Karen Geboes
A5020227571- Colorectal Cancer Treatments and Studies
- Pancreatic and Hepatic Oncology Research
- Neuroendocrine Tumor Research Advances
- Genetic factors in colorectal cancer
- Gastric Cancer Management and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Surgical Treatments
- Cancer Genomics and Diagnostics
- Lung Cancer Research Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Colorectal and Anal Carcinomas
- Microscopic Colitis
- Palliative Care and End-of-Life Issues
- Inflammatory Bowel Disease
- Esophageal Cancer Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Diet and metabolism studies
- Cancer survivorship and care
- Neuroblastoma Research and Treatments
- Colorectal Cancer Screening and Detection
- Medical Imaging Techniques and Applications
- Esophageal and GI Pathology
- Digestive system and related health
- Helicobacter pylori-related gastroenterology studies
Ghent University Hospital
2016-2025
Universitair Ziekenhuis Brussel
2010-2024
Cancer Research Institute Ghent
2021-2024
Ghent University
2019-2023
Amsterdam University Medical Centers
2022
KU Leuven
2000-2009
Universitair Ziekenhuis Leuven
1986-2009
Hôpital Universitaire Dupuytren
2004-2005
Nagoya City University
1998
Inserm
1998
No adjuvant treatment has been established for patients who remain at high risk recurrence after neoadjuvant chemoradiotherapy and surgery esophageal or gastroesophageal junction cancer.
An endoscopical and histological study was carried out in 114 patients, treated by 9curative9 resection of the terminal ileum part colon for Crohn9s disease, order to natural history recurrent disease. The recurrence rate disease patients examined within one year operation 72%. This figure did not differ significantly from that three years or 10 after surgery (79% 77% respectively). Recurrence located neoterminal at anastomosis 88% patients. Early endoscopic signs were small aphthous ulcers...
Data suggest selective internal radiotherapy (SIRT) in third-line or subsequent therapy for metastatic colorectal cancer has clinical benefit patients with liver metastases liver-dominant disease after chemotherapy. The FOXFIRE, SIRFLOX, and FOXFIRE-Global randomised studies evaluated the efficacy of combining first-line chemotherapy SIRT using yttrium-90 resin microspheres metastases. were designed combined analysis overall survival.
Background —The pathology of non-alcoholic chronic pancreatitis has not yet been sufficiently studied. Aims —To identify the major changes pancreatic tissue in patients surgically treated for pancreatitis. Patients —Pancreatectomy specimens from 12 with pancreatitis, including four autoimmune or related diseases (Sjögren’s syndrome, primary sclerosing cholangitis, ulcerative colitis, and Crohn’s disease), were reviewed. Methods —Morphological studied histologically immunohistochemically (to...
Background. Diarrhea is the most frequently reported adverse event in mycophenolate mofetil (MMF)-treated transplant patients. The aim of this study was to explore gastrointestinal tract MMF-treated renal recipients with persistent afebrile diarrhea characterize its nature and etiology. Methods. Renal (daily fecal output >200 g) were prospectively investigated for infections, morphologic, functional (gastrointestinal motility intestinal absorptive capacity) integrity tract; 26 patients met...
The purpose of this study was to assess the role dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and (18)F-fluorodeoxyglucose positron emission tomography computed (FDG-PET/CT) for evaluation response chemotherapy bevacizumab prediction progression-free survival (PFS) in patients with metastatic colorectal cancer (mCRC) potentially resectable liver lesions.A total 19 mCRC were treated FOLFOX/FOLFIRI followed by surgery. Dynamic FDG-PET/CT performed before treatment after cycle...
The prognostic value of body composition in cancer patients has been widely studied during the last decade. main finding these studies is that sarcopenia, or skeletal muscle depletion, assessed by CT imaging correlates with a reduced overall survival (OS). By contrast, fat mass remains ill-defined. This study aims to analyze influence including both and adipose tissue on OS homogeneous population advanced colorectal (CRC) patients.Among 235 chemorefractory CRC included SoMore RegARd-C...
<h3>Background</h3> Enadenotucirev is a chimeric adenovirus with demonstrated preclinical tumor-selective cytotoxicity and short half-life. Further clinical mechanism of action data showed that enadenotucirev can gain access to replicate within different types epithelial tumors. This phase 1 dose escalation study assessed intravenous (IV) establish the maximum tolerated (MTD) subsequently identify suitable schedule for repeated cycles. <h3>Methods</h3> Sixty-one patients advanced tumors...
<sup>18</sup>F-labeled somatostatin analogs (SSAs) could represent a valid alternative to the current gold standard, <sup>68</sup>Ga-labeled SSAs, for receptor imaging in patients with neuroendocrine tumors (NETs), given their logistic advantages. Recently, <sup>18</sup>F-AlF-NOTA-octreotide (<sup>18</sup>F-AlF-OC) has emerged as promising candidate, but thorough comparison <sup>68</sup>Ga-DOTA-SSA large patient groups is needed. This prospective, multicenter trial aims demonstrate...
Recently, the number of prehabilitation trials has increased significantly. The identification key research priorities is vital in guiding future directions. Thus, aim this collaborative study was to define for patients undergoing cancer surgery.The Delphi methodology implemented over three rounds surveys distributed experts from across multiple specialties, tumour streams and countries via a secure online platform. In first round, participants were asked provide baseline demographics...
Abstract Human papillomaviruses (HPV) are associated with benign lesions and show specificity towards the location or tissues that they infect. HPVs responsible for warts. Among more than 60 different HPV types known to occur in humans, a strong association has been found between 16 18 cervical cancer, such an is also suspected 31, 33, 35, 45, 51, 52, 56. We describe effects of (S)‐1‐(3‐hydroxy‐2‐phosphonyl‐methoxypropy Dcytosine (HPMPC), following local intratumoral injection, 69‐year‐old...
Studies attempting to evaluate protein assimilation in humans have hitherto relied on either ileostomy subjects or intubation techniques. The availability of stable isotope-labeled allowed us determine the amount and fate dietary escaping digestion absorption small intestine healthy volunteers using noninvasive tracer Ten were studied once after ingestion a cooked test meal, consisting 25 g 13 C-, 15 N-, 2 H-labeled egg protein, same but raw meal. Amounts 5.73% 35.10% ( P < 0.005)...