A5036348552- Hormonal and reproductive studies
- Sperm and Testicular Function
- Fatty Acid Research and Health
- Ovarian function and disorders
- Wnt/β-catenin signaling in development and cancer
- Cancer-related molecular mechanisms research
- Cancer Cells and Metastasis
- Nutrition, Genetics, and Disease
- Reproductive Biology and Fertility
- Phytoestrogen effects and research
Universidad Autónoma Metropolitana
2022-2025
Infertility is increasingly recognized as being closely linked to obesity in humans. The successful production of fertile spermatozoa requires adequate spermatogenesis within the testis and proper maturation through epididymis. This study aimed evaluate impact body adiposity on male fertility, focusing sperm parameters, epididymal maturation, capacitation Wistar rats. Male rats were randomized into three dietary groups over four weeks: a control group receiving less than 4% lard, regular...
Obesity is a condition that has been linked to male infertility. The current hypothesis regarding the cause of infertility sperm are highly sensitive reactive oxygen species (ROS) during spermatogenesis in testes and transit through epididymides, so increase ROS brought on by obesity could oxidative stress. aim this study was evaluate whether activity enzymes catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPX) capable counteracting stress sperm. Wistar rat used as an...
The epithelial-to-mesenchymal transition (EMT) is the main event that favors cell migration and metastasis in breast cancer. Previously, we demonstrated 1 nM estradiol (E2) promotes EMT, induced by c-Src kinase, causing changes localization of proteins compose tight junction (TJ) adherens (AJ).The present work highlights central role initiation metastasis, E2, through increasing ability MCF-7 T47-D cells, which express estrogen receptor alpha (ERα), to migrate invade before they become...