- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Antimicrobial Resistance in Staphylococcus
- Botanical Research and Applications
- Phase Equilibria and Thermodynamics
- Antifungal resistance and susceptibility
- Bacterial biofilms and quorum sensing
- Plant biochemistry and biosynthesis
- Plant chemical constituents analysis
- Mycobacterium research and diagnosis
- Fungal Infections and Studies
- Bone Tissue Engineering Materials
- Microbial Metabolites in Food Biotechnology
- Chromatography in Natural Products
- Bacterial Identification and Susceptibility Testing
- Analytical Chemistry and Chromatography
- Cynara cardunculus studies
- Ethnobotanical and Medicinal Plants Studies
- Botany and Plant Ecology Studies
- Garlic and Onion Studies
- Curcumin's Biomedical Applications
- Enterobacteriaceae and Cronobacter Research
- Enzyme Catalysis and Immobilization
Medical University of Lublin
2014-2024
Warsaw University of Technology
2018
Antimicrobial resistance (AMR) is a global public health problem, and the rapid rise in AMR attributed to inappropriate and/or overuse of antibiotics. Therefore, alternative antimicrobial agents, including those natural origin, are being sought for development new drugs. The purpose our study was analyze chemical composition, antioxidant activities four oregano essential oils (OEOs) from Poland, Europe, Turkey USA. activity (AMA) evaluated using 23 strains, Gram-positive bacteria,...
The antimicrobial properties of essential oil from Lavandula sp. raise hopes related to its use in phytotherapy. This study aimed evaluate the activity oils cultivars L. angustifolia (‘Hidcote Blue Strain’, ‘Hidcote Blue’) and × intermedia (‘Phenomenal’, ‘Grosso’) grown central-eastern Poland, that is, at border northern lavender cultivation range. chemical composition was determined by GC/MS. Essential concentrations (20, 10, 5, 2.5, 1.25, 0.6, 0.3, 0.16, 0.08, 0.04 mg/mL) were tested...
Curcuma longa from Zingiberaceae belongs to the major spices consumed around world, known its cholagogue, anti-inflammatory, and antimicrobial properties. Lack of data on activity single components turmeric extract encouraged authors apply TLC (thin-layer chromatography) based bioautography studies reveal constituents construct a universal platform for bioactivity assessment crude extracts, with help freeware ImageJ software. This optimized chromatographic bioassay performed diethyl ether...
The aim of the study was to evaluate possible correlation between bioactivity and phytochemical profile four betalain-rich extracts from Portulaca grandiflora Hook. HPLC-DAD-ESI-MS analysis indicated presence 19 betaxanthins two betacyanins. highest concentrations (982 mg/100 g DE) betacyanins (650 were noticed in orange purple flowers extracts, respectively. HPLC-DAD-ESI-HRMS/MS analyses revealed a total 71 compounds. Fifteen new fifty other metabolites identified for first time....
Amaranth is used as a spinach replacement; therefore, it sometimes called Chinese Spinach. So far, the activity of plant has not been associated with presence specific compounds. Three cultivars Amaranthus tricolor L. were investigated for their antioxidant and antimicrobial activities. The correlation between bioactivity metabolite profiles was in order to indicate active compounds A. tricolor. phytochemical profile total nine extracts studied by HPLC-DAD-ESI/HRMS, revealing 52 highest...
The root of Carlina acaulis L. has been widely used in traditional medicine for its antimicrobial properties. In this study, the fractionation methanol extract from was conducted. Four fractions (A, B, C, and D) were obtained tested against a range bacteria fungi. results showed promising antibacterial activity, especially Bacillus cereus, where minimal inhibitory concentration (MIC) determined to be equal 0.08 mg/mL 0.16 heptane (fraction B) ethyl acetate C), respectively. case...
In the present article, we describe inhibitory potency of nine thiosemicarbazide derivatives against bacterial type IIA topoisomerases, their antibacterial profile and molecular modelling evaluation. We found that one tested compounds, compound 7, significantly inhibits activity Staphylococcus aureus DNA gyrase with an IC(50) below 15 μM. Besides, this displays on reference Staphylococuss spp. Enterococcus faecalis strains as well clinical S. isolates at non-cytotoxic concentrations in...
