- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Airway Management and Intubation Techniques
- Anesthesia and Pain Management
- Hemodynamic Monitoring and Therapy
- Respiratory Support and Mechanisms
- Tracheal and airway disorders
- Cancer, Stress, Anesthesia, and Immune Response
- Veterinary Pharmacology and Anesthesia
- Thermal Regulation in Medicine
- Cardiac Arrest and Resuscitation
- Renal function and acid-base balance
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Dental Anxiety and Anesthesia Techniques
- Intensive Care Unit Cognitive Disorders
- Thermoregulation and physiological responses
- Voice and Speech Disorders
- Nausea and vomiting management
- Blood Pressure and Hypertension Studies
- Cardiac Ischemia and Reperfusion
- Foreign Body Medical Cases
- Intraoperative Neuromonitoring and Anesthetic Effects
- Electrolyte and hormonal disorders
- Healthcare Regulation
Universidade Estadual Paulista (Unesp)
2015-2024
Surgical Specialties (United States)
2024
Centro Universitário de João Pessoa
2020
Universidade de São Paulo
2000-2017
Fundação de Apoio à Universidade Federal de São Paulo
1997-2014
Tufts University
2014
Faculdade de Medicina de São José do Rio Preto
2008
European Society of Anaesthesiology
2006
Sociedade Brasileira de Anestesiologia
2002-2005
São Paulo State Technological College
1998
Little information on the factors influencing intraoperative cardiac arrest and its outcomes in trauma patients is available. This survey evaluated associated of a Brazilian teaching hospital between 1996 2009.Cardiac during anesthesia was identified from an database. The data collected included patient demographics, ASA physical status classification, provider information, type surgery, surgical areas outcome. All arrests deaths were reviewed grouped by also analyzed as totally...
In 2006, a previous study at our institution reported high perioperative and anesthesia-related mortality rates of 21.97 1.12 per 10,000 anesthetics, respectively. Since then, changes in surgical practices may have decreased these rates. However, the actual Brazil remains unknown. The aimed to reexamine one Brazilian tertiary teaching hospital.In this observational study, deaths occurring operation room postanesthesia care unit between April 2005 December 2012 were identified from an...
CONTEXT: High compliance endotracheal tubes cuffs are used to prevent gas leak and also pulmonary aspiration in mechanically ventilated patients. However, the use of usual cuff inflation volumes may cause tracheal damage. OBJECTIVE: We tested hypothesis that tube pressures routinely high (above 40 cmH2O) Post Anesthesia Care Unit (PACU) or Intensive Units (ICU). DESIGN: Cross-sectional study. SETTING: anesthesia care unit intensive unit. PARTICIPANTS: measured pressure 85 adult patients, as...
The incidence of perioperative cardiac arrest and mortality in children is higher than adults. This survey evaluated the incidence, causes, outcome arrests a pediatric surgical population tertiary teaching hospital between 1996 2004.The during anesthesia was identified from an database. During study period, 15,253 anesthetics were performed children. Data collected included patient demographics, procedures (elective, urgent, or emergency), ASA physical status classification, provider...
To investigate the effects of occupational exposure to waste anesthetic gases on genetic material and antioxidant status in professionals during their medical residency.The study group consisted 15 residents from Anesthesiology Surgery areas, both genders, mainly exposed isoflurane a lesser degree sevoflurane nitrous oxide; control young adults not anesthetics. Blood samples were drawn residency (eight, 16 22 months gases). DNA damage was evaluated by comet assay, defense assessed total...
Little information is known about factors that influence perioperative and anesthesia-related cardiac arrest (CA) in older patients. This study evaluated the incidence, causes outcome of intraoperative CA patients a Brazilian teaching hospital between 1996 2010.During study, received 18,367 anesthetics. Data collected included patient characteristics, surgical procedures, American Society Anesthesiologists (ASA) physical status, anesthesia type, medical specialty team outcome. All CAs were...
OBJETIVO: O objetivo deste estudo foi avaliar as características clínicas da anestesia peridural realizada com ropivacaína associada à dexmedetomidina. MÉTODOS: Quarenta pacientes submetidos correção cirúrgica de hérnia inguinal ou varizes membros inferiores sob participaram estudo. Os foram divididos em: Grupo Controle (n = 20), 0,75%, 20 ml (150 mg); e Dexmedetomidina mg), mais dexmedetomidina, 1 µg.kg-1. As variáveis estudadas foram: tempo latência do bloqueio sensitivo, dermátomo máximo...
