A5080388727- Circular RNAs in diseases
- MicroRNA in disease regulation
- Adipokines, Inflammation, and Metabolic Diseases
- Cancer-related molecular mechanisms research
- Lipoproteins and Cardiovascular Health
- Cardiovascular Disease and Adiposity
- Extracellular vesicles in disease
Shenzhen Luohu People's Hospital
2022-2025
Shenzhen University
2022
<title>Abstract</title> Diabetic peripheral neuropathic pain (DPNP) is a prevalent complication among diabetic patients. Recent studies have confirmed that ferroptosis, an iron-dependent cell death driven by lipid peroxidation, plays key role in DPNP development. However, biomarkers related to ferroptosis remain undiscovered. Core genes were identified using bioinformatics. By assessing the mechanical paw withdrawal threshold (PWT) and thermal latency (PWL), mouse model of was established,...
Circulating miRNAs are acclaimed biomarkers to predict the occurrence and progression of type 2 diabetes mellitus (T2DM). This study is aimed at analyzing correlation circulating miR-210 level obesity-associated T2DM then investigating underlying mechanism in T2DM.Totally, 137 serum samples from patients with were collected; meanwhile, demographic, general, clinical hematological characteristics, disease history, dietary patterns recorded. The exosomes was detected by qRT-PCR. Then,...