieval proxies...