Irene Assaf

ORCID: 0000-0002-2687-7658
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About
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Research Areas
  • Colorectal Cancer Treatments and Studies
  • Cancer Genomics and Diagnostics
  • Pancreatic and Hepatic Oncology Research
  • Gastric Cancer Management and Outcomes
  • Digestive system and related health
  • Colorectal Cancer Surgical Treatments
  • Helicobacter pylori-related gastroenterology studies
  • Cancer Immunotherapy and Biomarkers
  • Genetic factors in colorectal cancer
  • Cancer Diagnosis and Treatment

Institut Jules Bordet
2024

Université Libre de Bruxelles
2021-2024

Erasmus Hospital
2021

Zagazig University
2015

Immune checkpoint inhibitors and immune-related biomarkers are increasingly investigated in rectal cancer (RC). We retrospectively analysed PD-L1 expression diagnostic biopsy resection samples from RC patients treated at our centre between 2000 2020. immunostaining (22C3 clone) was evaluated according to tumour proportion (TPS), immune cell (ICS), the combined positive score (CPS). Eighty-three were included. At diagnosis, ≥1%/≥5% observed 15.4%/0%, 80.7%/37.4%, 69.2%/25.6% of based on TPS,...

10.3390/cancers16142606 article EN Cancers 2024-07-21

Background and aim:The material of this study comprises 57 gastric biopsies including paraffin blocks selected from the archives Pathology Department, Faculty medicine, Zagazig University in addition to 10 freshly randomly endoscopic were obtained Endoscopy Unit Tropical Medicine department, Medicine, hospital period 2011-2013 examine expression CDX2,MUC2 MUC6 cases chronic gastritis, metaplasia, dysplasia cancer role these markers as predictors progression gastritis carcinoma.Methods:...

10.21608/zumj.2015.4454 article EN Zagazig University Medical Journal 2015-01-01
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