José Aquino‐Esperanza

ORCID: 0000-0002-2626-7593
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About
Contact & Profiles
Research Areas
  • Respiratory Support and Mechanisms
  • Intensive Care Unit Cognitive Disorders
  • Cell death mechanisms and regulation
  • Airway Management and Intubation Techniques
  • Tracheal and airway disorders
  • Chemotherapy-induced organ toxicity mitigation
  • Non-Invasive Vital Sign Monitoring
  • Toxin Mechanisms and Immunotoxins
  • Cardiac Arrest and Resuscitation
  • Respiratory viral infections research
  • Neonatal Respiratory Health Research
  • Anesthesia and Sedative Agents
  • Pectus Deformity Diagnosis and Treatment
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Anesthesia and Neurotoxicity Research
  • COVID-19 Clinical Research Studies
  • Influenza Virus Research Studies
  • Shoulder and Clavicle Injuries
  • Pneumonia and Respiratory Infections
  • Reconstructive Surgery and Microvascular Techniques
  • Family and Patient Care in Intensive Care Units
  • Erythrocyte Function and Pathophysiology
  • Topic Modeling
  • Phonocardiography and Auscultation Techniques
  • Cytokine Signaling Pathways and Interactions

Institute of Research and Innovation Parc Tauli
2019-2022

Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2020-2022

Instituto de Salud Carlos III
2020-2022

Universitat de Barcelona
2019-2022

Universitat Autònoma de Barcelona
2020

Deleted Institution
2020

Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno
2010-2014

National University of the Northeast
2008

Abstract Background ICU patients undergoing invasive mechanical ventilation experience cognitive decline associated with their critical illness and its management. The early detection of different phenotypes might reveal the involvement diverse pathophysiological mechanisms help to clarify role precipitating predisposing factors. Our main objective is identify in critically ill survivors 1 month after discharge using an unsupervised machine learning method, contrast them classical approach...

10.1186/s13054-020-03334-2 article EN cc-by Critical Care 2020-10-21

OBJECTIVES: To characterize clusters of double triggering and ineffective inspiratory efforts throughout mechanical ventilation investigate their associations with mortality duration ICU stay ventilation. DESIGN: Registry-based, real-world study. Background: Asynchronies during invasive can occur as isolated events or in might be related to clinical outcomes. Subjects: Adults requiring greater than 24 hours for whom equal 70% ventilator waveforms were available. INTERVENTIONS: We identified...

10.1097/ccm.0000000000005471 article EN Critical Care Medicine 2022-02-04

Erythropoietic stress occurs under conditions of tissular hypoxia, such as anemia. Functional relationships between erythroid bone marrow (BM) proliferation, differentiation, the expression survival and apoptotic related proteins, well features BM microenvironment upon acute anemic stress, are not fully elucidated. To achieve this aim, CF-1 Swiss mice were injected with a single dose 5-fluorouracil (5-FU, 150 mg/kg ip) multiparametric analysis was conducted for 20 days. Apoptosis (TUNEL...

10.1016/j.cellbi.2008.04.014 article EN Cell Biology International 2008-04-11

Abstract Patient-ventilator asynchronies can be detected by close monitoring of ventilator screens clinicians or through automated algorithms. However, detecting complex patient-ventilator interactions (CP-VI), consisting changes in the respiratory rate and/or clusters asynchronies, is a challenge. Sample Entropy ( SE ) airway flow -Flow) and pressure -Paw) waveforms obtained from 27 critically ill patients was used to develop validate an algorithm for CP-VI. The algorithm’s performance...

10.1038/s41598-020-70814-4 article EN cc-by Scientific Reports 2020-08-17

Abstract Background Important clinical information of patients is present in unstructured free-text fields Electronic Health Records (EHRs). While this can be extracted using Natural Language Processing (cNLP), the recognition negation modifiers represents an important challenge. A wide range cNLP applications have been developed to detect medical entities free-text, however, effective solutions for languages other than English are scarce. This study aimed at developing a solution Spanish...

10.1186/s12911-023-02301-5 article EN cc-by BMC Medical Informatics and Decision Making 2023-10-13

Background: Minimally invasive repair of pectus excavatum (MIRPE) technique is the current most used surgical method for (PE) correction. To avoid MIRPE-required invasion mediastinum or pleural cavity, we developed taulinoplasty approach as an alternative option reduction sunken chest. Materials and Methods: This a single-center unblind nonrandomized prospective pilot study, involving 26 MIRPE 23 patients. The primary safety endpoint was presence complications, efficacy Haller index measured...

10.1089/lap.2021.0216 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2021-12-01

This was a pilot study to analyze the effects of tracheostomy on patient-ventilator asynchronies and respiratory system mechanics. Data were extracted from an ongoing prospective, real-world database that stores continuous output ventilators bedside monitors. Twenty adult subjects mechanical ventilation tracheostomized during ICU stay: 55% admitted for failure 35% neurologic conditions; median duration before 12 d; 16 d.We compared (the overall asynchrony index rates specific asynchronies)...

10.4187/respcare.08824 article EN Respiratory Care 2021-07-06
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