A5089568833- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Lung Cancer Diagnosis and Treatment
- Simulation-Based Education in Healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Surgical Simulation and Training
- Bariatric Surgery and Outcomes
- Body Contouring and Surgery
- Diet and metabolism studies
- Epigenetics and DNA Methylation
- Diversity and Career in Medicine
- Acute Kidney Injury Research
- Hemodynamic Monitoring and Therapy
- Cerebrovascular and Carotid Artery Diseases
- Dysphagia Assessment and Management
- Enhanced Recovery After Surgery
- Airway Management and Intubation Techniques
- Multiple and Secondary Primary Cancers
- Radiology practices and education
- Healthcare professionals’ stress and burnout
- COVID-19 and healthcare impacts
- Gastroesophageal reflux and treatments
- Cancer Genomics and Diagnostics
- Innovations in Medical Education
Ghent University Hospital
2010-2024
Amsterdam University Medical Centers
2022
University of Amsterdam
2022
AZ Sint-Jan
2012-2014
Background: Surgical resection, for the most part after neoadjuvant therapy, remains primary curative option esophageal cancer, yet cancer recurrence poses a significant challenge to patient outcomes. Previous literature has shown that various anesthetic drugs could potentially influence oncological outcomes surgical resection of malignant tumors. This retrospective cohort study investigates patient-controlled epidural analgesia (PCEA) compared intravenous (PCIA) on following minimally...
Approximately 10–12% of patients with oesophageal or gastric cancer (OGC) present oligometastatic disease at diagnosis. It remains unclear if there is a role for radical surgery in these patients. We aimed to assess the outcomes OGC who underwent simultaneous treatment primary tumour and synchronous liver metastases. Patients surgical between 2008 2020 up five metastases aiming complete removal ablation (i.e., no residual tumour) were identified from four institutional databases. The outcome...
SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. This is a cross-sectional study reported in compliance with CHERRIES guidelines conducted through an online platform from June 14th July 15th, 2020. The primary outcome was burden burnout during indicated by validated Shirom-Melamed Burnout Measure. Nine hundred fifty-four completed survey. median length practice 10...
Anastomotic Leakage (AL) remains the main cause of post-esophagectomy morbidity and mortality. Early detection can avoid sepsis reduce This study evaluates diagnostic accuracy NUn-score its components as early detectors AL. single centre observational cohort included all esophagectomies from 2010-2020. C-reactive Protein (CRP), Albumin (Alb) White cell count (WCC) were analyzed Nun-scores calculated. Area under curves (AUC) used to assess their predictive accuracy. Seventy-four 668 patients...
Anastomotic leakage (AL) remains the main cause of post-esophagectomy morbidity and mortality. Early detection can avoid sepsis reduce This study evaluates diagnostic accuracy Nun score its components as early detectors AL. single-center observational cohort included all esophagectomies from 2010 to 2020. C-reactive protein (CRP), albumin (Alb), white cell count (WCC) were analyzed NUn scores calculated. The area under curve statistic (AUC) was used assess their predictive accuracy. A total...
Introduction: Surgery remains essential in the curative treatment of esophageal cancer (EC), but it is known for its high morbidity and impaired health-related QoL. Minimally invasive esophagectomy (MIE) was introduced to reduce surgical trauma improve Methods: This cross-sectional study aimed evaluate long-term HRQoL after MIE comparison with general population. assessment based on three questionnaires: European Organisation Research Treatment Cancer (EORTC) Core 30 (QLQ-C30, version 3),...
Introduction Assessments require sufficient validity evidence before their use. The Assessment for Competence in Chest Tube Insertion (ACTION) tool evaluates proficiency chest tube insertion (CTI), combining a rating scale and an error checklist. aim of this study was to collect the ACTION on porcine rib model according Messick framework. Methods A model, consisting hemithorax that placed wooden frame, used as simulator. Participants were recruited from departments surgery, pulmonology,...
Abstract Background Approximately 10-12% of patients with oesophageal and gastric cancer (OGC) present oli-gometastatic metastases at diagnosis. It remains unclear if there is a role for radical surgery in these patients. We aimed to assess the outcomes OGC who underwent simultaneous treatment primary tumour synchronous liver metastases. Methods Patients surgical between 2008 2020 up five aiming complete removal or ablation (i.e. no residual tumour) were identified from four institutional...
Background: The decision for volume expansion or fluid removal during surgery is often based on urinary output. use of intravenous furosemide can reverse oliguria but may harm renal function. aim this study to explore the occurrence postoperative acute kidney injury (AKI) in patients receiving compared not furosemide. Methods: Single centre cohort study. Adults scheduled elective minimal invasive esophagectomy from October 2015 until December 2021 were included. primary outcome was AKI...
Introduction Chest tube insertions (CTIs) have a high complication rate, prompting the training of technical skills in simulated settings. However, assessment tools require validity evidence prior to their implementation. This study aimed collect for CTI on Thiel-embalmed human bodies. Methods Invitations were sent residents and staff from departments surgery, pulmonology, emergency medicine. Participants familiarized with Thiel body supplied equipment. Standardized clinical context...
Abstract Background Studies have shown minimally invasive esophagectomy (MIE) to be a feasible surgical technique in treating esophageal carcinoma. Postoperative complications been extensively reviewed, but literature focusing on intraoperative is limited. The main objective of this study was report major and 90-day mortality during MIE for cancer. Methods Data were collected retrospectively from 10 European surgery centers. All intention-to-treat, laparoscopic/thoracoscopic esophagectomies...
Abstract Studies have shown minimally invasive esophagectomy (MIE) to be a feasible surgical technique in treating esophageal carcinoma, with equal oncological results as open surgery. The number of MIEs Europe are increasing. Postoperative complications been recently reviewed by multicenter study that benchmarked MIE outcomes. There no studies, date, regarding major intraoperative during and their effect on patient survival. Data was gathered retrospectively from 10 European centers minimum...