A5080878173- High Altitude and Hypoxia
- Phytochemical and Pharmacological Studies
- Medicinal plant effects and applications
- Thyroid Disorders and Treatments
- Medicinal Plants and Bioactive Compounds
- Growth Hormone and Insulin-like Growth Factors
- Neuroscience of respiration and sleep
- Botanical Studies and Applications
- Adipose Tissue and Metabolism
- Pharmacological Effects of Natural Compounds
- Muscle metabolism and nutrition
- Spaceflight effects on biology
- Sperm and Testicular Function
- Diet and metabolism studies
- Biochemical Acid Research Studies
- Birth, Development, and Health
- Travel-related health issues
- Hematological disorders and diagnostics
- Humic Substances and Bio-Organic Studies
- Thyroid and Parathyroid Surgery
- Microbial Natural Products and Biosynthesis
- Cynara cardunculus studies
- Ginseng Biological Effects and Applications
- Domain Adaptation and Few-Shot Learning
- Handwritten Text Recognition Techniques
Mohamed bin Zayed University of Artificial Intelligence
2023
Defence Institute of Physiology and Allied Sciences
1995-2009
Post Graduate Institute of Medical Education and Research
1974-1977
Army Hospital Research and Referral
1977
Sriram Chandra Bhanja Medical College Hospital
1974
Abstract Sea buckthorn berries from Hippophae rhamnoides, H. tibetana , and salicifolia were collected the cold deserts of Himalayas (Lahaul, Ladakh, Spiti; India) characterized in terms FA, carotenoid, tocopherol, tocotrienol composition their pulp oil. These varied species to species. Total carotenoids ranged 692 3420 mg/kg oils fresh berries, total tocols, 666 1788 mg/kg. contained substantially lower amounts oil, with levels tocopherols. There was little difference proportion individual...
In the present study, a poly-herbal formulation (PHF) was prepared by combining aqueous lyophilized leaf extracts of Hippophae rhamnoides L. and Aloe vera ethanol rhizome extract Curcuma longa L., in an optimized ratio (1 : 7 1). The efficacy PHF treatment studied normal impaired diabetic rats using full-thickness cutaneous wound model. Topical increased cellular proliferation collagen synthesis at site rats, as evidenced significant increase DNA, total protein, hydroxyproline, hexosamine...
Modulation of immune response to alleviate diseases has long since been interest. Plant extracts have widely investigated for their possible immunomodulatory properties. We evaluated the activity aqueous extract Rhodiola rhizome in human peripheral blood mononuclear cells (PBMCs) and mouse macrophage cell line RAW 264.7. The was found stimulate production interleukin-6 (IL-6) tumor necrosis factor-alpha (TNF-alpha) PBMCs as well 264.7 line. It also increased nitric oxide synergistically...
There are several reports, which suggest that the consumption of foods rich in flavonoids is associated with a lower incidence certain degenerative diseases, including cardiovascular disease. Flavones, Seabuckthorn (SBT) (Hippophae rhamnoides L.) fruit berry can modulate production and level signaling molecules immune function inflammation vitro, cytokines. We have evaluated immunomodulatory activity ethanolic solution SBT flavone (FLV) human peripheral blood mononuclear cells (PBMCs). The...
This study was designed to determine the cytoprotective activity of flavones seabuckthorn (Hippophae rhamnoides L.) against tert-butyl hydroperoxide (tert-BOOH), used as an oxidant induce oxidative damage, with lymphocytes model system. Addition tert-BOOH (250 μM) cells resulted in enhanced cytotoxicity and free radical production. The intracellular calcium levels, caspase activity, apoptosis were significantly increased following treatment. Seabuckthorn at concentration 100 μg/mL inhibited...
The alterations in serum levels of T3, T4, TSH and TBG, response to 100 mug iv TRH, urinary excretion T3 T4 were studied 8 healthy men at sea level (SL), on days 1, 2, 4, 16 after arrival by air high altitude (3,700 m, HA), during 5 7 their return SL. No significant TBG or TRH observed exposure HA There was, however, an acute elevation both total T4. Serum from a mean basal+/-SE value 128+/-13 ng/dl increased 320+/-18 day 1 remained significantly elevated 225+/-48 up altitude. Similarly...
In 25 patients suffering from fever of infection, serum levels thyrotropin (TSH), thyroxine (T4), triiodothyronine (T3), and binding globulin (TBG) were estimated on two consecutive days during the febrile period again 3 to 10 after had subsided. The TSH T3 responses 100 μi, give TRH also studied fever. Hormones by specific radioimmunoassays TBG radioligand assay. As compared with age sex matched normal controls, infection significantly lowered total TBG. T4 concentrations not altered....
Summary: Altitude induced alterations in circulatory levels of PRL, LH, FSH and testosterone were studied seven eugonadal men at sea level (SL), during their stay high altitude (HA, 3500 m) a week after return to SL. The mean plasma PRL SL was 5.83 ± 1.7 SE ng/ml. On day one arrival HA, the values 7.81 1.81 9.21 1.64 ng/ml respectively not significantly different (p > 0.05) than initial values. However, on 18 increased < 0.01) 17.68 1.82 returned within days A significant decrease LH...
Summary Objective Acute mountain sickness (AMS) characterized by presence of symptoms including headache, nausea, excessive fatigue, loss appetite, irritability and insomnia is a major impediment to work performance in human subjects who are rapidly inducted high altitude (HA) during the initial phase induction. The present study aims at evaluate efficacy prophylactic administration low dose glucocorticoids prevention AMS normal healthy men HA air. Design Fifty were randomly divided into...
High altitude-induced alterations in pituitary, gonadal and adrenal hormones were studied (i) eugonadal men from the armed forces who resident at sea level (SL), (ii) SL residents staying an altitude of 3542 m for periods ranging 3 to 12 months (acclimatized lowlanders, ALL), (iii) ALL stayed 6300 6 months, (iv) trekked 5080 more than glacier region (v) high-altitude natives (HAN) 3300-3700 m. Circulating levels LH, FSH, prolactin, cortisol, testosterone, dihydrotestosterone (DHT)...