A5076293095- High Altitude and Hypoxia
- Neuroscience of respiration and sleep
- Adipose Tissue and Metabolism
- Phytochemical and Pharmacological Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Neuroscience and Neuropharmacology Research
- Optical Wireless Communication Technologies
- Atmospheric aerosols and clouds
- Exercise and Physiological Responses
- Medicinal Plants and Bioactive Compounds
- Sleep and Wakefulness Research
- Biochemical effects in animals
- Medicinal Plants and Neuroprotection
- Tryptophan and brain disorders
- COVID-19 impact on air quality
- Medicinal plant effects and applications
- Phytochemicals and Medicinal Plants
- Neuroinflammation and Neurodegeneration Mechanisms
- Stress Responses and Cortisol
- Atmospheric Ozone and Climate
- Vitamin C and Antioxidants Research
- Botanical Studies and Applications
- Mitochondrial Function and Pathology
- Biochemical Acid Research Studies
- Semiconductor Lasers and Optical Devices
Defence Institute of Physiology and Allied Sciences
2006-2024
Ministry of Defence
2000-2024
Defence Institute of High Altitude Research
2024
Hindustan Institute of Technology and Science
2013-2023
Government of India
2006-2023
Withania somnifera root extract has been used traditionally in ayurvedic system of medicine as a memory enhancer. Present study explores the ameliorative effect withanolide A, major component withania and its molecular mechanism against hypoxia induced impairment. Withanolide A was administered to male Sprague Dawley rats before period 21 days pre-exposure during 07 exposure simulated altitude 25,000 ft. Glutathione level glutathione dependent free radicals scavenging enzyme system, ATP,...
Adverse environmental conditions such as hypobaric hypoxia (HH) cause memory impairment by affecting cellular machinery leading to neurodegeneration. Providing enriched environment (EE) is found be beneficial for curing several neurodegenerative disorders. The protective role of EE in preventing HH induced neuronal death has been reported previously but the involved mechanism still not clearly understood. present study an attempt verify impact on spatial during and also explore possible...