Recent studies have demonstrated the genotoxicity of anesthetics in patients who undergone surgery and personnel are occupationally exposed to anesthetics. However, these findings controversial. Herein, we used comet assay (single-cell gel electrophoresis) investigate genotoxic effects two volatile compounds [isoflurane (ISF) sevoflurane (SVF)] that inhalation anesthesia, one intravenous (iv) anesthetic compound [propofol (PF)]. The groups consisted 45 underwent minimally invasive lasted at...
Isoflurane is a volatile halogenated anesthetic used especially for anesthesia maintenance whereas propofol venous utilized induction and maintenance, reportedly an antioxidant. However, there are still controversies related to isoflurane-induced oxidative stress it remains unanswered whether the antioxidant effects occur in patients under anesthesia. Taking into account importance of better understanding role anesthetics on anesthetized patients, present study was designed evaluate general...
Summary Our aim was to compare peri‐operative core temperatures and the incidence of hypothermia in obese non‐obese women with active forced‐air warming. Twenty female patients scheduled for abdominal surgery were allocated two groups according body mass index. Ten (30.0–34.9 kg.m −2 ) 10 (18.5–24.9 received warming on their lower limbs. At end surgery, mean (SD) 36.7 (0.5) °C group 36.0 (0.6) (p < 0.001). Only there a significant decrease intra‐operative temperature values The incidences...
The waste anesthetic gases (WAGs) present in the ambient air of operating rooms (OR), are associated with various occupational hazards. This paper intends to discuss exposure WAGs and its impact on exposed professionals, emphasis genetic damage oxidative stress. Despite emergence safer inhaled anesthetics, remains a current concern. Factors related techniques anesthesia workstations, addition absence scavenging system OR, contribute pollution. In order minimize health risks several countries...
CONTEXT AND OBJECTIVE: High intracuff pressure in endotracheal tubes (ETs) may cause tracheal lesions. The aim of this study was to evaluate the effectiveness and safety tube cuffs filled with air or alkalinized lidocaine. DESIGN SETTING: This a prospective clinical at Department Anesthesiology, Faculdade de Medicina Botucatu, Universidade Estadual Paulista. METHODS: Among 50 patients, ET cuff pressures were recorded before, 30, 60, 90 120 minutes after starting upon ending nitrous oxide...
There are numerous studies reporting on the effects of inhalation anaesthesia in cells exposed individuals but not much is known about ability isoflurane (ISF) to induce oxidative DNA damage. However, surgery often associated with a temporary perioperative immunological alteration, and some volatile anaesthetics seem contribute transient lymphocytopenia after surgery. We conducted study evaluate possible genotoxic effect, including damage, apoptosis peripheral lymphocytes 20 patients...
A previous survey performed in our institution demonstrated perioperative pediatric cardiac arrest and mortality rates of 22.9 9.8 per 10,000 anesthetics, respectively, an anesthesia-related rate 4.58 anesthetics. Changes practices (i.e., safer anesthesia techniques change population) may have altered rates. The aim this investigation was to reexamine the rates, causes, outcomes a Brazilian institution.Observational study.Tertiary teaching hospital.Children less than 18 years old, who were...
This cross-sectional study analyzed the impact of occupational waste anesthetic gases on genetic material, oxidative stress, and inflammation status in young physicians exposed to inhalational anesthetics at end their medical residency. Concentrations were measured operating rooms assess pollution. The group comprised individuals occupationally anesthetics, while control without exposure. We quantified DNA damage; instability (micronucleus-MN); protein, lipid, oxidation; antioxidant...
Hemodynamic and global oxygen transport variables have failed to reflect splanchnic hypoperfusion, resulting in a failure recognize inadequately treated hemorrhagic shock. Volemic expansion after fluid resuscitation is essential improve regional We hypothesized that, contrast conventional plasma expanders, the smaller volemic from 7.5 NaCl/6% hydroxyethyl starch (HHES) solution administration shock may provide lesser systemic delivery gastric perfusion. used hemorrhaged dogs compare...