- Biosensors and Analytical Detection
- Electrospun Nanofibers in Biomedical Applications
- Microfluidic and Capillary Electrophoresis Applications
- 3D Printing in Biomedical Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Analytical Chemistry and Sensors
- Advanced biosensing and bioanalysis techniques
- Electrochemical Analysis and Applications
- Biochemical and Structural Characterization
- Microfluidic and Bio-sensing Technologies
- Membrane Separation Technologies
- Conducting polymers and applications
- Pluripotent Stem Cells Research
- Polymer composites and self-healing
- Advanced Sensor and Energy Harvesting Materials
- Bacterial Identification and Susceptibility Testing
- Glycosylation and Glycoproteins Research
- Electrochemical sensors and biosensors
- Phytoplasmas and Hemiptera pathogens
- Mycobacterium research and diagnosis
- Pleural and Pulmonary Diseases
- Boron Compounds in Chemistry
- Antibiotic Resistance in Bacteria
- Recycling and utilization of industrial and municipal waste in materials production
- Bacterial biofilms and quorum sensing
Eskişehir Osmangazi University
2017-2025
Ankara Yıldırım Beyazıt University
2020-2023
University of Strathclyde
2022
Abstract Investigation of the behavior biopolymers in flow such as Deoxyribonucleic acid (DNA), is a critical challenge engineering, polymer, and life sciences. In this study, we studied rheological properties DNA characteristics real-time. The velocity measurement was carried out using confocal detection incorporated with Fluorescence Correlation Spectroscopy (FCS). Optical experiments provided an understanding diffusion- flow-dominated regimes for molecules treated microfluidic channels...
Abstract Electrode-integrated microfluidic chips play a pivotal role in applying electrochemical impedance spectroscopy (EIS) across various domains. This technology has significantly transformed biomedical research, facilitating progress drug discovery, diagnostics, and cell analysis. The architecture of these integrated with electrodes critically influences the precision dependability EIS outcomes. study developed diverse chip designs, including circular, deltoid, deltoid-like shapes, to...
Cyclotides as a cyclic peptide produced by different groups of plants have been very attractive field research due to their exceptional properties in biological activities and drug design applications. The importance cyclotides new from nature caused attract researchers develop separation systems. Recent growth development on chip-based technology for bioassay especially anticancer having sparklingly advantages comparison with common traditional methods. In this study, the microfluidic Vigno...
Abstract Among the thermoplastic elastomers that play important roles in polymer industry due to their superior properties, styrene‐based species and polyurethane block copolymers are of great interest. Poly(styrene‐ethylene‐butadiene‐styrene) (SEBS) as a triblock copolymer seems have potential meet many demands different applications various industrial requirements where durability, biocompatibility, breaking elongation, interfacial adhesion important. In this study, SEBS was functionalized...
Biosensors are analytical tools used for the analysis of biomaterial samples and provide an understanding about biocomposition, structure, function biomolecules and/or biomechanisms by converting biological response into electrical optical signal. In particular, with rise in antibiotic resistance amongst pathogenic bacteria, study activity transport across cell membranes field biosensors has been gaining widespread importance. Herein, rapid label-free detection permeation a membrane,...
Abstract One quarter of the global population is thought to be latently infected by Mycobacterium tuberculosis (TB) with it estimated that 1 in 10 those people will go on develop active disease. Due fact M. a disease most often associated low‐ and middle‐income countries, critical low‐cost easy‐to‐use technological solutions are developed, which can have direct impact diagnosis prescribing practice for TB. area where intervention could particularly useful antibiotic susceptibility testing...
Permanent injury to corneal limbal stem cells after ocular surface chemical and thermal injuries is a major cause of blindness. In this study, PRP-laden GelMA hydrogel contact lens manufactured which aimed support the niche insults thereby preventing cell failure. with varying platelet-rich plasma (PRP) concentrations (5%, 10%, 20%) photopolymerized using visible light crosslinking system followed by characterizations mechanical properties, growth factor release, enzymatic degradation, in...
Coregulation of microRNAs (miRNAs) and cancer stem cells (CSCs) is very important in carcinogenesis. miR-127-5p known to be downregulated breast cancer. In this study, we aimed investigate how boric acid (BA), for its previously unstudied anti-cancer properties, would affect the expression miR127-5p genes responsible (BC-SCs) metastasis. BC-SCs were isolated from human (MCF-7) by immunomagnetic cell separation characterized with flow cytometry sphere formation. The viability determination...
Successful lysis of cells/microorganisms is a key step in the sample preparation fields like molecular biology, bioengineering, and biomedical engineering. This study therefore aims to investigate bacteria on-chip its dependence on both microfluidic channel structure flow rate. Effects temperature were also investigated. To perform these investigations, three different chips designed produced (straight, zigzag circular configurations), while length channels kept constant. As an exemplary...
Today, the emergence of antibiotic resistance in pathogenic bacteria is considered an important problem for society. Excessive consumption antibiotics, long-term treatments, and inappropriate prescriptions continually increase severity problem. Improving stewardship requires improved diagnostic testing, and, therefore, vitro susceptibility testing becoming increasingly important. This research details development test Mycobacterium smegmatis using streptomycin as antibiotics. strain was...
Mesenchymal stem cells (MSCs) are multipotent that can support various tissues including bone marrow, adipose tissue, and synovial fluids, from which they be readily isolated. The objective of this study is to harness the advantages microfluidic systems for controlling enhancing maintenance viability, regenerative properties MSCs by providing a 3D culture microenvironment with gelatin methacrylate (GelMA) hydrogel exposing slow fluid flow low shear stress conditions. GelMA has methacryloyl...
Abstract Electrochemical impedance spectroscopy is often used for biomolecular detection based on the interaction of a molecule with receptor functionalised electrode surface and consequent change. Though its performance well established, there still need improved sensitivity specificity, especially when attempting to detect nucleic acids from clinical samples minimal amplification steps. Localised heating potential approach improving hybridisation rates reducing non-specific interactions,...
The rapid growth of industry with increasing environmental pollution and abnormal climate changes caused by global warming leading to reduce water resources. It has encouragedstrengthening the science research protect clean drinking resources since last 40 years. As a result, many different technologies researches such as biologicaltreatment oxidation techniques related treatment are being carried out. In this study, color removal containing methylene blue (MB) using activated carbon was...