A5083416064- Phytochemical compounds biological activities
- Alkaloids: synthesis and pharmacology
- Natural product bioactivities and synthesis
- Traditional and Medicinal Uses of Annonaceae
- Phytochemistry and Biological Activities
- Phytochemistry and Bioactivity Studies
- Essential Oils and Antimicrobial Activity
- Chemical synthesis and alkaloids
- Marine Sponges and Natural Products
- Plant biochemistry and biosynthesis
- Plant tissue culture and regeneration
- Insect Pest Control Strategies
- Phytochemistry Medicinal Plant Applications
- Mycorrhizal Fungi and Plant Interactions
- Banana Cultivation and Research
- Phytochemistry and Bioactive Compounds
- Growth and nutrition in plants
- Bioactive Compounds and Antitumor Agents
- Plant chemical constituents analysis
- Fungal Biology and Applications
- Sesquiterpenes and Asteraceae Studies
- Phytochemicals and Antioxidant Activities
- Phytochemical Studies and Bioactivities
- Synthesis of Indole Derivatives
- Plant Diversity and Evolution
State University of Norte Fluminense
2016-2025
Universidade do Porto
2025
Prefeitura Municipal de Campos dos Goytacazes
2013-2024
Instituto Federal Fluminense
2019
Universidade Federal Rural do Rio de Janeiro
2018
Northern State University
2010-2014
Universidade Federal de Viçosa
2009
Universidade Federal do Ceará
2007
Natura (Brazil)
1999-2005
Universidade Federal do Rio de Janeiro
1999
How to make bioactive alkaloids Vinblastine and vincristine are important, expensive anticancer agents that produced by dimerization of the plant-derived catharanthine vindoline. The enzymes transform tabersonine into vindoline known; however, mechanism which scaffolds generated has been a mystery. Caputi et al. now describe biosynthetic genes corresponding responsible. This resolves long-standing question how plant alkaloid synthesized, is important not only for vinblastine biosynthesis,...
The aroma and fragrance industry is a billion-dollar world market which grows annually. Essential oils comprise the majority of compounds used by these industries. These sets metabolites are formed mainly monoterpenes, products plants' secondary metabolism. Biosynthesized from mevalonate methylerythitol phosphate, essential oil production depends not only on genetic factors developmental stage plants, but also environmental could result in biochemical physiological alterations plants...
O objetivo deste trabalho foi avaliar os efeitos de diferentes espécies fungos micorrízicos arbusculares (FMA) na produção e qualidade óleos essenciais Mentha arvensis L., cultivada com doses fósforo. realizado em casa vegetação o delineamento estatístico utilizado blocos ao acaso 20 tratamentos, constituídos pela combinação cinco tratamentos microbiológicos (Glomus clarum Nicolson & Schenck, Glomus etunicatum Becker Gerdemann, Gigaspora margarita Hall, Acaulospora scrobiculata Trappe...
This study identified two phenolic compounds in Schinus terebinthifolius Raddi fruits: naringenin (first report this species) and gallic acid. Their structures were elucidated by nuclear magnetic resonance (NMR) data (¹H-, 13C-NMR) a high-performance liquid chromatography (HPLC) technique. A high content of phenolics (659.21 mg acid equivalents/g sample-Folin-Ciocalteau method) total flavonoids (140.69 rutin sample-aluminum chloride quantified S. terebinthifolius, as well antioxidant...
Jambu, a plant native to the Amazon, is rich in essential oils, particularly spilanthols and phytols. Although hydroponic cultivation of this vegetable practiced, process remains relatively understudied. In context, study aimed assess influence electrical conductivity nutrient solutions on jambu production. Greenhouse experiments were conducted at Universidade Estadual do Norte Fluminense (UENF), Brazil, employing randomized block design encompassing six blocks comprising Hoagland Arnon with...
The fragmentation of four deprotonated plumeran indole (PIAs), namely alkaloids aspidospermidine (1), demethoxypalosine (2), aspidocarpine (3), and aspidolimine (4) (PIA), previously isolated from Aspidosperma spruceanum has been investigated by electrospray ionization tandem mass spectrometry (ESI-MS/MS) in the negative ion mode. pathways have established on basis accurate data. Our results demonstrated that main product ions 1-4 result remote hydrogen rearrangements. most abundant spectrum...
