A5045951341- Vitamin D Research Studies
- Parathyroid Disorders and Treatments
- Pituitary Gland Disorders and Treatments
- Bone health and osteoporosis research
- Electrolyte and hormonal disorders
- Pharmacological Effects and Toxicity Studies
- Vitamin C and Antioxidants Research
- Potassium and Related Disorders
- Diet, Metabolism, and Disease
- Blood Pressure and Hypertension Studies
- Metabolism and Genetic Disorders
- Stress Responses and Cortisol
- Diabetes and associated disorders
- Bone health and treatments
- Neuropeptides and Animal Physiology
- Myasthenia Gravis and Thymoma
- Biomedical and Chemical Research
- Fatty Acid Research and Health
- Hormonal Regulation and Hypertension
- Security, Politics, and Digital Transformation
- Bariatric Surgery and Outcomes
- Hormonal and reproductive studies
- Hypothalamic control of reproductive hormones
- Growth Hormone and Insulin-like Growth Factors
- Eating Disorders and Behaviors
Endocrinology Research Center
2020-2024
Library of the Russian Academy of Sciences
2019
Faculdades Guarulhos
2019
Peoples' Friendship University of Russia
2015
Sechenov University
2015
Novosibirsk Scientific Research Institute of Traumatology and Orthopedics. Ya.L. Tsivyan
2012
In this prospective controlled study, we examined 25 adults with adequately (HbA1c level < 8.0%) type 1 diabetes mellitus (T1DM) and 49 conditionally healthy adults, intending to reveal the diversity of vitamin D metabolism in setting cholecalciferol intake at a therapeutic dose. All patients received single dose (150,000 IU) aqueous solution orally. Laboratory assessments including serum metabolites (25(OH)D3, 25(OH)D2, 1,25(OH)2D3, 3-epi-25(OH)D3 24,25(OH)2D3), free 25(OH)D, D-binding...
Vitamin D (25-hydroxyvitamin [25(ОН)D]) deficiency (<20 ng/mL) and insufficiency (20-29 are common in primary hyperparathyroidism (PHPT), but data regarding the vitamin metabolism this population is limited.The aim of study to estimate metabolites their relationship with main parameters phosphorus-calcium patients PHPT at baseline on background a single dose cholecalciferol 150,000 IU.A single-center interventional, dynamic, prospective, comparative has been carried out. The included 54...
Only a few studies evaluating the metabolism of vitamin D in patients with hypoparathyroidism (HypoPT) have been performed thus far, and, particular, they mainly investigated process activation (specifically, 1α-hydroxylation). This study, therefore, aimed to evaluate extended spectrum metabolites HypoPT compared healthy individuals. We examined 38 adult chronic comparison adults. The assessment included biochemical parameters (total calcium, albumin, phosphorus, creatinine, and magnesium),...
In this study we aimed to assess vitamin D metabolism in patients with Cushing’s disease (CD) compared healthy individuals the setting of bolus cholecalciferol treatment. The group included 30 adults active CD and control apparently similar age, sex BMI. All participants received a single dose (150,000 IU) aqueous solution orally. Laboratory assessments including serum metabolites (25(OH)D3, 25(OH)D2, 1,25(OH)2D3, 3-epi-25(OH)D3 24,25(OH)2D3), free 25(OH)D, D-binding protein (DBP)...
Vitamin D-binding protein (DBP) was discovered more than half a century ago as polymorphic serum and is currently characterized by variety of physiological properties. First all, DBP carries the bulk vitamin D metabolites circulating in bloodstream, while albumin second most important transport protein, especially patients with low concentration serum. Since it that only 12% total have occupied steroid binding sites, vigorous study other potential biological roles initiated: actin...
Diabetic nephropathy (DN) is a specific kidney involvement in diabetes mellitus (DM), caused by hemodynamic and metabolic factors. In the kidneys takes place an important step metabolism of vitamin D — 1α-hydroxylation, which results formation its biologically active form. Reduced number functioning nephrons DN leads to impaired metabolism, contributing development complications. this review, we have focused detail on both normal features chronic disease (CKD). most common cause CKD and, as...
A commonly used method for determining vitamin D sufficiency is the suppression of excess PTH secretion. Conventionally, main circulating metabolite 25(OH)D this assessment, however, cut-off data parameter vary widely in literature. The role other metabolites as markers status actively debated. aim our study was to assess relationship between PTH, age and parameters characterizing status, both "classical" – 25(OH)D3, "non-classical" 24,25(OH)2D3 25(OH)D3/24,25(OH)2D3 (vitamin ratio, VMR)....
Background: Disorders of water and electrolyte balance, hyper- hyponatremia, are common postoperative complications transsphenoidal neurosurgical interventions found in up to 30–40% cases. At the same time, delayed hyponatremia is main cause repeated hospitalizations patients, risk factors/pathogenetic mechanisms responsible for development have not been fully investigated. Aim: To determine frequency water-electrolyte disturbances identify predictors dysnatriemia states patients after...
Background: findings from the previously conducted studies indicate altered regulatory mechanisms of calcium and vitamin D metabolism in obese patients a role for bariatric surgery regulating metabolism; however, available data is controversial does not provide an adequate understanding subject. Methods: we evaluated serum parameters mineral (vitamin metabolites (25(OH)D3, 25(OH)D2, 1,25(OH)2D3, 3-epi-25(OH)D3, 24,25(OH)2D3), D-binding protein (DBP), free 25(OH)D, fibroblast growth factor 23...
BACKGROUND: The prevalence of dysnatremia varies widely (from 1 to 63%), and depends on comorbidities, the effects more than 18 hormones hormone-like substances, which confirms importance maintaining blood sodium levels in tight physiologic range makes it possible consider its deviations as an endocrine pathology. Both hypo- hypernatraemia are associated with a multiple increase mortality, risk fractures, gross balance disturbances. At same time, clinical manifestations not specific, reflect...
ASBMR 2022 Annual Meeting and Vitamin D Workshop — the key international events in field of metabolic diseases skeleton pathology mineral metabolism were held September 2022. During conferences results latest research presented, promising areas further discussed, as well debates author’s sessions on controversial issues held. The article provides a brief overview events.
Abstract Disclosure: A. Zhukov: Grant Recipient; Self; Russian Science Foundation (project 19-15-00243-P). Povaliaeva: Z. Abilov: L. Usoltseva: None. D. Trukhina: E. Pigarova: Rozhinskaya: Objective: to evaluate the parameters of vitamin D metabolism and calcium phosphate homeostasis in patients undergoing bariatric surgery. Materials Methods: The study included 10 without chronic kidney disease mineral disorders who underwent laparoscopic gastric bypass surgery for obesity. After surgery,...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
The Kazan campaign of 1552 became the one most important events Ivan Terrible’s foreign policy and has repeatedly attracted attention researchers. historical tradition study this counts more than two hundred years. During that time, a lot sources about preparations course hostilities were introduced into scientific use. There are Russian chronicles, publicistic treatises novels, documental compilations etc. majority these been published. Therefore, great value lies in identification...
Abstract Objective: to study the differences in calcium-phosphorus and vitamin D metabolism healthy individuals with deficient sufficient baseline state of D. Materials methods: The included 16 young conditionally individuals, divided into two equal groups: levels 25(OH)D below above 30 ng/ml determined by immunochemiluminescent method (Group A Group B respectively; DEQAS certified). All participants were evaluated for biochemical parameters blood urine, characterizing metabolism, PTH...