A5055119700- Gut microbiota and health
- Gout, Hyperuricemia, Uric Acid
- Mycotoxins in Agriculture and Food
- Helicobacter pylori-related gastroenterology studies
- Physiological and biochemical adaptations
- Pharmacological Effects of Natural Compounds
- Circadian rhythm and melatonin
- Food composition and properties
- Plant and fungal interactions
- Biochemical and Molecular Research
- Alcohol Consumption and Health Effects
- Clostridium difficile and Clostridium perfringens research
- Photoreceptor and optogenetics research
- Spaceflight effects on biology
- Metabolism and Genetic Disorders
- Fungal and yeast genetics research
- Genomics, phytochemicals, and oxidative stress
- Probiotics and Fermented Foods
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2023-2024
Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)
2023-2024
Sun Yat-sen University
2024
South China Agricultural University
2020-2022
Key Laboratory of Guangdong Province
2022
Dietary fiber (DF) improves gastrointestinal health and has important associations with the alleviation of intestinal diseases metabolic syndrome. However, due to DFs complex characteristics, such as solubility, viscosity, fermentability, mechanism in these was not consistent. As an herbivore, goose a prominent digestive ability DF. Therefore, we choose low, medium, high viscosity (respectively resistant starch-3 []RS], inulin [INU], β-glucan [GLU]) Magang diet treatment for 4 wk,...
Abstract Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted relationship between the gut microbiota and gout, whether could ameliorate HUA-associated systemic metabolism remains unclear. In this study, we constructed novel model of HUA in geese investigated mechanism which Lactobacillus rhamnosus GG (LGG) beneficial effects on HUA. The administration antibiotics fecal transplantation (FMT) experiments were used goose model....
Melatonin (MEL) shows an anti-inflammatory effect and regulates intestinal microbiota communities in animals humans; Ochratoxin A (OTA) induces liver inflammation through microbiota. However, it remains to know whether MEL alleviates the induced by OTA. In this study, reversed various adverse effects recovered swarming motility of microbiota, decreased accumulation lipopolysaccharide (LPS), enhanced tight junction proteins jejunum cecum segments; ultimately alleviated OTA-induced ducks. is...
The gut microbiota is implicated in the pathogenesis of hyperuricemia (HUA) and gout. However, it remains unclear whether probiotics residing host gut, such as Lactobacillus, can prevent HUA development. Herein, we isolated Lactobacillus plantarum SQ001 from cecum geese conducted vitro assays on uric acid (UA) nucleoside co-culture. Metabolomics genome-wide analyses, revealed that this strain may promote uptake hydrolysis through its hydrolase gene. functional role iunH gene was confirmed...
Abstract Background Ochratoxin A (OTA) is a mycotoxin widely present in raw food and feed materials mainly produced by Aspergillus ochraceus Penicillium verrucosum . Our previous study showed that OTA principally induces liver inflammation causing intestinal flora disorder, especially Bacteroides plebeius ( B. ) overgrowth. However, whether or alteration leads to abnormal tryptophan-related metabolism the intestine largely unknown. This aimed elucidate metabolic changes induced pathway...
Gout is a disease involving abnormal purine metabolism that widespread in mammals and birds. Goose especially susceptible for gout early stage. However, few studies investigated the ontogenetic pattern of goslings with metabolic abnormality. Our were conducted to investigate whether persistent abnormality would lead aggravation visceral inflammation intestinal microbiota dysbiosis goose. A total 132 1-day-old Magang geese randomly divided into six replicates fed high-calcium protein...
Graphical Abstract Blue light improves lipid metabolism by altering and gut microbes.
Abstract Gut microbiota has been considered to be associated with the development of hyperuricemia (HUA) and gout. Some prebiotics from different sources had potential alleviation function in HUA. However, whether host-derived probiotics, like Lactobacillus, gut HUA animals could prevent is still uncertain. In this study, we established a geese model isolated Lactobacillus plantarum strain, SQ001, cecum geese. Nucleoside co-culture metabolomics analyses revealed that L. SQ001 involved...
Abstract Background: The gut microbiota plays a critical role in metabolism and growth of piglets, was modifiable by dietary tryptophan (Trp) previous study. However, no studies focused on the investigation whether additional Trp supplementation would modulate composition ileum cecum piglets challenged lipopolysaccharide (LPS). We conducted to investigate could alleviate dysbacteriosis after with LPS. Methods: A total 40 28 days old male weaning were randomly allotted five groups, include...