Extracts from the June collection of aerial parts Helianthus salicifolius A. Dietr and tuberosus L. were obtained using carbon dioxide supercritical fluid extraction with water as co-solvent. The antimicrobial effect in vitro these extracts was then determined against reference species bacteria, well fungi (represented by Candida spp.). Both found to possess activity, MIC = 0.62–5 mg mL−1 for bacteria 5–10 yeasts, both demonstrated suitable bactericidal fungicidal effect. highest activity...
The extracts from the aerial parts of Helianthus salicifolius A. Dietr and tuberosus L. collected in June were obtained using carbon dioxide supercritical fluid extraction with water as co-solvent. antimicrobial activity vitro these determined against reference species Gram-positive Gram-negative bacteria well fungi, representing by yeast Candida spp. following parameters estimated: minimum inhibitory concentration (MIC) bactericidal (MBC) or fungicidal (MFC). Both found to possess MIC =...
The laser micro-machining was carried out on a station equipped with TruMicro 5325c emitting ultraviolet radiation (343 nm wavelength) in picosecond pulses. On the surface of Ti6Al7Nb alloy, dimple texturing constant diameter ~200 μm, different depths (from ~5 to ~78 μm) and density 10% 50%) were produced. value free energy determined Owens-Wendt method using two measuring liquids: distilled water diodomethane. Staphylococcus epidermidis strain used test adhesion bacteria. It found that is...
Numerous species of Allium genus have been used in the traditional medicine based on their vast biological effects, e.g., antimicrobial, digestion stimulant, anti-sclerotic, soothing, antiradical or wound healing properties. In this work, unpolar and polar extracts from two lesser-investigated growing Kazakhstan, Alliumgalanthum Kar. & Kir. (AG) A. turkestanicum Regel. (AT), were studied for composition effects. HPLC-ESI-QTOF-MS/MS analyses water alcoholic simple organic acids, flavonoids...
is one of the most widely cultivated non-food crops used in production essential oil; it perfumery, aromatherapy, pharmaceutical preparations, and food ingredients. In this study, supercritical fluid extraction (SFE) molecular distillation (MD) were combined, primarily to enrich scCO
Beta vulgaris L. is an edible plant with health-beneficial activities. The profile of betaxanthins more complex than previously described in beetroot cultivars. Twenty-four were detected extracts the peel and flesh five cultivars by HPLC-DAD-ESI-MS, which two new (arginine-Bx ornithine-Bx) for first time B. content studied decreased Tytus > Ceryl Chrobry Forono Boldor sequence. highest compounds (1231 mg/100 g DE) was observed cultivar (peel). vulgaris, often considered a waste, appeared to...
Geranium robertianum L. is a widely distributed plant used as traditional herbal medicine, but the knowledge of its biological properties still needs to be improved. Thus, purpose this presented research was assess phytochemical profile extracts from aerial parts G. robertianum, commercially available in Poland and study their anticancer potential antimicrobial properties, including antiviral, antibacterial, antifungal effects. Additionally, bioactivity fractions obtained hexane ethyl...
Abstract The series of novel Mannich bases were synthesized and evaluated for their in vitro antibacterial activity against Gram‐positive Gram‐negative bacterial strains. results showed that all compounds less active than the drugs used as reference, but some them had moderate potency Staphylococcus epidermidis ATCC 12228 Bacillus subtilis 6633. presence a phenyl ring position 4 piperazine seems to be necessary this class compounds.
This study investigates the underutilized potential of agri-crops from
Patients with chronic lymphocytic leukemia (CLL) have defects in both humoral and cellular immunity as a result of their underlying malignancy, well chemotherapy-related immune suppression. Upper respiratory tract (URT) colonization can be regarded major contributor to infection, so the relationship between carriage rates, disease incidence, or antibiotic resistance should monitored. This prospective study included 50 newly diagnosed, previously untreated patients CLL 38 healthy volunteers....