Mark A. Fletcher

ORCID: 0000-0002-2660-8730
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About
Contact & Profiles
Research Areas
  • Pneumonia and Respiratory Infections
  • Respiratory viral infections research
  • Bacterial Infections and Vaccines
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Influenza Virus Research Studies
  • Vaccine Coverage and Hesitancy
  • Vector-Borne Animal Diseases
  • Vector-borne infectious diseases
  • Viral Infections and Vectors
  • Immune Response and Inflammation
  • Emergency and Acute Care Studies
  • Viral gastroenteritis research and epidemiology
  • Immune Cell Function and Interaction
  • HIV Research and Treatment
  • Virology and Viral Diseases
  • Immunodeficiency and Autoimmune Disorders
  • Streptococcal Infections and Treatments
  • Clostridium difficile and Clostridium perfringens research
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Congenital Diaphragmatic Hernia Studies
  • Viral-associated cancers and disorders
  • Diabetes and associated disorders
  • T-cell and Retrovirus Studies
  • Reproductive tract infections research
  • Cervical Cancer and HPV Research

Pfizer (France)
2014-2025

Pfizer (United States)
2022

Pfizer (China)
2022

University of Maryland, Baltimore
2016

Baltimore City Health Department
2016

New York City Fire Department
2016

Institut de Recherche Vaccinale
2007

Institut Pasteur
2000-2001

Roquette Frères (France)
1996-1999

Harvard University
1996-1997

The chronic fatigue syndrome (CFS), formerly known as Epstein-Barr virus syndrome, is a clinical state of some complexity and uncertain etiology. In order to characterize in comprehensive manner the status laboratory markers associated with cellular immune function patients this 30 clinically defined CFS were studied. All subjects found have multiple abnormalities these markers. most consistent immunological abnormality detected among patients, when compared normal controls, was low natural...

10.1128/jcm.28.6.1403-1410.1990 article EN Journal of Clinical Microbiology 1990-06-01

In late 2007, some Swedish County Councils started 7-valent pneumococcal conjugate vaccine (PCV7) implementation for children, and PCV7 was included in the national immunization program 2009. By 2010, both PCV10 PCV13 were licensed, selection of subject to tenders. This study investigated impact order PCV introduction into vaccination programs on incidence all-cause pneumonia hospitalizations children <2 years-old.Using population-based data from publicly available National Inpatient...

10.1371/journal.pone.0112211 article EN cc-by PLoS ONE 2014-11-07

Streptococcus pneumoniae is the predominant otitis media pathogen and its prevention through effective vaccination could diminish childhood illness antibiotic use. This paper reviews 5 pneumococcal conjugate vaccine (PCV) trials that used as an endpoint: Northern California Kaiser Permanente (NCKP; vaccine, 7-valent PCV [PCV7]-CRM); Finnish Otitis Media (FinOM; vaccines, PCV7-CRM or PCV7-OMPC); Native American Trial (vaccine, PCV7-CRM); Pneumococcal Efficacy (POET; 11-valent [PCV11]-PD). For...

10.1155/2012/312935 article EN cc-by International Journal of Otolaryngology 2012-01-01

A clinicopathologic study of all cases accessioned as calcifying odontogenic cyst (COC) from 1971 to 1996 the files Oral Pathology Laboratory at Temple University School Medicine was undertaken.Microscopic slides and clinical histories diagnosed were reviewed analyzed. Ten processed for cytokeratin immunohistochemical staining.Fifty-seven reviewed, 28 males 29 females. Patients' ages ranged 7 83 years, with a mean age 49.8 years. Thirty-four involved mandible 23 maxilla. Seventeen reported...

10.1016/s0278-2391(97)90574-7 article EN cc-by-nc-nd Journal of Oral and Maxillofacial Surgery 1997-07-01

Our recent studies have demonstrated that in early HIV-1 infection, elevation of plasma immunoglobulin E (IgE) levels precedes the decline CD4 cell count and is influenced by vitamin status. In order to further investigate role IgE we determined HIV-1-seropositive -seronegative intravenous drug users (IDUs) (n = 38), relationship cellular humoral immune function, liver enzymes, To examine possible impact route infection on levels, comparisons between cohorts IDUs homosexual men 45) were also...

10.1111/j.1398-9995.1995.tb05073.x article EN Allergy 1995-02-01

To provide medical and social services to underserved communities, many health care organizations across the United States have expanded role of emergency include mobile integrated community paramedicine (MIH-CP). Although MIH-CP programs differ in structure setting, share common goal improving through home-based, patient-centered management models. Ideally, these innovative reduce use services, including 911 (US system) calls department visits. In 2018 a large, urban academic center...

10.1089/pop.2020.0038 article EN Population Health Management 2020-06-26
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