This study evaluates the applicability of Demirjian and Willems’ methods for age estimation in Portuguese children aged 6–9 years based on orthopantomographs (OPGs). The main objective was to compare precision both estimating chronological (CA). analyzed 160 OPGs, equally distributed by sex, dental (DA) calculated twice, using methodologies. findings reveal that Demirjian’s method consistently overestimated an average 1.47 males 1.45 females. Similarly, Willems also but a lesser extent, with...
Background/Objectives: Andiroba oil, extracted from Carapa guianensis seeds, possesses therapeutic properties including anti-inflammatory and wound healing effects. This study aimed to develop characterize a nanoemulsion formulation containing andiroba oil (NeAnd) evaluate its cytotoxicity potential in vitro. Methods: The was evaluated for acidity, antioxidant activity, fatty acid composition. NeAnd produced by ultrasonication characterized using FTIR (Fourier transform infrared...
The fragmentation of four deprotonated plumeran indole (PIAs), namely alkaloids aspidospermidine (1), demethoxypalosine (2), aspidocarpine (3), and aspidolimine (4) (PIA), previously isolated from Aspidosperma spruceanum has been investigated by electrospray ionization tandem mass spectrometry (ESI-MS/MS) in the negative ion mode. pathways have established on basis accurate data. Our results demonstrated that main product ions 1-4 result remote hydrogen rearrangements. most abundant spectrum...
This work evaluated the antiproliferative potential of Eugenia brasiliensis leaf extracts against HeLa cervical cancer cell line. The were prepared by maceration using hexane (EBH), dichloromethane (EBD), and ethyl acetate (EBAE), they for their through an MTT assay in culture (HeLa line) a non-cancer line (NIH-3T3). EBH, EBD, EBAE cytotoxic cells, with IC50 =97.59 μg/mL, = 31.03 57.67 respectively. EBD inhibited migration altered cycle. Eight compounds tentatively assigned to E....
Agave sisalana (sisal) is known worldwide as a source of hard fibers, and Brazil the largest producer sisal. Nonetheless, process removing fibers sisal leaf generates 95% waste. In this study, we applied chemical sequential steps (hydrothermal extraction, precipitation, liquid-liquid crystallization, SiO2 Sephadex LH 20 column chromatography) to obtain pectin, mannitol, succinic acid, kaempferol mixture saponins raw chemicals from biomass. The structural identification these compounds was...
According to the literature data on chemical composition of Trichilia genus performed in this work, it can be concluded that 334 different compounds were isolated and identified, distributed monoterpenes, sesquiterpenes, diterpenes, triterpenes, steroids, limonoids, coumarins, flavonoids, lignans, phenolic acids, amino acids lactones. Together with structures compound, from botanical classification pharmaco-logical results extracts pure also described. The derived terpenes pathway more...
The aim of this work was to assess the effects inoculation with arbuscular mycorrhizal fungi (AMF) and P doses on quality chili pepper fruits (Capsicum annuum var. annuum) plants grown under greenhouse conditions. Fruit production, size (total soluble solids, titratable acidity, ascorbic acid, mineral composition capsaicinoids content) were assessed. Inoculated had increased number per plant compared non-inoculated plants. best response obtained at low soil concentrations. a good dependency....
SUMMARY The benefits of mycorrhizal inoculation on growth, yield and nutrition plants are well documented. However, mycorrhiza use in pepper sweet crops ( Capsicum spp.) is still rarely exploited compared to other economic importance. current paper reviews the main aspects association between arbuscular (AM) fungi pepper. It includes topics about effects AM nutrition, growth spp., paying particular attention fungi–pathogen interactions, responses some environmental stresses, as biochemical...
Aqueous suspension of ethanol extracts Derris (Lonchocarpus) urucu (Leguminosae), collected in the state Amazonas, Brazil, were tested for larvicidal activity against mosquito Aedes aegypti (Diptera:Culicidae). The aim this study was to observe alterations peritrophic matrix Ae. larvae treated with an aqueous D. extract. Different concentrations root extract fourth instar larvae. One hundred percent mortality observed at 150 µg/ml (LC50 17.6 µg/ml) 24 h following treatment. In response...
Embora sejam conhecidas principalmente como fonte de madeira nobre para aplicação na construção móveis, as espécies do gênero Aspidosperma apresentam muitos estudos área da fitoquímica e poucos farmacologia. As são largamente aplicadas por populares potenciais agentes antimaláricos, no tratamento leishmaniose, inflamações útero ovário, anticonceptiva, em diabetes problemas estomacais, contra câncer, febre reumatismo. Do ponto vista químico, a grande maioria das constituintes já foi submetida...