Chew Yee Tan

ORCID: 0000-0002-2674-3959
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Animal Virus Infections Studies
  • Virus-based gene therapy research
  • Viral Infections and Immunology Research
  • Microbial infections and disease research
  • Aquaculture disease management and microbiota
  • Viral gastroenteritis research and epidemiology
  • Virology and Viral Diseases
  • Livestock and Poultry Management

Universiti Putra Malaysia
2019-2023

Porcine circovirus type 3 (PCV3) is a newly emerging virus in the swine industry, first reported recently 2016. PCV3 assembles into 2000 bp circular genome; slightly larger than PCV1 (1758-1760 bp), PCV2 (1766-1769 bp) and PCV4 (1770 bp). Apart from being associated with porcine dermatitis nephropathy syndrome (PDNS), has been isolated pigs clinical signs of reproductive failures, myocarditis, respiratory disease complex (PRDC) neurologic disease. Given that increasingly countries including...

10.1371/journal.pone.0235832 article EN cc-by PLoS ONE 2020-07-24

This paper aims to update the molecular status of porcine circovirus 2 (PCV2) in Malaysia. Firstly, detection rate PCV2 farm and sampled pig population were reported be 83.78% (31/37 farms) 83.54% (66/79 pigs) positive for PCV2, respectively. was detected across all age groups, from fetuses, porkers sows. Co-detection PCV3 antigens also at a 28.77% (21/73). Secondly, antigen Malaysian abattoir lung samples: 18 out 19 (94.74%) samples originating clinically healthy finishers tested positive....

10.3390/ani12141849 article EN cc-by Animals 2022-07-21

Glaesserella (Haemophilus) parasuis, the etiological agent of Glässer's disease, is an economically significant pathogen commonly associated with serofibrinous polyserositis, arthritis, fibrinous bronchopneumonia and/or meningitis. This study first attempt to molecularly characterize and provide a detailed overview genetic variants G. parasuis present in Malaysia, reference its serotype, virulence-associated trimeric autotransporters (vtaA) gene outer membrane protein P2 (OmpP2) gene. The...

10.3390/pathogens12020308 article EN cc-by Pathogens 2023-02-12

Porcine circovirus 3 (PCV3) was recently reported in Malaysian commercial pig population 2020 by conventional polymerase chain reaction (PCR), revealing a molecular prevalence of 17.02% the sampled domestic population. This study aims to describe chromogenic situ hybridization (ISH) technique using digoxigenin (DIG)-labeled cloned PCV3 open reading frame 1 (ORF1) fragment DNA detect and localize antigen formalin-fixed, paraffin-embedded lung, lymphoid tissue specimens.

10.14202/vetworld.2023.1444-1450 article EN cc-by Veterinary World 2023-07-01

This paper reports the first nearly complete genome sequence of a Malaysian Porcine bocavirus (PBoV) detected in Malaysia from porcine organ sample.In Malaysia, both Human (HBoV) and PBoV have been reported, at prevalence 5.6% 90.9% respectively.Most recently, 2018, emerged as zoonosis when human case PBoV-related respiratory infection is reported child with history contact secretion.With this evidence PBoV, considering close between humans pigs swine industry, further study genetic...

10.17582/journal.aavs/2019/7.9.776.781 article EN Advances in Animal and Veterinary Sciences 2019-01-01

Abstract Over one decade since the first report, Malaysian porcine circovirus 2 (PCV2) molecular detection rates remain high at 83.78 and 83.54% for farm sampled domestic pig population levels respectively. Clinically healthy finishers also showed a rate of 94.74%. Most notably, major genotype shift from PCV2b to PCV2d was observed. PCV2 antigen detected in wild boar population, sharing significant nucleotide identity similarities with strains pigs. Porcine 3 (PCV3), which discovered not too...

10.1079/cabireviews.2023.0030 article EN CABI Reviews 2023-10-27

This protocol describes four separate PCR runs to amplify the complete genome sequence of Porcine circovirus 3 (PCV3) as overlapping segments.

10.17504/protocols.io.bdd9i296 preprint EN 2020-03-09
Coming Soon ...